Immunogenicity 13717

summary
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
AKAP9
Transcript ID
uc003uli.3
HLA INFO
B*13:02
TCR INFO

No TCR info found!

T cell Tumor cell B*13:02
sequence
Full length protein sequence (3530 aa)
MKLEL
1
TNSKQ
6
KERQS
11
SEEIK
16
QLMGT
21
VEELQ
26
KRNHK
31
DSQFE
36
TDIVQ
41
RMEQE
46
TQRKL
51
EQLRA
56
ELDEM
61
YGQQI
66
VQMKQ
71
ELIRQ
76
HMAQM
81
EEMKT
86
RHKGE
91
MENAL
96
RSYSN
101
ITVNE
106
DQIKL
111
MNVAI
116
NELNI
121
KLQDT
126
NSQKE
131
KLKEE
136
LGLIL
141
EEKCA
146
LQRQL
151
EDLVE
156
ELSFS
161
REQIQ
166
RARQT
171
IAEQE
176
SKLNE
181
AHKSL
186
STVED
191
LKAEI
196
VSASE
201
SRKEL
206
ELKHE
211
AEVTN
216
YKIKL
221
EMLEK
226
EKNAV
231
LDRMA
236
ESQEA
241
ELERL
246
RTQLL
251
FSHEE
256
ELSKL
261
KEDLE
266
IEHRI
271
NIEKL
276
KDNLG
281
IHYKQ
286
QIDGL
291
QNEMS
296
QKIET
301
MQFEK
306
DNLIT
311
KQNQL
316
ILEIS
321
KLKDL
326
QQSLV
331
NSKSE
336
EMTLQ
341
INELQ
346
KEIEI
351
LRQEE
356
KEKGT
361
LEQEV
366
QELQL
371
KTELL
376
EKQMK
381
EKEND
386
LQEKF
391
AQLEA
396
ENSIL
401
KDEKK
406
TLEDM
411
LKIHT
416
PVSQE
421
ERLIF
426
LDSIK
431
SKSKD
436
SVWEK
441
EIEIL
446
IEENE
451
DLKQQ
456
CIQLN
461
EEIEK
466
QRNTF
471
SFAEK
476
NFEVN
481
YQELQ
486
EEYAC
491
LLKVK
496
DDLED
501
SKNKQ
506
ELEYK
511
SKLKA
516
LNEEL
521
HLQRI
526
NPTTV
531
KMKSS
536
VFDED
541
KTFVA
546
ETLEM
551
GEVVE
556
KDTTE
561
LMEKL
566
EVTKR
571
EKLEL
576
SQRLS
581
DLSEQ
586
LKQKH
591
GEISF
596
LNEEV
601
KSLKQ
606
EKEQV
611
SLRCR
616
ELEII
621
INHNR
626
AENVQ
631
SCDTQ
636
VSSLL
641
DGVVT
646
MTSRG
651
AEGSV
656
SKVNK
661
SFGEE
666
SKIMV
671
EDKVS
676
FENMT
681
VGEES
686
KQEQL
691
ILDHL
696
PSVTK
701
ESSLR
706
ATQPS
711
ENDKL
716
QKELN
721
VLKSE
726
QNDLR
731
LQMEA
736
QRICL
741
SLVYS
746
THVDQ
751
VREYM
756
ENEKD
761
KALCS
766
LKEEL
771
IFAQE
776
EKIKE
781
LQKIH
786
QLELQ
791
TMKTQ
796
ETGDE
801
GKPLH
806
LLIGK
811
LQKAV
816
SEECS
821
YFLQT
826
LCSVL
831
GEYYT
836
PALKC
841
EVNAE
846
DKENS
851
GDYIS
856
ENEDP
861
ELQDY
866
RYEVQ
871
DFQEN
876
MHTLL
881
NKVTE
886
EYNKL
891
LVLQT
896
RLSKI
901
WGQQT
906
DGMKL
911
EFGEE
916
NLPKE
921
ETEFL
926
SIHSQ
931
MTNLE
936
DIDVN
941
HKSKL
946
SSLQD
951
LEKTK
956
LEEQV
961
QELES
966
LISSL
971
QQQLK
976
ETEQN
981
YEAEI
986
HCLQK
991
RLQAV
996
SESTV
1001
PPSLP
1006
VDSVV
1011
ITESD
1016
AQRTM
1021
YPGSC
1026
VKKNI
1031
DGTIE
1036
FSGEF
1041
GVKEE
1046
TNIVK
1051
LLEKQ
1056
YQEQL
1061
EEEVA
1066
KVIVS
1071
MSIAF
1076
AQQTE
1081
LSRIS
1086
GGKEN
1091
TASSK
1096
QAHAV
1101
CQQEQ
1106
HYFNE
1111
MKLSQ
1116
DQIGF
1121
QTFET
1126
VDVKF
1131
KEEFK
1136
PLSKE
1141
LGEHG
1146
KEILL
1151
SNSDP
1156
HDIPE
1161
SKDCV
1166
LTISE
1171
EMFSK
1176
DKTFI
1181
VRQSI
1186
HDEIS
1191
VSSMD
1196
ASRQL
1201
MLNEE
1206
QLEDM
1211
RQELV
1216
RQYQE
1221
HQQAT
1226
ELLRQ
1231
AHMRQ
1236
MERQR
1241
EDQEQ
1246
LQEEI
1251
KRLNR
1256
QLAQR
1261
SSIDN
1266
ENLVS
1271
ERERV
1276
LLEEL
1281
EALKQ
1286
LSLAG
1291
REKLC
1296
CELRN
1301
SSTQT
1306
QNGNE
1311
NQGEV
1316
EEQTF
1321
KEKEL
1326
DRKPE
1331
DVPPE
1336
ILSNE
1341
RYALQ
1346
KANNR
1351
LLKIL
1356
LEVVK
1361
TTAAV
1366
EETIG
1371
RHVLG
1376
ILDRS
1381
SKSQS
1386
SASLI
1391
WRSEA
1396
EASVK
1401
SCVHE
1406
EHTRD
1411
ESIPS
1416
YSGSD
1421
MPRND
1426
INMWS
1431
KVTEE
1436
GTELS
1441
QRLVR
1446
SGFAG
1451
TEIDP
1456
ENEEL
1461
MLNIS
1466
SRLQA
1471
AVEKL
1476
LEAIS
1481
ETSSQ
1486
LEHAK
1491
VTQTE
1496
LMRES
1501
FRQKQ
1506
EATES
1511
LKCQE
1516
ELRER
1521
LHEES
1526
RAREQ
1531
LAVEL
1536
SKAEG
1541
VIDGY
1546
ADEKT
1551
LFERQ
1556
IQEKT
1561
DIIDR
1566
LEQEL
1571
LCASN
1576
RLQEL
1581
EAEQQ
1586
QIQEE
1591
RELLS
1596
RQKEA
1601
MKAEA
1606
GPVEQ
1611
QLLQE
1616
TEKLM
1621
KEKLE
1626
VQCQA
1631
EKVRD
1636
DLQKQ
1641
VKALE
1646
IDVEE
1651
QVSRF
1656
IELEQ
1661
EKNTE
1666
LMDLR
1671
QQNQA
1676
LEKQL
1681
EKMRK
1686
FLDEQ
1691
AIDRE
1696
HERDV
1701
FQQEI
1706
QKLEQ
1711
QLKVV
1716
PRFQP
1721
ISEHQ
1726
TREVE
1731
QLANH
1736
LKEKT
1741
DKCSE
1746
LLLSK
1751
EQLQR
1756
DIQER
1761
NEEIE
1766
KLEFR
1771
VRELE
1776
QALLV
1781
SADTF
1786
QKVED
1791
RKHFG
1796
AVEAK
1801
PELSL
1806
EVQLQ
1811
AERDA
1816
IDRKE
1821
KEITN
1826
LEEQL
1831
EQFRE
1836
ELENK
1841
NEEVQ
1846
QLHMQ
1851
LEIQK
1856
KESTT
1861
RLQEL
1866
EQENK
1871
LFKDD
1876
MEKLG
1881
LAIKE
1886
SDAMS
1891
TQDQH
1896
VLFGK
1901
FAQII
1906
QEKEV
1911
EIDQL
1916
NEQVT
1921
KLQQQ
1926
LKITT
1931
DNKVI
1936
EEKNE
1941
LIRDL
1946
ETQIE
1951
CLMSD
1956
QECVK
1961
RNREE
1966
EIEQL
1971
NEVIE
1976
KLQQE
1981
LANIG
1986
QKTSM
1991
NAHSL
1996
SEEAD
2001
SLKHQ
2006
LDVVI
2011
AEKLA
2016
LEQQV
2021
ETANE
2026
EMTFM
2031
KNVLK
2036
ETNFK
2041
MNQLT
2046
QELFS
2051
LKRER
2056
ESVEK
2061
IQSIP
2066
ENSVN
2071
VAIDH
2076
LSKDK
2081
PELEV
2086
VLTED
2091
ALKSL
2096
ENQTY
2101
FKSFE
2106
ENGKG
2111
SIINL
2116
ETRLL
2121
QLEST
2126
VSAKD
2131
LELTQ
2136
CYKQI
2141
KDMQE
2146
QGQFE
2151
TEMLQ
2156
KKIVN
2161
LQKIV
2166
EEKVA
2171
AALVS
2176
QIQLE
2181
AVQEY
2186
AKFCQ
2191
DNQTI
2196
SSEPE
2201
RTNIQ
2206
NLNQL
2211
REDEL
2216
GSDIS
2221
ALTLR
2226
ISELE
2231
SQVVE
2236
MHTSL
2241
ILEKE
2246
QVEIA
2251
EKNVL
2256
EKEKK
2261
LLELQ
2266
KLLEG
2271
NEKKQ
2276
REKEK
2281
KRSPQ
2286
DVEVL
2291
KTTTE
2296
LFHSN
2301
EESGF
2306
FNELE
2311
ALRAE
2316
SVATK
2321
AELAS
2326
YKEKA
2331
EKLQE
2336
ELLVK
2341
ETNMT
2346
SLQKD
2351
LSQVR
2356
DHLAE
2361
AKEKL
2366
SILEK
2371
EDETE
2376
VQESK
2381
KACMF
2386
EPLPI
2391
KLSKS
2396
IASQT
2401
DGTLK
2406
ISSSN
2411
QTPQI
2416
LVKNA
2421
GIQIN
2426
LQSEC
2431
SSEEV
2436
TEIIS
2441
QFTEK
2446
IEKMQ
2451
ELHAA
2456
EILDM
2461
ESRHI
2466
SETET
2471
LKREH
2476
YVAVQ
2481
LLKEE
2486
CGTLK
2491
AVIQC
2496
LRSKE
2501
GSSIP
2506
ELAHS
2511
DAYQT
2516
REICS
2521
SDSGS
2526
DWGQG
2531
IYLTH
2536
SQGFD
2541
IASEG
2546
RGEES
2551
ESATD
2556
SFPKK
2561
IKGLL
2566
RAVHN
2571
EGMQV
2576
LSLTE
2581
SPYSD
2586
GEDHS
2591
IQQVS
2596
EPWLE
2601
ERKAY
2606
INTIS
2611
SLKDL
2616
ITKMQ
2621
LQREA
2626
EVYDS
2631
SQSHE
2636
SFSDW
2641
RGELL
2646
LALQQ
2651
VFLEE
2656
RSVLL
2661
AAFRT
2666
ELTAL
2671
GTTDA
2676
VGLLN
2681
CLEQR
2686
IQEQG
2691
VEYQA
2696
AMECL
2701
QKADR
2706
RSLLS
2711
EIQAL
2716
HAQMN
2721
GRKIT
2726
LKREQ
2731
ESEKP
2736
SQELL
2741
EYNIQ
2746
QKQSQ
2751
MLEMQ
2756
VELSS
2761
MKDRA
2766
TELQE
2771
QLSSE
2776
KMVVA
2781
ELKSE
2786
LAQTK
2791
LELET
2796
TLKAQ
2801
HKHLK
2806
ELEAF
2811
RLEVK
2816
DKTDE
2821
VHLLN
2826
DTLAS
2831
EQKKS
2836
RELQW
2841
ALEKE
2846
KAKLG
2851
RSEER
2856
DKEEL
2861
EDLKF
2866
SLESQ
2871
KQRNL
2876
QLNLL
2881
LEQQK
2886
QLLNE
2891
SQQKI
2896
ESQRM
2901
LYDAQ
2906
LSEEQ
2911
GRNLE
2916
LQVLL
2921
ESEKV
2926
RIREM
2931
SSTLD
2936
REREL
2941
HAQLQ
2946
SSDGT
2951
GQSRP
2956
PLPSE
2961
DLLKE
2966
LQKQL
2971
EEKHS
2976
RIVEL
2981
LNETE
2986
KYKLD
2991
SLQTR
2996
QQMEK
3001
DRQVH
3006
RKTLQ
3011
TEQEA
3016
NTEGQ
3021
KKMHE
3026
LQSKV
3031
EDLQR
3036
QLEEK
3041
RQQVY
3046
KLDLE
3051
GQRLQ
3056
GIMQE
3061
FQKQE
3066
LEREE
3071
KRESR
3076
RILYQ
3081
NLNEP
3086
TTWSL
3091
TSDRT
3096
RNWVL
3101
QQKIE
3106
GETKE
3111
SNYAK
3116
LIEMN
3121
GGGTG
3126
CNHEL
3131
EMIRQ
3136
KLQCV
3141
ASKLQ
3146
VLPQK
3151
ASERL
3156
QFETA
3161
DDEDF
3166
IWVQE
3171
NIDEI
3176
ILQLQ
3181
KLTGQ
3186
QGEEP
3191
SLVSP
3196
STSCG
3201
SLTER
3206
LLRQN
3211
AELTG
3216
HISQL
3221
TEEKN
3226
DLRNM
3231
VMKLE
3236
EQIRW
3241
YRQTG
3246
AGRDN
3251
SSRFS
3256
LNGGA
3261
NIEAI
3266
IASEK
3271
EVWNR
3276
EKLTL
3281
QKSLK
3286
RAEAE
3291
VYKLK
3296
AELRN
3301
DSLLQ
3306
TLSPD
3311
SEHVT
3316
LKRIY
3321
GKYLR
3326
AESFR
3331
KALIY
3336
QKKYL
3341
LLLLG
3346
GFQEC
3351
EDATL
3356
ALLAR
3361
MGGQP
3366
AFTDL
3371
EVITN
3376
RPKGF
3381
TRFRS
3386
AVRVS
3391
IAISR
3396
MKFLV
3401
RRWHR
3406
VTGSV
3411
SININ
3416
RDGFG
3421
LNQGA
3426
EKTDS
3431
FYHSS
3436
GGLEL
3441
YGEPR
3446
HTTYR
3451
SRSDL
3456
DYIRS
3461
PLPFQ
3466
NRYPG
3471
TPADF
3476
NPGSL
3481
ACSQL
3486
QNYDP
3491
DRALT
3496
DYITR
3501
LEALQ
3506
RRLGT
3511
IQSGS
3516
TTQFH
3521
AGMRR
3526
Mutation Information
DNA mutation:
None
Peptide Range:
1558 ~ 1582
Mut AA position:
1570 (13 in Wild Type peptide)
Alignment
Wild Type:
"ERQIQEKTDIIDRLEQELLCASNRL
||||||||||||.||||||||||||
Mutant:
ERQIQEKTDIIDCLEQELLCASNRL"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay