Immunogenicity 13628
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
AFDN
Transcript ID
uc021zim.1
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (1381 aa)
MDGVV
1
TVTPR
6
SMDAE
11
TYVEG
16
QRISE
21
TTMLQ
26
SGMKV
31
QFGAS
36
HVFKF
41
VDPSQ
46
DHALA
51
KRSVD
56
GGLMV
61
KGPRH
66
KPGIV
71
QETTF
76
DLGGD
81
IHSGT
86
ALPTS
91
KSTTR
96
LDSDR
101
VSSAS
106
STAER
111
GMVKP
116
MIRVE
121
QQPDY
126
RRQES
131
RTQDA
136
SGPEL
141
ILPAS
146
IEFRE
151
SSEDS
156
FLSAI
161
INYTN
166
SSTVH
171
FKLSP
176
TYVLY
181
MACRY
186
VLSNQ
191
YRPDI
196
SPTER
201
THKVI
206
AVVNK
211
MVSMM
216
EGVIQ
221
KQKNI
226
AGALA
231
FWMAN
236
ASELL
241
NFIKQ
246
DRDLS
251
RITLD
256
AQDVL
261
AHLVQ
266
MAFKY
271
LVHCL
276
QSELN
281
NYMPA
286
FLDDP
291
EENSL
296
QRPKI
301
DDVLH
306
TLTGA
311
MSLLR
316
RCRVN
321
AALTI
326
QLFSQ
331
LFHFI
336
NMWLF
341
NRLVT
346
DPDSG
351
LCSHY
356
WGAII
361
RQQLG
366
HIEAW
371
AEKQG
376
LELAA
381
DCHLS
386
RIVQA
391
TTLLT
396
MDKYA
401
PDDIP
406
NINST
411
CFKLN
416
SLQLQ
421
ALLQN
426
YHCAP
431
DEPFI
436
PTDLI
441
ENVVT
446
VAENT
451
ADELA
456
RSDGR
461
EVQLE
466
EDPDL
471
QLPFL
476
LPEDG
481
YSCDV
486
VRNIP
491
NGLQE
496
FLDPL
501
CQRGF
506
CRLIP
511
HTRSP
516
GTWTI
521
YFEGA
526
DYESH
531
LLREN
536
TELAQ
541
PLRKE
546
PEIIT
551
VTLKK
556
QNGMG
561
LSIVA
566
AKGAG
571
QDKLG
576
IYVKS
581
VVKGG
586
AADVD
591
GRLAA
596
GDQLL
601
SVDGR
606
SLVGL
611
SQERA
616
AELMT
621
RTSSV
626
VTLEV
631
AKQGA
636
IYHGL
641
ATLLN
646
QPSPM
651
MQRIS
656
DRRGS
661
GKPRP
666
KSEGF
671
ELYNN
676
STQNG
681
SPESP
686
QLPWA
691
EYSEP
696
KKLPG
701
DDRLM
706
KNRAD
711
HRSSP
716
NVANQ
721
PPSPG
726
GKSAY
731
ASGTT
736
AKITS
741
VSTGN
746
LCTEE
751
QTPPP
756
RPEAY
761
PIPTQ
766
TYTRE
771
YFTFP
776
ASKSQ
781
DRMAP
786
PQNQW
791
PNYEE
796
KPHMH
801
TDSNH
806
SSIAI
811
QRVTR
816
SQEEL
821
REDKA
826
YQLER
831
HRIEA
836
AMDRK
841
SDSDM
846
WINQS
851
SSLDS
856
STSSQ
861
EHLNH
866
SSKSV
871
TPAST
876
LTKSG
881
PGRWK
886
TPAAI
891
PATPV
896
AVSQP
901
IRTDL
906
PPPPP
911
PPPVH
916
YAGDF
921
DGMSM
926
DLPLP
931
PPPSA
936
NQIGL
941
PSAQV
946
AAAER
951
RKREE
956
HQRWY
961
EKEKA
966
RLEEE
971
RERKR
976
REQER
981
KLGQM
986
RTQSL
991
NPAPF
996
SPLTA
1001
QQMKP
1006
EKPST
1011
LQRPQ
1016
ETVIR
1021
ELQPQ
1026
QQPRT
1031
IERRD
1036
LQYIT
1041
VSKEE
1046
LSSGD
1051
SLSPD
1056
PWKRD
1061
AKEKL
1066
EKQQQ
1071
MHIVD
1076
MLSKE
1081
IQELQ
1086
SKPDR
1091
SAEES
1096
DRLRK
1101
LMLEW
1106
QFQKR
1111
LQESK
1116
QKDED
1121
DEEEE
1126
DDDVD
1131
TMLIM
1136
QRLEA
1141
ERRAR
1146
TAMPA
1151
ISVLD
1156
LLQDE
1161
ERRRQ
1166
QQLEE
1171
MRKRE
1176
AEDRA
1181
RQEEE
1186
RRRQE
1191
EERTK
1196
RDAEE
1201
KRRQE
1206
EGYYS
1211
RLEAE
1216
RRRQH
1221
DEAAR
1226
RLLEP
1231
EAPGL
1236
CRPPL
1241
PRDYE
1246
PPSPS
1251
PAPGA
1256
PPPPP
1261
QRNAS
1266
YLKTQ
1271
VLSPD
1276
SLFTA
1281
KFVAY
1286
NEEEE
1291
EEDCS
1296
LAGPN
1301
SYPGS
1306
TGAAV
1311
GAHDA
1316
CRDAK
1321
EKRSK
1326
SQDAD
1331
SPGSS
1336
GAPEN
1341
LTFKE
1346
RQRLF
1351
SQGQD
1356
VSNKV
1361
KASRK
1366
LTELE
1371
NELNT
1376
K
1381
Mutation Information
DNA mutation:
None
Peptide Range:
1 ~ 20
Mut AA position:
8 (8 in Wild Type peptide)
Alignment
Wild Type:
"MDGVVTVTPRSMDAETYVEG
|||||||.||||||||||||
Mutant:
MDGVVTVSPRSMDAETYVEG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) MLLT4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay