Immunogenicity 13258
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HEG1
Transcript ID
uc011bke.2
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (1481 aa)
MASPR
1
ASRWP
6
PPLLL
11
LLLPL
16
LLLPP
21
AAPGT
26
RDPPP
31
SPARR
36
ALSLA
41
PLAGA
46
GLELQ
51
LERRP
56
EREPP
61
PTPPR
66
ERRGP
71
ATPGP
76
SYRAP
81
EPGAA
86
TQRGP
91
SGRAP
96
RGGSA
101
DAAWK
106
HWPES
111
NTEAH
116
VENIT
121
FYQNQ
126
EDFST
131
VSSKE
136
GVMVQ
141
TSGKS
146
HAASD
151
APENL
156
TLLAE
161
TADAR
166
GRSGS
171
SSRTN
176
FTILP
181
VGYSL
186
EIATA
191
LTSQS
196
GNLAS
201
ESLHL
206
PSSSS
211
EFDER
216
IAAFQ
221
TKSGT
226
ASEMG
231
TERAM
236
GLSEE
241
WTVHS
246
QEATT
251
SAWSP
256
SFLPA
261
LEMGE
266
LTTPS
271
RKRNS
276
SGPDL
281
SWLHF
286
YRTAA
291
SSPLL
296
DLSSS
301
SESTE
306
KLNNS
311
TGLQS
316
SSVSQ
321
TKTMH
326
VATVF
331
TDGGP
336
RTLRS
341
LTVSL
346
GPVSK
351
TEGFP
356
KDSRI
361
ATTSS
366
SVLLS
371
PSAVE
376
SRRNS
381
RVTGN
386
PGDEE
391
FIEPS
396
TENEF
401
GLTSL
406
RWQND
411
SPTFG
416
EHQLA
421
SSSEV
426
QNGSP
431
MSQTE
436
TVSRS
441
VAPMR
446
GGEIT
451
AHWLL
456
TNSTT
461
SADVT
466
GSSAS
471
YPEGV
476
NASVL
481
TQFSD
486
STVQS
491
GGSHT
496
ALGDR
501
SYSES
506
SSTSS
511
SESLN
516
SSAPR
521
GERST
526
LEDSR
531
EPGQA
536
LGDSS
541
ANAED
546
RTSGV
551
PSLGT
556
HTLAT
561
VTGNG
566
ERTLR
571
SVTLT
576
NTSMS
581
TTSGE
586
AGSPA
591
AAMHQ
596
ETEGA
601
SLHVN
606
VTDDM
611
GLVSR
616
SLAAS
621
SALGV
626
AGISY
631
GQVRG
636
TAIEQ
641
RTSSD
646
HTDHT
651
YLSST
656
FTKGE
661
RALLS
666
ITDNS
671
SSSDI
676
VESST
681
SYIKI
686
SNSSH
691
SEYSS
696
FFHAQ
701
TERSN
706
ISSYD
711
GEYAQ
716
PSTES
721
PVLHT
726
SNLPS
731
YTPTI
736
NMPNT
741
SVVLD
746
TDAEF
751
VSDSS
756
SSSSS
761
SSSSS
766
SSGPP
771
LPLPS
776
VSQSH
781
HLFSS
786
ILPST
791
RASVH
796
LLKST
801
SDAST
806
PWSSS
811
PSPLP
816
VSLTT
821
STSAP
826
LSVSQ
831
TTLPQ
836
SSSTP
841
VLPRA
846
RETPV
851
TSFQT
856
STMTS
861
FMTML
866
HSSQT
871
ADLKS
876
QSTPH
881
QEKVI
886
TESKS
891
PSLVS
896
LPTES
901
TKAVT
906
TNSPL
911
PPSLT
916
ESSTE
921
QTLPA
926
TSTNL
931
AQMSP
936
TFTTT
941
ILKTS
946
QPLMT
951
TPGTL
956
SSTAS
961
LVTGP
966
IAVQT
971
TAGKQ
976
LSLTH
981
PEILV
986
PQIST
991
EGGIS
996
TERNR
1001
VIVDA
1006
TTGLI
1011
PLTSV
1016
PTSAK
1021
EMTTK
1026
LGVTA
1031
EYSPA
1036
SRSLG
1041
TSPSP
1046
QTTVV
1051
STAED
1056
LAPKS
1061
ATFAV
1066
QSSTQ
1071
SPTTV
1076
SSSAS
1081
VNSCA
1086
VNPCL
1091
HNGEC
1096
VADNT
1101
SRGYH
1106
CRCPP
1111
SWQGD
1116
DCSVD
1121
VNECL
1126
SNPCP
1131
STAMC
1136
NNTQG
1141
SFICK
1146
CPVGY
1151
QLEKG
1156
ICNLV
1161
RTFVT
1166
EFKLK
1171
RTFLN
1176
TTVEK
1181
HSDLQ
1186
EVENE
1191
ITKTL
1196
NMCFS
1201
ALPSY
1206
IRSTV
1211
HASRE
1216
SNAVV
1221
ISLQT
1226
TFSLA
1231
SNVTL
1236
FDLAD
1241
RMQKC
1246
VNSCK
1251
SSAEV
1256
CQLLG
1261
SQRRI
1266
FRAGS
1271
LCKRK
1276
SPECD
1281
KDTSI
1286
CTDLD
1291
GVALC
1296
QCKSG
1301
YFQFN
1306
KMDHS
1311
CRACE
1316
DGYRL
1321
ENETC
1326
MSCPF
1331
GLGGL
1336
NCGNP
1341
YQLIT
1346
VVIAA
1351
AGGGL
1356
LLILG
1361
IALIV
1366
TCCRK
1371
NKNDI
1376
SKLIF
1381
KSGDF
1386
QMSPY
1391
AEYPK
1396
NPRSQ
1401
EWGRE
1406
AIEMH
1411
ENGST
1416
KNLLQ
1421
MTDVY
1426
YSPTS
1431
VRNPE
1436
LERNG
1441
LYPAY
1446
TGLPG
1451
SRHSC
1456
IFPGQ
1461
YNPSF
1466
ISDES
1471
RRRDY
1476
F
1481
Mutation Information
DNA mutation:
None
Peptide Range:
388 ~ 412
Mut AA position:
400 (13 in Wild Type peptide)
Alignment
Wild Type:
"TGNPGDEEFIEPSTENEFGLTSLRW
||||||||||||.||||||||||||
Mutant:
TGNPGDEEFIEPFTENEFGLTSLRW"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) HEG1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay