Immunogenicity 13486
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RAPGEF6
Transcript ID
uc010jdk.3
HLA INFO
C*12:03
TCR INFO
No TCR info found!
Full length protein sequence (827 aa)
MNSPV
1
DPGAR
6
QALRK
11
KPPER
16
TPEDL
21
NTIYS
26
YLHGM
31
EILSN
36
LREHQ
41
LRLMS
46
ARARY
51
ERYSG
56
NQVLF
61
CSETI
66
ARCWY
71
ILLSG
76
SVLVK
81
GSMVL
86
PPCSF
91
GKQFG
96
GKRGC
101
DCLVL
106
EPSEM
111
IVVEN
116
AKDNE
121
DSILQ
126
REIPA
131
RQSRR
136
RFRKI
141
NYKGE
146
RQTIT
151
DDVEV
156
NSYLS
161
LPADL
166
TKMHL
171
TENPH
176
PQVTH
181
VSSSQ
186
SGCSI
191
ASDSG
196
SSSLS
201
DIYQA
206
TESEV
211
GDVDL
216
TRLPE
221
GPVDS
226
EDDEE
231
EDEEI
236
DRTDP
241
LQGRD
246
LVREC
251
LEKEP
256
ADKTD
261
DDIEQ
266
LLEFM
271
HQLPA
276
FANMT
281
MSVRR
286
ELCSV
291
MIFEV
296
VEQAG
301
AIILE
306
DGQEL
311
DSWYV
316
ILNGT
321
VEISH
326
PDGKV
331
ENLFM
336
GNSFG
341
ITPTL
346
DKQYM
351
HGIVR
356
TKVDD
361
CQFVC
366
IAQQD
371
YWRIL
376
NHVEK
381
NTHKV
386
EEEGE
391
IVMVH
396
EHREL
401
DRSGT
406
RKGHI
411
VIKAT
416
PERLI
421
MHLIE
426
EHSIV
431
DPTYI
436
EDFLL
441
TYRTF
446
LESPL
451
DVGIK
456
LLEWF
461
KIDSL
466
RDKVT
471
RIVLL
476
WVNNH
481
FNDFE
486
GDPAM
491
TRFLE
496
EFEKN
501
LEDTK
506
MNGHL
511
RLLNI
516
ACAAK
521
AKWRQ
526
VVLQK
531
ASRES
536
PLQFS
541
LNGGS
546
EKGFG
551
IFVEG
556
VEPGS
561
KAADS
566
GLKRG
571
DQIME
576
VNGQN
581
FENIT
586
FMKAV
591
EILRN
596
NTHLA
601
LTVKT
606
NIFVF
611
KELLF
616
RTEQE
621
KSGVP
626
HIPKI
631
AEKKS
636
NRHSI
641
QHVPG
646
DIEQT
651
SQEKG
656
SKKVK
661
ANTVS
666
GGRNK
671
IRKIL
676
DKTRF
681
SILPP
686
KLFSD
691
GGLSQ
696
SQDDS
701
IVGTR
706
HCRHS
711
LAIMP
716
IPGTL
721
SSSSP
726
DLLQP
731
TTSML
736
DFSNP
741
SDIPD
746
QVIRV
751
FKVDQ
756
QSCYI
761
IISKD
766
TTAKE
771
VVFHA
776
VHEFG
781
LTGAS
786
DTYSL
791
CEVSV
796
TPEGV
801
IKQRR
806
LPDQF
811
SKLAD
816
RIQLN
821
GR
826
Mutation Information
DNA mutation:
None
Peptide Range:
82 ~ 106
Mut AA position:
94 (13 in Wild Type peptide)
Alignment
Wild Type:
"VLVKGSMVLPPCSFGKQFGGKRGCD
||||||||||||.||||||||||||
Mutant:
VLVKGSMVLPPCGFGKQFGGKRGCD"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) RAPGEF6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay