Immunogenicity 13376
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SEC24B
Transcript ID
uc011cfq.2
HLA INFO
B*27:02
TCR INFO
No TCR info found!
Full length protein sequence (1267 aa)
MSAPA
1
GSSHP
6
AASAR
11
IPPKF
16
GGAAV
21
SGAAA
26
PAGPG
31
AGPAP
36
HQQNG
41
PAQNQ
46
MQVPS
51
GYGLH
56
HQNYI
61
APSGH
66
YSQGP
71
GKMTS
76
LPLDT
81
QCGDY
86
YSALY
91
TVPTQ
96
NVTPN
101
TVNQQ
106
PGAQQ
111
LYSRG
116
PPAPH
121
IVGST
126
LGSFQ
131
GAASS
136
ASHLH
141
TSASQ
146
PYSSF
151
VNHYN
156
SPAMY
161
SASSS
166
VASQG
171
FPSTC
176
GHYAM
181
STVSN
186
AAYPS
191
VSYPS
196
LPAGD
201
TYGQM
206
FTSQN
211
APTVR
216
PVKDN
221
SFSGQ
226
NTAIS
231
HPSPL
236
PPLPS
241
QQHHQ
246
QQSLS
251
GYSTL
256
TWSSP
261
GLPST
266
QDNLI
271
RNHTG
276
SLAVA
281
NNNPT
286
ITVAD
291
SLSCP
296
VMQNV
301
QPPKS
306
SPVVS
311
TVLSG
316
SSGSS
321
STRTP
326
PTANH
331
PVEPV
336
TSVTQ
341
PSELL
346
QQKGV
351
QYGEY
356
VNNQA
361
SSAPT
366
PLSST
371
SDDEE
376
EEEED
381
EEAGV
386
DSSST
391
TSSAS
396
PMPNS
401
YDALE
406
GGSYP
411
DMLSS
416
SASSP
421
APDPA
426
PEPDP
431
ASAPA
436
PASAP
441
APVVP
446
QPSKM
451
AKPFG
456
YGYPT
461
LQPGY
466
QNATA
471
PLISG
476
VQPSN
481
PVYSG
486
FQQYP
491
QYPGV
496
NQLSS
501
SIGGL
506
SLQSS
511
PQPES
516
LRPVN
521
LTQER
526
NILPM
531
TPVWA
536
PVPNL
541
NADLK
546
KLNCS
551
PDSFR
556
CTLTN
561
IPQTQ
566
ALLNK
571
AKLPL
576
GLLLH
581
PFRDL
586
TQLPV
591
ITSNT
596
IVRCR
601
SCRTY
606
INPFV
611
SFIDQ
616
RRWKC
621
NLCYR
626
VNDVP
631
EEFMY
636
NPLTR
641
SYGEP
646
HKRPE
651
VQNST
656
VEFIA
661
SSDYM
666
LRPPQ
671
PAVYL
676
FVLDV
681
SHNAV
686
EAGYL
691
TILCQ
696
SLLEN
701
LDKLP
706
GDSRT
711
RIGFM
716
TFDST
721
IHFYN
726
LQEGL
731
SQPQM
736
LIVSD
741
IDDVF
746
LPTPD
751
SLLVN
756
LYESK
761
ELIKD
766
LLNAL
771
PNMFT
776
NTRET
781
HSALG
786
PALQA
791
AFKLM
796
SPTGG
801
RVSVF
806
QTQLP
811
SLGAG
816
LLQSR
821
EDPNQ
826
RSSTK
831
VVQHL
836
GPATD
841
FYKKL
846
ALDCS
851
GQQTA
856
VDLFL
861
LSSQY
866
SDLAS
871
LACMS
876
KYSAG
881
CIYYY
886
PSFHY
891
THNPS
896
QAEKL
901
QKDLK
906
RYLTR
911
KIGFE
916
AVMRI
921
RCTKG
926
LSMHT
931
FHGNF
936
FVRST
941
DLLSL
946
ANINP
951
DAGFA
956
VQLSI
961
EESLT
966
DTSLV
971
CFQTA
976
LLYTS
981
SKGER
986
RIRVH
991
TLCLP
996
VVSSL
1001
ADVYA
1006
GVDVQ
1011
AAICL
1016
LANMA
1021
VDRSV
1026
SSSLS
1031
DARDA
1036
LVNAV
1041
VDSLS
1046
AYGST
1051
VSNLQ
1056
HSALM
1061
APSSL
1066
KLFPL
1071
YVLAL
1076
LKQKA
1081
FRTGT
1086
STRLD
1091
DRVYA
1096
MCQIK
1101
SQPLV
1106
HLMKM
1111
IHPNL
1116
YRIDR
1121
LTDEG
1126
AVHVN
1131
DRIVP
1136
QPPLQ
1141
KLSAE
1146
KLTRE
1151
GAFLM
1156
DCGSV
1161
FYIWV
1166
GKGCD
1171
NNFIE
1176
DVLGY
1181
TNFAS
1186
IPQKM
1191
THLPE
1196
LDTLS
1201
SERAR
1206
SFITW
1211
LRDSR
1216
PLSPI
1221
LHIVK
1226
DESPA
1231
KAEFF
1236
QHLIE
1241
DRTEA
1246
AFSYY
1251
EFLLH
1256
VQQQI
1261
CK
1266
Mutation Information
DNA mutation:
None
Peptide Range:
359 ~ 383
Mut AA position:
371 (13 in Wild Type peptide)
Alignment
Wild Type:
"EYVNNQASSAPTPLSSTSDDEEEEE
||||||||||||.||||||||||||
Mutant:
EYVNNQASSAPTLLSSTSDDEEEEE"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) SEC24B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay