Immunogenicity 13173
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CHEK2
Transcript ID
uc010gvh.1
HLA INFO
C*07:01
TCR INFO
No TCR info found!
Full length protein sequence (452 aa)
MSRES
1
DVEAQ
6
QSHGS
11
SACSQ
16
PHGSV
21
TQSQG
26
SSSQS
31
QGISS
36
SSTST
41
MPNSS
46
QSSHS
51
SSGTL
56
SSLET
61
VSTQE
66
LYSIP
71
EDQEP
76
EDQEP
81
EEPTP
86
APWAR
91
LWALQ
96
DGFAN
101
LVFVF
106
FDLTV
111
DDQSV
116
YPKAL
121
RDEYI
126
MSKTL
131
GSGAC
136
GEVKL
141
AFERK
146
TCKKV
151
AIKII
156
SKRKF
161
AIGSA
166
READP
171
ALNVE
176
TEIEI
181
LKKLN
186
HPCII
191
KIKNF
196
FDAED
201
YYIVL
206
ELMEG
211
GELFD
216
KVVGN
221
KRLKE
226
ATCKL
231
YFYQM
236
LLAVQ
241
YLHEN
246
GIIHR
251
DLKPE
256
NVLLS
261
SQEED
266
CLIKI
271
TDFGH
276
SKILG
281
ETSLM
286
RTLCG
291
TPTYL
296
APEVL
301
VSVGT
306
AGYNR
311
AVDCW
316
SLGVI
321
LFICL
326
SGYPP
331
FSEHR
336
TQVSL
341
KDQIT
346
SGKYN
351
FIPEV
356
WAEVS
361
EKALD
366
LVKKL
371
LVVDP
376
KARFT
381
TEEAL
386
RHPWL
391
QDEDM
396
KRKFQ
401
DLLSE
406
ENEST
411
ALPQV
416
LAQPS
421
TSRKR
426
PREGE
431
AEGAE
436
TTKRP
441
AVCAA
446
VL
451
Mutation Information
DNA mutation:
None
Peptide Range:
270 ~ 294
Mut AA position:
282 (13 in Wild Type peptide)
Alignment
Wild Type:
"DCLIKITDFGHSKILGETSLMRTLC
||||||||||||.||||||||||||
Mutant:
DCLIKITDFGHSEILGETSLMRTLC"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CHEK2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay