Immunogenicity 13462

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ISL1
Transcript ID
uc003jor.3
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (349 aa)
MGDMG
1
DPPKK
6
KRLIS
11
LCVGC
16
GNQIH
21
DQYIL
26
RVSPD
31
LEWHA
36
ACLKC
41
AECNQ
46
YLDES
51
CTCFV
56
RDGKT
61
YCKRD
66
YIRLY
71
GIKCA
76
KCSIG
81
FSKND
86
FVMRA
91
RSKVY
96
HIECF
101
RCVAC
106
SRQLI
111
PGDEF
116
ALRED
121
GLFCR
126
ADHDV
131
VERAS
136
LGAGD
141
PLSPL
146
HPARP
151
LQMAA
156
EPISA
161
RQPAL
166
RPHVH
171
KQPEK
176
TTRVR
181
TVLNE
186
KQLHT
191
LRTCY
196
AANPR
201
PDALM
206
KEQLV
211
EMTGL
216
SPRVI
221
RVWFQ
226
NKRCK
231
DKKRS
236
IMMKQ
241
LQQQQ
246
PNDKT
251
NIQGM
256
TGTPM
261
VAASP
266
ERHDG
271
GLQAN
276
PVEVQ
281
SYQPP
286
WKVLS
291
DFALQ
296
SDIDQ
301
PAFQQ
306
LVNFS
311
EGGPG
316
SNSTG
321
SEVAS
326
MSSQL
331
PDTPN
336
SMVAS
341
PIEA
346
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 17
Mut AA position:
5 (5 in Wild Type peptide)
Alignment
Wild Type:
"MGDMGDPPKKKRLISLC
||||.||||||||||||
Mutant:
MGDMRDPPKKKRLISLC"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay