Immunogenicity 13443
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CDH6
Transcript ID
uc003jhe.2
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (790 aa)
MRTYR
1
YFLLL
6
FWVGQ
11
PYPTL
16
STPLS
21
KRTSG
26
FPAKK
31
RALEL
36
SGNSK
41
NELNR
46
SKRSW
51
MWNQF
56
FLLEE
61
YTGSD
66
YQYVG
71
KLHSD
76
QDRGD
81
GSLKY
86
ILSGD
91
GAGDL
96
FIINE
101
NTGDI
106
QATKR
111
LDREE
116
KPVYI
121
LRAQA
126
INRRT
131
GRPVE
136
PESEF
141
IIKIH
146
DINDN
151
EPIFT
156
KEVYT
161
ATVPE
166
MSDVG
171
TFVVQ
176
VTATD
181
ADDPT
186
YGNSA
191
KVVYS
196
ILQGQ
201
PYFSV
206
ESETG
211
IIKTA
216
LLNMD
221
RENRE
226
QYQVV
231
IQAKD
236
MGGQM
241
GGLSG
246
TTTVN
251
ITLTD
256
VNDNP
261
PRFPQ
266
STYQF
271
KTPES
276
SPPGT
281
PIGRI
286
KASDA
291
DVGEN
296
AEIEY
301
SITDG
306
EGLDM
311
FDVIT
316
DQETQ
321
EGIIT
326
VKKLL
331
DFEKK
336
KVYTL
341
KVEAS
346
NPYVE
351
PRFLY
356
LGPFK
361
DSATV
366
RIVVE
371
DVDEP
376
PVFSK
381
LAYIL
386
QIRED
391
AQINT
396
TIGSV
401
TAQDP
406
DAARN
411
PVKYS
416
VDRHT
421
DMDRI
426
FNIDS
431
GNGSI
436
FTSKL
441
LDRET
446
LLWHN
451
ITVIA
456
TEINN
461
PKQSS
466
RVPLY
471
IKVLD
476
VNDNA
481
PEFAE
486
FYETF
491
VCEKA
496
KADQL
501
IQTLH
506
AVDKD
511
DPYSG
516
HQFSF
521
SLAPE
526
AASGS
531
NFTIQ
536
DNKDN
541
TAGIL
546
TRKNG
551
YNRHE
556
MSTYL
561
LPVVI
566
SDNDY
571
PVQSS
576
TGTVT
581
VRVCA
586
CDHHG
591
NMQSC
596
HAEAL
601
IHPTG
606
LSTGA
611
LVAIL
616
LCIVI
621
LLVTV
626
VLFAA
631
LRRQR
636
KKEPL
641
IISKE
646
DIRDN
651
IVSYN
656
DEGGG
661
EEDTQ
666
AFDIG
671
TLRNP
676
EAIED
681
NKLRR
686
DIVPE
691
ALFLP
696
RRTPT
701
ARDNT
706
DVRDF
711
INQRL
716
KENDT
721
DPTAP
726
PYDSL
731
ATYAY
736
EGTGS
741
VADSL
746
SSLES
751
VTTDA
756
DQDYD
761
YLSDW
766
GPRFK
771
KLADM
776
YGGVD
781
SDKDS
786
Mutation Information
DNA mutation:
None
Peptide Range:
282 ~ 306
Mut AA position:
294 (13 in Wild Type peptide)
Alignment
Wild Type:
"PPGTPIGRIKASDADVGENAEIEYS
||||||||||||.||||||||||||
Mutant:
PPGTPIGRIKASNADVGENAEIEYS"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CDH6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay