Immunogenicity 1322
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
KDM5C
Transcript ID
ENST00000375379
HLA INFO
DRB*07:01
TCR INFO
No TCR info found!
Full length protein sequence (1557 aa)
MEPGS
1
DDFLP
6
PPECP
11
VFEPS
16
WAEFR
21
DPLGY
26
IAKIR
31
PIAEK
36
SGICK
41
IRPPA
46
DWQPP
51
FAVEV
56
DNFRF
61
TPRIQ
66
RLNEL
71
EAQTR
76
VKLNY
81
LDQIA
86
KFWEI
91
QGSSL
96
KIPNV
101
ERRIL
106
DLYSL
111
SKIVV
116
EEGGY
121
EAICK
126
DRRWA
131
RVAQR
136
LNYPP
141
GKNIG
146
SLLRS
151
HYERI
156
VYPYE
161
MYQSG
166
ANLVQ
171
CNTRP
176
FDNEE
181
KDKEY
186
KPHSI
191
PLRQS
196
VQPSK
201
FNSYG
206
RRAKR
211
LQPDP
216
EPTEE
221
DIEKN
226
PELKK
231
LQIYG
236
AGPKM
241
MGLGL
246
MAKDK
251
TLRKK
256
DKEGP
261
ECPPT
266
VVVKE
271
ELGGD
276
VKVES
281
TSPKT
286
FLESK
291
EELSH
296
SPEPC
301
TKMTM
306
RLRRN
311
HSNAQ
316
FIESY
321
VCRMC
326
SRGDE
331
DDKLL
336
LCDGC
341
DDNYH
346
IFCLL
351
PPLPE
356
IPKGV
361
WRCPK
366
CVMAE
371
CKRPP
376
EAFGF
381
EQATR
386
EYTLQ
391
SFGEM
396
ADSFK
401
ADYFN
406
MPVHM
411
VPTEL
416
VEKEF
421
WRLVN
426
SIEED
431
VTVEY
436
GADIH
441
SKEFG
446
SGFPV
451
SDSKR
456
HLTPE
461
EEEYA
466
TSGWN
471
LNVMP
476
VLEQS
481
VLCHI
486
NADIS
491
GMKVP
496
WLYVG
501
MVFSA
506
FCWHI
511
EDHWS
516
YSINY
521
LHWGE
526
PKTWY
531
GVPSL
536
AAEHL
541
EEVMK
546
KLTPE
551
LFDSQ
556
PDLLH
561
QLVTL
566
MNPNT
571
LMSHG
576
VPVVR
581
TNQCA
586
GEFVI
591
TFPRA
596
YHSGF
601
NQGYN
606
FAEAV
611
NFCTA
616
DWLPA
621
GRQCI
626
EHYRR
631
LRRYC
636
VFSHE
641
ELICK
646
MAACP
651
EKLDL
656
NLAAA
661
VHKEM
666
FIMVQ
671
EERRL
676
RKALL
681
EKGIT
686
EAERE
691
AFELL
696
PDDER
701
QCIKC
706
KTTCF
711
LSALA
716
CYDCP
721
DGLVC
726
LSHIN
731
DLCKC
736
SSSRQ
741
YLRYR
746
YTLDE
751
LPAML
756
HKLKV
761
RAESF
766
DTWAN
771
KVRVA
776
LEVED
781
GRKRS
786
LEELR
791
ALESE
796
ARERR
801
FPNSE
806
LLQQL
811
KNCLS
816
EAEAC
821
VSRAL
826
GLVSG
831
QEAGP
836
HRVAG
841
LQMTL
846
TELRA
851
FLDQM
856
NNLPC
861
AMHQI
866
GDVKG
871
VLEQV
876
EAYQA
881
EAREA
886
LASLP
891
SSPGL
896
LQSLL
901
ERGRQ
906
LGVEV
911
PEAQQ
916
LQRQV
921
EQARW
926
LDEVK
931
RTLAP
936
SARRG
941
TLAVM
946
RGLLV
951
AGASV
956
APSPA
961
VDKAQ
966
AELQE
971
LLTIA
976
ERWEE
981
KAHLC
986
LEARQ
991
KHPPA
996
TLEAI
1001
IREAE
1006
NIPVH
1011
LPNIQ
1016
ALKEA
1021
LAKAR
1026
AWIAD
1031
VDEIQ
1036
NGDHY
1041
PCLDD
1046
LEGLV
1051
AVGRD
1056
LPVGL
1061
EELRQ
1066
LELQV
1071
LTAHS
1076
WREKA
1081
SKTFL
1086
KKNSC
1091
YTLLE
1096
VLCPC
1101
ADAGS
1106
DSTKR
1111
SRWME
1116
KELGL
1121
YKSDT
1126
ELLGL
1131
SAQDL
1136
RDPGS
1141
VIVAF
1146
KEGEQ
1151
KEKEG
1156
ILQLR
1161
RTNSA
1166
KPSPL
1171
ASSST
1176
ASSTT
1181
SICVC
1186
GQVLA
1191
GAGAL
1196
QCDLC
1201
QDWFH
1206
GRCVS
1211
VPRLL
1216
SSPRP
1221
NPTSS
1226
PLLAW
1231
WEWDT
1236
KFLCP
1241
LCMRS
1246
RRPRL
1251
ETILA
1256
LLVAL
1261
QRLPV
1266
RLPEG
1271
EALQC
1276
LTERA
1281
ISWQG
1286
RARQA
1291
LASED
1296
VTALL
1301
GRLAE
1306
LRQRL
1311
QAEPR
1316
PEEPP
1321
NYPAA
1326
PASDP
1331
LREGS
1336
GKDMP
1341
KVQGL
1346
LENGD
1351
SVTSP
1356
EKVAP
1361
EEGSD
1366
LELLS
1371
SLLPQ
1376
LTGPV
1381
LELPE
1386
ATRAP
1391
LEELM
1396
MEGDL
1401
LEVTL
1406
DENHS
1411
IWQLL
1416
QAGQP
1421
PDLER
1426
IRTLL
1431
ELEKA
1436
ERHGS
1441
RARGR
1446
ALERR
1451
RRRKV
1456
DRGGE
1461
GDDPA
1466
REELE
1471
PKRVR
1476
SSGPE
1481
AEEVQ
1486
EEEEL
1491
EEETG
1496
GEGPP
1501
APIPT
1506
TGSPS
1511
TQENQ
1516
NGLEP
1521
AEGTT
1526
SGPSA
1531
PFSTL
1536
TPRLH
1541
LPCPQ
1546
QPPQQ
1551
QL
1556
Mutation Information
DNA mutation:
None
Peptide Range:
1536 ~ 1557
Mut AA position:
1548 (13 in Wild Type peptide)
Alignment
Wild Type:
"PFSTLTPRLHLPCPQQPPQQQL
||||||||||||.|||||||||
Mutant:
PFSTLTPRLHLPYPQQPPQQQL"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) KDM5C
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay