Immunogenicity 13550

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
HIVEP1
Transcript ID
uc003nac.3
HLA INFO
C*12:03
TCR INFO

No TCR info found!

T cell Tumor cell C*12:03
sequence
Full length protein sequence (2718 aa)
MPRTK
1
QIHPR
6
NLRDK
11
IEEAQ
16
KELNG
21
AEVSK
26
KEILQ
31
AGVKG
36
TSESL
41
KGVKR
46
KKIVA
51
ENHLK
56
KIPKS
61
PLRNP
66
LQAKH
71
KQNTE
76
ESSFA
81
VLHSA
86
SESHK
91
KQNYI
96
PVKNG
101
KQFTK
106
QNGET
111
PGIIA
116
EASKS
121
EESVS
126
PKKPL
131
FLQQP
136
SELRR
141
WRSEG
146
ADPAK
151
FSDLD
156
EQCDS
161
SSLSS
166
KTRTD
171
NSECI
176
SSHCG
181
TTSPS
186
YTNTA
191
FDVLL
196
KAMEP
201
ELSTL
206
SQKGS
211
PCAIK
216
TEKLR
221
PNKTA
226
RSPPK
231
LKNSS
236
MDAPN
241
QTSQE
246
LVAES
251
QSSCT
256
SYTVH
261
MSAAQ
266
KNEQG
271
AMQSA
276
SHLYH
281
QHEHF
286
VPKSN
291
QHNQQ
296
LPGCS
301
GFTGS
306
LTNLQ
311
NQENA
316
KLEQV
321
YNIAV
326
TSSVG
331
LTSPS
336
SRSQV
341
TPQNQ
346
QMDSA
351
SPLSI
356
SPANS
361
TQSPP
366
MPIYN
371
STHVA
376
SVVNQ
381
SVEQM
386
CNLLL
391
KDQKP
396
KKQGK
401
YICEY
406
CNRAC
411
AKPSV
416
LLKHI
421
RSHTG
426
ERPYP
431
CVTCG
436
FSFKT
441
KSNLY
446
KHKKS
451
HAHTI
456
KLGLV
461
LQPDA
466
GGLFL
471
SHESP
476
KALSI
481
HSDVE
486
DSGES
491
EEEGA
496
TDERQ
501
HDLGA
506
MELQP
511
VHIIK
516
RMSNA
521
ETLLK
526
SSFTP
531
SSPEN
536
VIGDF
541
LLQDR
546
SAESQ
551
AVTEL
556
PKVVV
561
HHVTV
566
SPLRT
571
DSPKA
576
MDPKP
581
ELSSA
586
QKQKD
591
LQVTN
596
VQPLS
601
ANMSQ
606
GGVSR
611
LETNE
616
NSHQK
621
GDMNP
626
LEGKQ
631
DSHVG
636
TVHAQ
641
LQRQQ
646
ATDYS
651
QEQQG
656
KLLSP
661
RSLGS
666
TDSGY
671
FSRSE
676
SADQT
681
VSPPT
686
PFARR
691
LPSTE
696
QDSGR
701
SNGPS
706
AALVT
711
TSTPS
716
ALPTG
721
EKALL
726
LPGQM
731
RPPLA
736
TKTLE
741
ERISK
746
LISDN
751
EALVD
756
DKQLD
761
SVKPR
766
RTSLS
771
RRGSI
776
DSPKS
781
YIFKD
786
SFQFD
791
LKPVG
796
RRTSS
801
SSDIP
806
KSPFT
811
PTEKS
816
KQVFL
821
LSVPS
826
LDCLP
831
ITRSN
836
SMPTT
841
GYSAV
846
PANII
851
PPPHP
856
LRGSQ
861
SFDDK
866
IGTFY
871
DDVFV
876
SGPNA
881
PVPQS
886
GHPRT
891
LVRQA
896
AIEDS
901
SANES
906
HVLGT
911
GQSLD
916
ESHQG
921
CHAAG
926
EAMSV
931
RSKAL
936
AQGPH
941
IEKKK
946
SHQGR
951
GTMFE
956
CETCR
961
NRYRK
966
LENFE
971
NHKKF
976
YCSEL
981
HGPKT
986
KVAMR
991
EPEHS
996
PVPGG
1001
LQPQI
1006
LHYRV
1011
AGSSG
1016
IWEQT
1021
PQIRK
1026
RRKMK
1031
SVGDD
1036
EELQQ
1041
NESGT
1046
SPKSS
1051
EGLQF
1056
QNALG
1061
CNPSL
1066
PKHNV
1071
TIRSD
1076
QQHKN
1081
IQLQN
1086
SHIHL
1091
VARGP
1096
EQTMD
1101
PKLST
1106
IMEQQ
1111
ISSAA
1116
QDKIE
1121
LQRHG
1126
TGISV
1131
IQHTN
1136
SLSRP
1141
NSFDK
1146
PEPFE
1151
RASPV
1156
SFQEL
1161
NRTGK
1166
SGSLK
1171
VIGIS
1176
QEESH
1181
PSRDG
1186
SHPHQ
1191
LALSD
1196
ALRGE
1201
LQESS
1206
RKSPS
1211
ERHVL
1216
GQPSR
1221
LVRQH
1226
NIQVP
1231
EILVT
1236
EEPDR
1241
DLEAQ
1246
CHDQE
1251
KSEKF
1256
SWPQR
1261
SETLS
1266
KLPTE
1271
KLPPK
1276
KKRLR
1281
LAEIE
1286
HSSTE
1291
SSFDS
1296
TLSRS
1301
LSRES
1306
SLSHT
1311
SSFSA
1316
SLDIE
1321
DVSKT
1326
EASPK
1331
IDFLN
1336
KAEFL
1341
MIPAG
1346
LNTLN
1351
VPGCH
1356
REMRR
1361
TASEQ
1366
INCTQ
1371
TSMEV
1376
SDLRS
1381
KSFDC
1386
GSITP
1391
PQTTP
1396
LTELQ
1401
PPSSP
1406
SRVGV
1411
TGHVP
1416
LLERR
1421
RGPLV
1426
RQISL
1431
NIAPD
1436
SHLSP
1441
VHPTS
1446
FQNTA
1451
LPSVN
1456
AVPYQ
1461
GPQLT
1466
STSLA
1471
EFSAN
1476
TLHSQ
1481
TQVKD
1486
LQAET
1491
SNSSS
1496
TNVFP
1501
VQQLC
1506
DINLL
1511
NQIHA
1516
PPSHQ
1521
STQLS
1526
LQVST
1531
QGSKP
1536
DKNSV
1541
LSGSS
1546
KSEDC
1551
FAPKY
1556
QLHCQ
1561
VFTSG
1566
PSCSS
1571
NPVHS
1576
LPNQV
1581
ISDPV
1586
GTDHC
1591
VTSAT
1596
LPTKL
1601
IDSMS
1606
NSHPL
1611
LPPEL
1616
RPLGS
1621
QVQKV
1626
PSSFM
1631
LPIRL
1636
QSSVP
1641
AYCFA
1646
TLTSL
1651
PQILV
1656
TQDLP
1661
NQPIC
1666
QTNHS
1671
VVPIS
1676
EEQNS
1681
VPTLQ
1686
KGHQN
1691
ALPNP
1696
EKEFL
1701
CENVF
1706
SEMSQ
1711
NSSLS
1716
ESLPI
1721
TQKIS
1726
VGRLS
1731
PQQES
1736
SASSK
1741
RMLSP
1746
ANSLD
1751
IAMEK
1756
HQKRA
1761
KDENG
1766
AVCAT
1771
DVRPL
1776
EALSS
1781
RVNEA
1786
SKQKK
1791
PILVR
1796
QVCTT
1801
EPLDG
1806
VMLEK
1811
DVFSQ
1816
PEISN
1821
EAVNL
1826
TNVLP
1831
ADNSS
1836
TGCSK
1841
FVVIE
1846
PISEL
1851
QEFEN
1856
IKSST
1861
SLTLT
1866
VRSSP
1871
APSEN
1876
THISP
1881
LKCTD
1886
NNQER
1891
KSPGV
1896
KNQGD
1901
KVNIQ
1906
EQSQQ
1911
PVTSL
1916
SLFNI
1921
KDTQQ
1926
LAFPS
1931
LKTTT
1936
NFTWC
1941
YLLRQ
1946
KSLHL
1951
PQKDQ
1956
KTSAY
1961
TDWTV
1966
SASNP
1971
NPLGL
1976
PTKVA
1981
LALLN
1986
SKQNT
1991
GKSLY
1996
CQAIT
2001
THSKS
2006
DLLVY
2011
SSKWK
2016
SSLSK
2021
RALGN
2026
QKSTV
2031
VEFSN
2036
KDASE
2041
INSEQ
2046
DKENS
2051
LIKSE
2056
PRRIK
2061
IFDGG
2066
YKSNE
2071
EYVYV
2076
RGRGR
2081
GKYIC
2086
EECGI
2091
RCKKP
2096
SMLKK
2101
HIRTH
2106
TDVRP
2111
YHCTY
2116
CNFSF
2121
KTKGN
2126
LTKHM
2131
KSKAH
2136
SKKCV
2141
DLGVS
2146
VGLID
2151
EQDTE
2156
ESDEK
2161
QRFSY
2166
ERSGY
2171
DLEES
2176
DGPDE
2181
DDNEN
2186
EDDDE
2191
DSQAE
2196
SVLSA
2201
TPSVT
2206
ASPQH
2211
LPSRS
2216
SLQDP
2221
VSTDE
2226
DVRIT
2231
DCFSG
2236
VHTDP
2241
MDVLP
2246
RALLT
2251
RMTVL
2256
STAQS
2261
DYNRK
2266
TLSPG
2271
KARQR
2276
AARDE
2281
NDTIP
2286
SVDTS
2291
RSPCH
2296
QMSVD
2301
YPESE
2306
EILRS
2311
SMAGK
2316
AVAIT
2321
QSPSS
2326
VRLPP
2331
AAAEH
2336
SPQTA
2341
AGMPS
2346
VASPH
2351
PDPQE
2356
QKQQI
2361
TLQPT
2366
PGLPS
2371
PHTHL
2376
FSHLP
2381
LHSQQ
2386
QSRTP
2391
YNMVP
2396
VGGIH
2401
VVPAG
2406
LTYST
2411
FVPLQ
2416
AGPVQ
2421
LTIPA
2426
VSVVH
2431
RTLGT
2436
HRNTV
2441
TEVSG
2446
TTNPA
2451
GVAEL
2456
SSVVP
2461
CIPIG
2466
QIRVP
2471
GLQNL
2476
STPGL
2481
QSLPS
2486
LSMET
2491
VNIVG
2496
LANTN
2501
MAPQV
2506
HPPGL
2511
ALNAV
2516
GLQVL
2521
TANPS
2526
SQSSP
2531
APQAH
2536
IPGLQ
2541
ILNIA
2546
LPTLI
2551
PSVSQ
2556
VAVDA
2561
QGAPE
2566
MPASQ
2571
SKACE
2576
TQPKQ
2581
TSVAS
2586
ANQVS
2591
RTESP
2596
QGLPT
2601
VQREN
2606
AKKVL
2611
NPPAP
2616
AGDHA
2621
RLDGL
2626
SKMDT
2631
EKAAS
2636
ANHVK
2641
PKPEL
2646
TSIQG
2651
QPAST
2656
SQPLL
2661
KAHSE
2666
VFTKP
2671
SGQQT
2676
LSPDR
2681
QVPRP
2686
TALPR
2691
RQPTV
2696
HFSDV
2701
SSDDD
2706
EDRLV
2711
IAT
2716
Mutation Information
DNA mutation:
None
Peptide Range:
2596 ~ 2620
Mut AA position:
2608 (13 in Wild Type peptide)
Alignment
Wild Type:
"RTESPQGLPTVQRENAKKVLNPPAP
||||||||||||.||||||||||||
Mutant:
RTESPQGLPTVQQENAKKVLNPPAP"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay