Immunogenicity 1348

summary
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
CYP24A1
Transcript ID
ENST00000216862
HLA INFO
B*44:03
TCR INFO

No TCR info found!

T cell Tumor cell B*44:03
sequence
Full length protein sequence (514 aa)
MSSPI
1
SKSRS
6
LAAFL
11
QQLRS
16
PRQPP
21
RLVTS
26
TAYTS
31
PQPRE
36
VPVCP
41
LTAGG
46
ETQNA
51
AALPG
56
PTSWP
61
LLGSL
66
LQILW
71
KGGLK
76
KQHDT
81
LVEYH
86
KKYGK
91
IFRMK
96
LGSFE
101
SVHLG
106
SPCLL
111
EALYR
116
TESAY
121
PQRLE
126
IKPWK
131
AYRDY
136
RKEGY
141
GLLIL
146
EGEDW
151
QRVRS
156
AFQKK
161
LMKPG
166
EVMKL
171
DNKIN
176
EVLAD
181
FMGRI
186
DELCD
191
ERGHV
196
EDLYS
201
ELNKW
206
SFESI
211
CLVLY
216
EKRFG
221
LLQKN
226
AGDEA
231
VNFIM
236
AIKTM
241
MSTFG
246
RMMVT
251
PVELH
256
KSLNT
261
KVWQD
266
HTLAW
271
DTIFK
276
SVKAC
281
IDNRL
286
EKYSQ
291
QPSAD
296
FLCDI
301
YHQNR
306
LSKKE
311
LYAAV
316
TELQL
321
AAVET
326
TANSL
331
MWILY
336
NLSRN
341
PQVQQ
346
KLLKE
351
IQSVL
356
PENQV
361
PRAED
366
LRNMP
371
YLKAC
376
LKESM
381
RLTPS
386
VPFTT
391
RTLDK
396
ATVLG
401
EYALP
406
KGTVL
411
MLNTQ
416
VLGSS
421
EDNFE
426
DSSQF
431
RPERW
436
LQEKE
441
KINPF
446
AHLPF
451
GVGKR
456
MCIGR
461
RLAEL
466
QLHLA
471
LCWIV
476
RKYDI
481
QATDN
486
EPVEM
491
LHSGT
496
LVPSR
501
ELPIA
506
FCQR
511
Mutation Information
DNA mutation:
None
Peptide Range:
477 ~ 501
Mut AA position:
489 (13 in Wild Type peptide)
Alignment
Wild Type:
"CWIVRKYDIQATDNEPVEMLHSGTL
||||||||||||.||||||||||||
Mutant:
CWIVRKYDIQATNNEPVEMLHSGTL"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) CYP24A1

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay