Immunogenicity 13180

summary
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CHEK2
Transcript ID
uc003adv.1
HLA INFO
B*08:01
TCR INFO

No TCR info found!

T cell Tumor cell B*08:01
sequence
Full length protein sequence (514 aa)
MSRES
1
DVEAQ
6
QSHGS
11
SACSQ
16
PHGSV
21
TQSQG
26
SSSQS
31
QGISS
36
SSTST
41
MPNSS
46
QSSHS
51
SSGTL
56
SSLET
61
VSTQE
66
LYSIP
71
EDQEP
76
EDQEP
81
EEPTP
86
APWAR
91
LWALQ
96
DGFAN
101
LECVN
106
DNYWF
111
GRDKS
116
CEYCF
121
DEPLL
126
KRTDK
131
YRTYS
136
KKHFR
141
IFREV
146
GPKNS
151
YIAYI
156
EDHSG
161
NGTFV
166
NTELV
171
GKGKR
176
RPLNN
181
NSEIA
186
LSLSR
191
NKVFV
196
FFDLT
201
VDDQS
206
VYPKA
211
LRDEY
216
IMSKT
221
LGSGA
226
CGEVK
231
LAFER
236
KTCKK
241
VAIKI
246
ISKRK
251
FAIGS
256
AREAD
261
PALNV
266
ETEIE
271
ILKKL
276
NHPCI
281
IKIKN
286
FFDAE
291
DYYIV
296
LELME
301
GGELF
306
DKVVG
311
NKRLK
316
EATCK
321
LYFYQ
326
MLLAV
331
QITDF
336
GHSKI
341
LGETS
346
LMRTL
351
CGTPT
356
YLAPE
361
VLVSV
366
GTAGY
371
NRAVD
376
CWSLG
381
VILFI
386
CLSGY
391
PPFSE
396
HRTQV
401
SLKDQ
406
ITSGK
411
YNFIP
416
EVWAE
421
VSEKA
426
LDLVK
431
KLLVV
436
DPKAR
441
FTTEE
446
ALRHP
451
WLQDE
456
DMKRK
461
FQDLL
466
SEENE
471
STALP
476
QVLAQ
481
PSTSR
486
KRPRE
491
GEAEG
496
AETTK
501
RPAVC
506
AAVL
511
Mutation Information
DNA mutation:
None
Peptide Range:
332 ~ 356
Mut AA position:
344 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLAVQITDFGHSKILGETSLMRTLC
||||||||||||.||||||||||||
Mutant:
LLAVQITDFGHSEILGETSLMRTLC"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay