Immunogenicity 1359

summary
Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TUBB8P12
Transcript ID
ENST00000573909
HLA INFO
DQA*01:02 / DQB*06:02
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:02 DQB*06:02
sequence
Full length protein sequence (410 aa)
MNMPS
1
TPLAP
6
TTGTA
11
TCSWS
16
ASTCT
21
TTRPA
26
VRPPS
31
FSHRP
36
PGNAA
41
LPSLM
46
PSRPT
51
QVAGQ
56
CGAGN
61
NWAKG
66
RYTEG
71
AELTE
76
SVMDV
81
VRKEA
86
ESCDC
91
LQGFQ
96
LTHSL
101
GGGTG
106
SGMGT
111
LLISK
116
IREEY
121
PDRII
126
NTFSI
131
LPSPK
136
VSDTV
141
VEPYN
146
ATLSV
151
HQLIE
156
NADET
161
FCIDN
166
EALYD
171
ICSRT
176
LKLPT
181
PTYGD
186
LNHLV
191
SATMS
196
GVTTC
201
LRFPG
206
QLNAD
211
LRKLA
216
VNMVP
221
FPRLH
226
FFMPG
231
FAPLT
236
SRGSQ
241
QYRAL
246
TVAEL
251
TQQMF
256
DAKNM
261
MAACD
266
PRHGC
271
YLTVA
276
AIFRG
281
RMPMR
286
EVDEQ
291
MFNIQ
296
DKNSS
301
YFADW
306
FPDNV
311
KTAVC
316
DIPPR
321
GLKMS
326
ATFIG
331
NNAAI
336
QELFT
341
CVSEQ
346
FTAMF
351
RRKAF
356
LHWYT
361
GEGMD
366
EMEFT
371
EAESN
376
MNDLV
381
SEYQQ
386
YQDAT
391
AEEEE
396
DEEYA
401
EEEVA
406
Mutation Information
DNA mutation:
None
Peptide Range:
57 ~ 81
Mut AA position:
69 (13 in Wild Type peptide)
Alignment
Wild Type:
"VAGQCGAGNNWAKGRYTEGAELTES
||||||||||||.||||||||||||
Mutant:
VAGQCGAGNNWAEGRYTEGAELTES"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000173213

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay