Immunogenicity 1368

Sample ID
4007
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
TUBB8P12
Transcript ID
ENST00000308911

HLA INFO
B*07:02
TCR INFO

No TCR info found!

T cell Tumor cell B*07:02
Full length protein sequence (444 aa)
MREIV
1
LTQTG
6
QCGNQ
11
IGAKF
16
WEVIS
21
DEHAI
26
DSAGT
31
YHGDS
36
HLQLE
41
RINVH
46
HHEAS
51
GGRYV
56
PRAVL
61
VDLEP
66
GTMDS
71
VHSGP
76
FGQVF
81
RPDNF
86
ISGQC
91
GAGNN
96
WAKGR
101
YTEGA
106
ELTES
111
VMDVV
116
RKEAE
121
SCDCL
126
QGFQL
131
THSLG
136
GGTGS
141
GMGTL
146
LISKI
151
REEYP
156
DRIIN
161
TFSIL
166
PSPKV
171
SDTVV
176
EPYNA
181
TLSVH
186
QLIEN
191
ADETF
196
CIDNE
201
ALYDI
206
CSRTL
211
KLPTP
216
TYGDL
221
NHLVS
226
ATMSG
231
VTTCL
236
RFPGQ
241
LNADL
246
RKLAV
251
NMVPF
256
PRLHF
261
FMPGF
266
APLTS
271
RGSQQ
276
YRALT
281
VAELT
286
QQMFD
291
AKNMM
296
AACDP
301
RHGCY
306
LTVAA
311
IFRGR
316
MPMRE
321
VDEQM
326
FNIQD
331
KNSSY
336
FADWF
341
PDNVK
346
TAVCD
351
IPPRG
356
LKMSA
361
TFIGN
366
NAAIQ
371
ELFTC
376
VSEQF
381
TAMFR
386
RKAFL
391
HWYTG
396
EGMDE
401
MEFTE
406
AESNM
411
NDLVS
416
EYQQY
421
QDATA
426
EEEED
431
EEYAE
436
EEVA
441
Mutation Information
DNA mutation:
None
Peptide Range:
91 ~ 117
Mut AA position:
103 (13 in Wild Type peptide)
Alignment
Wild Type:
"ISGQCGAGNNWAKGRYTEGAELTES--
||||||||||||.|.||||||||||
Mutant:
ISGQCGAGNNWAEGHYTEGAELTESVM"

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000173213

Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay