Immunogenicity 13519
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PCDHGA1
Transcript ID
uc011dan.2
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (823 aa)
MKIQK
1
KLTGC
6
SRLML
11
LCLSL
16
ELLLE
21
AGAGN
26
IHYSV
31
PEETD
36
KGSFV
41
GNIAK
46
DLGLQ
51
PQELA
56
DGGVR
61
IVSRG
66
RMPLF
71
ALNPR
76
SGSLI
81
TARRI
86
DREEL
91
CAQSM
96
PCLVS
101
FNILV
106
EDKMK
111
LFPVE
116
VEIID
121
INDNT
126
PQFQL
131
EELEF
136
KMNEI
141
TTPGT
146
RVSLP
151
FGQDL
156
DVGMN
161
SLQSY
166
QLSSN
171
PHFSL
176
DVQQG
181
ADGPQ
186
HPEMV
191
LQSPL
196
DREEE
201
AVHHL
206
ILTAS
211
DGGEP
216
VRSGT
221
LRIYI
226
QVVDA
231
NDNPP
236
AFTQA
241
QYHIN
246
VPENV
251
PLGTQ
256
LLMVN
261
ATDPD
266
EGANG
271
EVTYS
276
FHNVD
281
HRVAQ
286
IFRLD
291
SYTGE
296
ISNKE
301
PLDFE
306
EYKMY
311
SMEVQ
316
AQDGA
321
GLMAK
326
VKVLI
331
KVLDV
336
NDNAP
341
EVTIT
346
SVTTA
351
VPENF
356
PPGTI
361
IALIS
366
VHDQD
371
SGDNG
376
YTTCF
381
IPGNL
386
PFKLE
391
KLVDN
396
YYRLV
401
TERTL
406
DRELI
411
SGYNI
416
TITAI
421
DQGTP
426
ALSTE
431
THISL
436
LVTDI
441
NDNSP
446
VFHQD
451
SYSAY
456
IPENN
461
PRGAS
466
IFSVR
471
AHDLD
476
SNENA
481
QITYS
486
LIEDT
491
IQGAP
496
LSAYL
501
SINSD
506
TGVLY
511
ALRSF
516
DYEQF
521
RDMQL
526
KVMAR
531
DSGDP
536
PLSSN
541
VSLSL
546
FLLDQ
551
NDNAP
556
EILYP
561
ALPTD
566
GSTGV
571
ELAPL
576
SAEPG
581
YLVTK
586
VVAVD
591
RDSGQ
596
NAWLS
601
YRLLK
606
ASEPG
611
LFSVG
616
LHTGE
621
VRTAR
626
ALLDR
631
DALKQ
636
SLVVA
641
VQDHG
646
QPPLS
651
ATVTL
656
TVAVA
661
DRISD
666
ILADL
671
GSLEP
676
SAKPN
681
DSDLT
686
LYLVV
691
AAAAV
696
SCVFL
701
AFVIV
706
LLAHR
711
LRRWH
716
KSRLL
721
QASGG
726
GLASM
731
PGSHF
736
VGVDG
741
VRAFL
746
QTYSH
751
EVSLT
756
ADSRK
761
SHLIF
766
PQPNY
771
ADTLI
776
SQESC
781
EKKGF
786
LSAPQ
791
SLLED
796
KKEPF
801
SQVNF
806
CDECI
811
SYLEK
816
NNS
821
Mutation Information
DNA mutation:
None
Peptide Range:
281 ~ 305
Mut AA position:
293 (13 in Wild Type peptide)
Alignment
Wild Type:
"FHNVDHRVAQIFRLDSYTGEISNKE
||||||||||||.||||||||||||
Mutant:
FHNVDHRVAQIFCLDSYTGEISNKE"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) PCDHGA1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay