Immunogenicity 13243

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DNAH1
Transcript ID
uc011bef.2
HLA INFO
A*02:01
TCR INFO

No TCR info found!

T cell Tumor cell A*02:01
sequence
Full length protein sequence (4265 aa)
MEQPN
1
SKGYS
6
LGRTP
11
QGPEC
16
SSAPA
21
VQVGT
26
HRGLE
31
YNPGK
36
ILPGS
41
DYGLG
46
NPPAL
51
DPKLP
56
HLPLP
61
PAPPT
66
LSDLG
71
QPRKS
76
PLTGT
81
DKKYP
86
LMKQR
91
GFYSD
96
ILSPG
101
TLDQL
106
GEVCR
111
GPRMS
116
QNLLR
121
QADLD
126
KFTPR
131
VGSFE
136
VPEDF
141
QERME
146
QQCIG
151
STTRL
156
LAQTD
161
FPLQA
166
YEPKM
171
QVPFQ
176
VLPGQ
181
HPRKI
186
EIERR
191
KQQYL
196
SLDIE
201
QLLFS
206
QGIDS
211
NKLMP
216
RHLDH
221
QHPQT
226
IEQGH
231
DPIFP
236
IYLPL
241
KVFDN
246
EDFDC
251
RTPRE
256
WINMG
261
LEPGS
266
LDRKP
271
VPGKA
276
LLPTD
281
DFLGH
286
EDPKS
291
QKLKY
296
KWCEV
301
GVLDY
306
DEEKK
311
LYLVH
316
KTDEK
321
GLVRD
326
EMGRP
331
ILNAG
336
VTTEG
341
RPPLQ
346
VCQYW
351
VPRIQ
356
LLFCA
361
EDPCM
366
FAQRV
371
VQANA
376
LRKNT
381
EALLL
386
YNLYV
391
DCMPS
396
DGQHV
401
ISEQS
406
LSKIK
411
QWALS
416
TPRMR
421
KGPSV
426
LEHLS
431
SLARE
436
VSLDY
441
ERSMN
446
KINFD
451
HVVSS
456
KPETF
461
SYVTL
466
PKKEE
471
EQVPE
476
RGLVS
481
VPKYH
486
FWEQK
491
EDFTF
496
VSLLT
501
RPEVI
506
TALSK
511
VRAEC
516
NKVTA
521
MSLFH
526
SSLSK
531
YSHLE
536
EFEQI
541
QSQTF
546
SQVQM
551
FLKDS
556
WISSL
561
KVAMR
566
SSLRD
571
MSKGW
576
YNLYE
581
TNWEV
586
YLMSK
591
LRKLM
596
ELVKY
601
MLQDT
606
LRFLV
611
QDSLA
616
SFSQF
621
ISDTC
626
CSVLN
631
CTDDM
636
VWGDD
641
LINSP
646
YRPRK
651
NPLFI
656
MDLVL
661
DSSGV
666
HYSTP
671
LEQFE
676
ASLLN
681
LFDKG
686
ILATH
691
AVPQL
696
EKLVM
701
EDIFI
706
SGDPL
711
LESVG
716
LHEPL
721
VEELR
726
ATIAS
731
AVSKA
736
MIPLQ
741
AYAKE
746
YRKYL
751
ELNNN
756
DIASF
761
LKTYQ
766
TQGLL
771
AQEVR
776
EVVLT
781
HLREK
786
EILDS
791
SLPSS
796
IIIGP
801
FYINT
806
DNVKQ
811
SLSKK
816
RKALA
821
TSVLD
826
ILAKN
831
LHKEV
836
DSICE
841
EFRSI
846
SRKIY
851
EKPNS
856
IEELA
861
ELREW
866
MKGIP
871
ERLVG
876
LEERI
881
VKVMD
886
DYQVM
891
DEFLY
896
NLSSD
901
DFNDK
906
WIASN
911
WPSKI
916
LGQIE
921
LVQQQ
926
HVEDE
931
EKFRK
936
IQIMD
941
QNNFQ
946
EKLEG
951
LQLVV
956
AGFSI
961
HVEIS
966
RAHEI
971
ANEVR
976
RVKKQ
981
LKDCQ
986
QLAML
991
YNNRE
996
RIFSL
1001
PITNY
1006
DKLSR
1011
MVKEF
1016
QPYLD
1021
LWTTA
1026
SDWLR
1031
WSESW
1036
MNDPL
1041
SAIDA
1046
EQLEK
1051
NVVEA
1056
FKTMH
1061
KCVKQ
1066
FKDMP
1071
ACQEV
1076
ALDIR
1081
ARIEE
1086
FKPYI
1091
PLIQG
1096
LRNPG
1101
MRIRH
1106
WETLS
1111
NQINI
1116
NVRPK
1121
ANLTF
1126
ARCLE
1131
MNLQD
1136
HIESI
1141
SKVAE
1146
VAGKE
1151
YAIEQ
1156
ALDKM
1161
EKEWS
1166
TILFN
1171
VLPYK
1176
ATDTY
1181
ILKSP
1186
DEASQ
1191
LLDDH
1196
IVMTQ
1201
NMSFS
1206
PYKKP
1211
FEQRI
1216
NSWEN
1221
KLKLT
1226
QEVLE
1231
EWLNC
1236
QRSWL
1241
YLEPI
1246
FSSED
1251
INQQL
1256
PVESK
1261
RYQTM
1266
ERIWK
1271
KIMKN
1276
AYENR
1281
EVINV
1286
CSDLR
1291
MLDSL
1296
RDCNK
1301
ILDLV
1306
QKGLS
1311
EYLET
1316
KRSAF
1321
PRFYF
1326
LSDDE
1331
LLEIL
1336
SQTKD
1341
PTAVQ
1346
PHLRK
1351
CFENI
1356
ARLLF
1361
QEDLE
1366
ITHMY
1371
SAEGE
1376
EVQLC
1381
FSIYP
1386
SSNVE
1391
DWLRE
1396
VERSM
1401
KASVH
1406
DIIEK
1411
AIRAY
1416
PTMPR
1421
TQWVL
1426
NWPGQ
1431
VTIAG
1436
CQTYW
1441
TMEVA
1446
EALEA
1451
GNLRS
1456
QLFPQ
1461
LCQQL
1466
SDLVA
1471
LVRGK
1476
LSRMQ
1481
RAVLS
1486
ALIVI
1491
EVHAK
1496
DVVSK
1501
LIQEN
1506
VVSVN
1511
DFQWI
1516
SQLRY
1521
YWTNN
1526
DLYIR
1531
AVNAE
1536
FIYGY
1541
EYLGN
1546
SGRLV
1551
ITPLT
1556
DRCYL
1561
TLTGA
1566
LHLKF
1571
GGAPA
1576
GPAGT
1581
GKTET
1586
TKDLG
1591
KALAI
1596
QTVVF
1601
NCSDQ
1606
LDFMA
1611
MGKFF
1616
KGLAS
1621
AGAWA
1626
CFDEF
1631
NRIDI
1636
EVLSV
1641
VAQQI
1646
TTIQK
1651
AQQQR
1656
VERFM
1661
FEGVE
1666
IPLVP
1671
SCAVF
1676
ITMNP
1681
GYAGR
1686
TELPD
1691
NLKAL
1696
FRPVA
1701
MMVPD
1706
YAMIT
1711
EISLY
1716
SFGFN
1721
EASVL
1726
AKKIT
1731
TTFKL
1736
SSEQL
1741
SSQDH
1746
YDFGM
1751
RAVKT
1756
VISAA
1761
GNLKR
1766
ENPSM
1771
NEELI
1776
CLRAI
1781
RDVNV
1786
PKFLQ
1791
EDLKL
1796
FSGIV
1801
SDLFP
1806
TIKEE
1811
DTDYG
1816
ILDEA
1821
IREAC
1826
RNSNL
1831
KDVEG
1836
FLTKC
1841
IQLYE
1846
TTVVR
1851
HGLML
1856
VGPTG
1861
SGKST
1866
CYRVL
1871
AAAMT
1876
SLKGQ
1881
PSISG
1886
GMYEA
1891
VNYYV
1896
LNPKS
1901
ITMGQ
1906
LYGEF
1911
DLLTH
1916
EWTDG
1921
IFSSF
1926
IRAGA
1931
ITSDT
1936
NKKWY
1941
MFDGP
1946
VDAIW
1951
IENMN
1956
TVLDD
1961
NKKLC
1966
LSSGE
1971
IIKLT
1976
EAMTM
1981
MFEVQ
1986
DLAVA
1991
SPATV
1996
SRCGM
2001
VYLEP
2006
SILGL
2011
MPFIE
2016
CWLRK
2021
LPPLL
2026
KPYEE
2031
HFKAL
2036
FVSFL
2041
EESIS
2046
FVRSS
2051
VKEVI
2056
ASTNC
2061
NLTMS
2066
LLKLL
2071
DCFFK
2076
PFLPR
2081
EGLKK
2086
IPSEK
2091
LSRIV
2096
ELIEP
2101
WFIFS
2106
LIWSV
2111
GATGD
2116
SSGRT
2121
SFSHW
2126
LRLKM
2131
ENEQL
2136
TLLFP
2141
EEGLV
2146
FDYRL
2151
EDAGI
2156
SGTND
2161
SEDEE
2166
EEYKQ
2171
VAWVK
2176
WMDSS
2181
APFTM
2186
VPDTN
2191
YCNII
2196
VPTMD
2201
TVQMS
2206
HLLDM
2211
LLTNK
2216
KPVLC
2221
IGPTG
2226
TGKTL
2231
TISDK
2236
LLKNL
2241
ALDYI
2246
SHFLT
2251
FSART
2256
SANQT
2261
QDFID
2266
SKLDK
2271
RRKGV
2276
FGPPL
2281
GRNFI
2286
FFIDD
2291
LNMPA
2296
LETYG
2301
AQPPI
2306
ELLRQ
2311
WMDHG
2316
GWYDR
2321
KIIGA
2326
FKNLV
2331
DINFV
2336
CAMGP
2341
PGGGR
2346
NTVTP
2351
RLMRH
2356
FNYLS
2361
FAEMD
2366
EVSKK
2371
RIFST
2376
ILGNW
2381
LDGLL
2386
GEKSY
2391
RERVP
2396
GAPHI
2401
AHFTE
2406
PLVEA
2411
TIMVY
2416
ATITS
2421
QLLPT
2426
PAKSH
2431
YTFNL
2436
RDLSK
2441
VFQGM
2446
LMADP
2451
AKVED
2456
QVQLL
2461
RLWYH
2466
ENCRV
2471
FRDRL
2476
VNEED
2481
RSWFD
2486
QLLKR
2491
CMEQW
2496
EVTFN
2501
KVCPF
2506
QPILY
2511
GDFMS
2516
PGSDV
2521
KSYEL
2526
ITSES
2531
KMMQV
2536
IEEYI
2541
EDYNQ
2546
INTAK
2551
LKLVL
2556
FMDAM
2561
SHICR
2566
ISRTL
2571
RQALG
2576
NALLL
2581
GVGGS
2586
GRSSL
2591
TRLAS
2596
HMAEY
2601
ECFQI
2606
ELSKN
2611
YGMSE
2616
WRDDV
2621
KKVLL
2626
KAGLQ
2631
NLPIT
2636
FLFSD
2641
TQIKN
2646
ESFLE
2651
DINNV
2656
LNSGD
2661
IPNLY
2666
TADEQ
2671
DQIVS
2676
TMRPY
2681
IQEQG
2686
LQPTK
2691
ANLMA
2696
AYTGR
2701
VRSNI
2706
HMVLC
2711
MSPIG
2716
EVFRA
2721
RLRQF
2726
PSLVN
2731
CCTID
2736
WFNEW
2741
PAEAL
2746
KSVAT
2751
VFLNE
2756
IPELE
2761
SSQEE
2766
IQGLI
2771
QVCVY
2776
IHQSV
2781
SKKCI
2786
EYLAE
2791
LTRHN
2796
YVTPK
2801
SYLEL
2806
LHIFS
2811
ILIGQ
2816
KKLEL
2821
KTAKN
2826
RMKSG
2831
LDKLL
2836
RTSED
2841
VAKMQ
2846
EDLES
2851
MHPLL
2856
EEAAK
2861
DTMLT
2866
MEQIK
2871
VDTAI
2876
AEETR
2881
NSVQT
2886
EEIKA
2891
NEKAK
2896
KAQAI
2901
ADDAQ
2906
KDLDE
2911
ALPAL
2916
DAALA
2921
SLRNL
2926
NKNDV
2931
TEVRA
2936
MQRPP
2941
PGVKL
2946
VIEAV
2951
CIMKG
2956
IKPKK
2961
VPGEK
2966
PGTKV
2971
DDYWE
2976
PGKGL
2981
LQDPG
2986
HFLES
2991
LFKFD
2996
KDNIG
3001
DVVIK
3006
AIQPY
3011
IDNEE
3016
FQPAT
3021
IAKVS
3026
KACTS
3031
ICQWV
3036
RAMHK
3041
YHFVA
3046
KAVEP
3051
KRQAL
3056
LEAQD
3061
DLGVT
3066
QRILD
3071
EAKQR
3076
LREVE
3081
DGIAT
3086
MQAKY
3091
RECIT
3096
KKEEL
3101
ELKCE
3106
QCEQR
3111
LGRAG
3116
KLING
3121
LSDEK
3126
VRWQE
3131
TVENL
3136
QYMLN
3141
NISGD
3146
VLVAA
3151
GFVAY
3156
LGPFT
3161
GQYRT
3166
VLYDS
3171
WVKQL
3176
RSHNV
3181
PHTSE
3186
PTLIG
3191
TLGNP
3196
VKIRS
3201
WQIAG
3206
LPNDT
3211
LSVEN
3216
GVINQ
3221
FSQRW
3226
THFID
3231
PQSQA
3236
NKWIK
3241
NMEKD
3246
NGLDV
3251
FKLSD
3256
RDFLR
3261
SMENA
3266
IRFGK
3271
PCLLE
3276
NVGEE
3281
LDPAL
3286
EPVLL
3291
KQTYK
3296
QQGNT
3301
VLKLG
3306
DTVIP
3311
YHEDF
3316
RMYIT
3321
TKLPN
3326
PHYTP
3331
EISTK
3336
LTLIN
3341
FTLSP
3346
SGLED
3351
QLLGQ
3356
VVAEE
3361
RPDLE
3366
EAKNQ
3371
LIISN
3376
AKMRQ
3381
ELKDI
3386
EDQIL
3391
YRLSS
3396
SEGNP
3401
VDDME
3406
LIKVL
3411
EASKM
3416
KAAEI
3421
QAKVR
3426
IAEQT
3431
EKDID
3436
LTRME
3441
YIPVA
3446
IRTQI
3451
LFFCV
3456
SDLAN
3461
VDPMY
3466
QYSLE
3471
WFLNI
3476
FLSGI
3481
ANSER
3486
ADNLK
3491
KRISN
3496
INRYL
3501
TYSLY
3506
SNVCR
3511
SLFEK
3516
HKLMF
3521
AFLLC
3526
VRIMM
3531
NEGKI
3536
NQSEW
3541
RYLLS
3546
GGSIS
3551
IMTEN
3556
PAPDW
3561
LSDRA
3566
WRDIL
3571
ALSNL
3576
PTFSS
3581
FSSDF
3586
VKHLS
3591
EFRVI
3596
FDSLE
3601
PHREP
3606
LPGIW
3611
DQYLD
3616
QFQKL
3621
LVLRC
3626
LRGDK
3631
VTNAM
3636
QDFVA
3641
TNLEP
3646
RFIEP
3651
QTANL
3656
SVVFK
3661
DSNST
3666
TPLIF
3671
VLSPG
3676
TDPAA
3681
DLYKF
3686
AEEMK
3691
FSKKL
3696
SAISL
3701
GQGQG
3706
PRAEA
3711
MMRSS
3716
IERGK
3721
WVFFQ
3726
NCHLA
3731
PSWMP
3736
ALERL
3741
IEHIN
3746
PDKVH
3751
RDFRL
3756
WLTSL
3761
PSNKF
3766
PVSIL
3771
QNGSK
3776
MTIEP
3781
PRGVR
3786
ANLLK
3791
SYSSL
3796
GEDFL
3801
NSCHK
3806
VMEFK
3811
SLLLS
3816
LCLFH
3821
GNALE
3826
RRKFG
3831
PLGFN
3836
IPYEF
3841
TDGDL
3846
RICIS
3851
QLKMF
3856
LDEYD
3861
DIPYK
3866
VLKYT
3871
AGEIN
3876
YGGRV
3881
TDDWD
3886
RRCIM
3891
NILED
3896
FYNPD
3901
VLSPE
3906
HSYSA
3911
SGIYH
3916
QIPPT
3921
YDLHG
3926
YLSYI
3931
KSLPL
3936
NDMPE
3941
IFGLH
3946
DNANI
3951
TFAQN
3956
ETFAL
3961
LGTII
3966
QLQPK
3971
SSSAG
3976
SQGRE
3981
EIVED
3986
VTQNI
3991
LLKVP
3996
EPINL
4001
QWVMA
4006
KYPVL
4011
YEESM
4016
NTVLV
4021
QEVIR
4026
YNRLL
4031
QVITQ
4036
TLQDL
4041
LKALK
4046
GLVVM
4051
SSQLE
4056
LMAAS
4061
LYNNT
4066
VPELW
4071
SAKAY
4076
PSLKP
4081
LSSWV
4086
MDLLQ
4091
RLDFL
4096
QAWIQ
4101
DGIPA
4106
VFWIS
4111
GFFFP
4116
QAFLT
4121
GTLQN
4126
FARKF
4131
VISID
4136
TISFD
4141
FKVMF
4146
EAPSE
4151
LTQRP
4156
QVGCY
4161
IHGLF
4166
LEGAR
4171
WDPEA
4176
FQLAE
4181
SQPKE
4186
LYTEM
4191
AVIWL
4196
LPTPN
4201
RKAQD
4206
QDFYL
4211
CPIYK
4216
TLTRA
4221
GTLST
4226
TGHST
4231
NYVIA
4236
VEIPT
4241
HQPQR
4246
HWIKR
4251
GVALI
4256
CALDY
4261
Mutation Information
DNA mutation:
None
Peptide Range:
1472 ~ 1496
Mut AA position:
1484 (13 in Wild Type peptide)
Alignment
Wild Type:
"DLVALVRGKLSRMQRAVLSALIVIE
||||||||||||.||||||||||||
Mutant:
DLVALVRGKLSRVQRAVLSALIVIE"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay