Immunogenicity 13148
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CLIC6
Transcript ID
uc010gmt.1
HLA INFO
C*02:02
TCR INFO
No TCR info found!
Full length protein sequence (704 aa)
MAEAA
1
EPEGV
6
APGPQ
11
GPPEV
16
PAPLA
21
ERPGE
26
PGAAG
31
GEAEG
36
PEGSE
41
GAEEA
46
PRGAA
51
AVKEA
56
GGGGP
61
DRGPE
66
AEARG
71
TRGAH
76
GETEA
81
EEGAP
86
EGAEV
91
PQGGE
96
ETSGA
101
QQVEG
106
ASPGR
111
GAQGE
116
PRGEA
121
QREPE
126
DSAAP
131
ERQEE
136
AEQRP
141
EVPEG
146
SASGE
151
AGDSV
156
DAEGP
161
LGDNI
166
EAEGP
171
AGDSV
176
EAEGR
181
VGDSV
186
DAEGP
191
AGDSV
196
DAEGP
201
LGDNI
206
QAEGP
211
AGDSV
216
DAEGR
221
VGDSV
226
DAEGP
231
AGDSV
236
DAEGR
241
VGDSV
246
EAGDP
251
AGDGV
256
EAGVP
261
AGDSV
266
EAEGP
271
AGDSM
276
DAEGP
281
AGRAR
286
RVSGE
291
PQQSG
296
DGSLS
301
PQAEA
306
IEVAA
311
GESAG
316
RSPGE
321
LAWDA
326
AEEAE
331
VPGVK
336
GSEEA
341
APGDA
346
RADAG
351
EDRVG
356
DGPQQ
361
EPGED
366
EERRE
371
RSPEG
376
PREEE
381
AAGGE
386
EESPD
391
SSPHG
396
EASRG
401
AAEPE
406
AQLSN
411
HLAEE
416
GPAEG
421
SGEAA
426
RVNGR
431
REDGE
436
ASEPR
441
ALGQE
446
HDITL
451
FVKVK
456
LTALG
461
CSRIA
466
IKKYL
471
RAGYD
476
GESIG
481
NCPFS
486
QRLFM
491
ILWLK
496
GVIFN
501
VTTVD
506
LKRKP
511
ADLQN
516
LAPGT
521
NPPFM
526
TFDGE
531
VKTDV
536
NKIEE
541
FLEEK
546
LAPPR
551
YPKLG
556
TQHPE
561
SNSAG
566
NDVFA
571
KFSAF
576
IKNTK
581
KDANE
586
IHEKN
591
LLKAL
596
RKLDN
601
YLNSP
606
LPDEI
611
DAYST
616
EDVTV
621
SGRKF
626
LDGDE
631
LTLAD
636
CNLLP
641
KLHII
646
KIVAK
651
KYRDF
656
EFPSE
661
MTGIW
666
RYLNN
671
AYARD
676
EFTNT
681
CPADQ
686
EIEHA
691
YSDVA
696
KRMK
701
Mutation Information
DNA mutation:
None
Peptide Range:
502 ~ 526
Mut AA position:
514 (13 in Wild Type peptide)
Alignment
Wild Type:
"VIFNVTTVDLKRKPADLQNLAPGTN
||||||||||||.||||||||||||
Mutant:
VIFNVTTVDLKREPADLQNLAPGTN"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CLIC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay