Immunogenicity 1374
Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
UNC13B
Transcript ID
ENST00000378495
HLA INFO
A*29:02
TCR INFO
No TCR info found!
Full length protein sequence (1591 aa)
MSLLC
1
VRVKR
6
AKFQG
11
SPDKF
16
NTYVT
21
LKVQN
26
VKSTT
31
VAVRG
36
DQPSW
41
EQDFM
46
FEISR
51
LDLGL
56
SVEVW
61
NKGLI
66
WDTMV
71
GTVWI
76
ALKTI
81
RQSDE
86
EGPGE
91
WSTLE
96
AETLM
101
KDDEI
106
CGTRN
111
PTPHK
116
ILLDT
121
RFELP
126
FDIPE
131
EEARY
136
WTYKW
141
EQINA
146
LGADN
151
EYSSQ
156
EESQR
161
KPLPT
166
AAAQC
171
SFEDP
176
DSAVD
181
DRDSD
186
YRSET
191
SNSFP
196
PPYHT
201
ASQPN
206
ASVHQ
211
FPVPV
216
RSPQQ
221
LLLQG
226
SSRDS
231
CNDSM
236
QSYDL
241
DYPER
246
RAISP
251
TSSSR
256
YGSSC
261
NVSQG
266
SSQLS
271
ELDQY
276
HEQDD
281
DHRET
286
DSIHS
291
CHSSH
296
SLSRD
301
GQAGF
306
GEQEK
311
PLEVT
316
GQAEK
321
EAACE
326
PKEMK
331
EDATT
336
HPPPD
341
LVLQK
346
DHFLG
351
PQESF
356
PEENA
361
SSPFT
366
QARAH
371
WIRAV
376
TKVRL
381
QLQEI
386
PDDGD
391
PSLPQ
396
WLPEG
401
PAGGL
406
YGIDS
411
MPDLR
416
RKKPL
421
PLVSD
426
LSLVQ
431
SRKAG
436
ITSAM
441
ATRTS
446
LKDEE
451
LKSHV
456
YKKTL
461
QALIY
466
PISCT
471
TPHNF
476
EVWTA
481
TTPTY
486
CYECE
491
GLLWG
496
IARQG
501
MRCSE
506
CGVKC
511
HEKCQ
516
DLLNA
521
DCLQR
526
AAEKS
531
CKHGA
536
EDRTQ
541
NIIMA
546
MKDRM
551
KIRER
556
NKPEI
561
FEVIR
566
DVFTV
571
NKAAH
576
VQQMK
581
TVKQS
586
VLDGT
591
SKWSA
596
KITIT
601
VVCAQ
606
GLQAK
611
DKTGS
616
SDPYV
621
TVQVS
626
KTKKR
631
TKTIF
636
GNLNP
641
VWEEK
646
FHFEC
651
HNSSD
656
RIKVR
661
VWDED
666
DDIKS
671
RVKQR
676
LKRES
681
DDFLG
686
QTIIE
691
VRTLS
696
GEMDV
701
WYNLE
706
KRTDK
711
SAVSG
716
AIRLQ
721
ISVEI
726
KGEEK
731
VAPYH
736
VQYTC
741
LHENL
746
FHYLT
751
DIQGS
756
GGVRI
761
PEARG
766
DDAWK
771
VYFDE
776
TAQEI
781
VDEFA
786
MRYGI
791
ESIYQ
796
AMTHF
801
ACLSS
806
KYMCP
811
GVPAV
816
MSTLL
821
ANINA
826
YYAHT
831
TASTN
836
VSASD
841
RFAAS
846
NFGKE
851
RFVKL
856
LDQLH
861
NSLRI
866
DLSTY
871
RNNFP
876
AGSPE
881
RLQDL
886
KSTVD
891
LLTSI
896
TFFRM
901
KVQEL
906
QSPPR
911
ASQVV
916
KDCVK
921
ACLNS
926
TYEYI
931
FNNCH
936
DLYSR
941
QYQLK
946
QELPP
951
EEQGP
956
SIRNL
961
DFWPK
966
LITLI
971
VSIIE
976
EDKNS
981
YTPVL
986
NQFPQ
991
ELNVG
996
KVSAE
1001
VMWHL
1006
FAQDM
1011
KYALE
1016
EHEKD
1021
HLCKS
1026
ADYMN
1031
LHFKV
1036
KWLHN
1041
EYVRD
1046
LPVLQ
1051
GQVPE
1056
YPAWF
1061
EQFVL
1066
QWLDE
1071
NEDVS
1076
LEFLR
1081
GALER
1086
DKKDG
1091
FQQTS
1096
EHALF
1101
SCSVV
1106
DVFTQ
1111
LNQSF
1116
EIIRK
1121
LECPD
1126
PSILA
1131
HYMRR
1136
FAKTI
1141
GKVLM
1146
QYADI
1151
LSKDF
1156
PAYCT
1161
KEKLP
1166
CILMN
1171
NVQQL
1176
RVQLE
1181
KMFEA
1186
MGGKE
1191
LDLEA
1196
ADSLK
1201
ELQVK
1206
LNTVL
1211
DELSM
1216
VFGNS
1221
FQVRI
1226
DECVR
1231
QMADI
1236
LGQVR
1241
GTGNA
1246
SPDAR
1251
ASAAQ
1256
DADSV
1261
LRPLM
1266
DFLDG
1271
NLTLF
1276
ATVCE
1281
KTVLK
1286
RVLKE
1291
LWRVV
1296
MNTME
1301
RMIVL
1306
PPLTD
1311
QTGTQ
1316
LIFTA
1321
AKELS
1326
HLSKL
1331
KDHMV
1336
REETR
1341
NLTPK
1346
QCAVL
1351
DLALD
1356
TIKQY
1361
FHAGG
1366
NGLKK
1371
TFLEK
1376
SPDLQ
1381
SLRYA
1386
LSLYT
1391
QTTDT
1396
LIKTF
1401
VRSQT
1406
TQGSG
1411
VDDPV
1416
GEVSI
1421
QVDLF
1426
THPGT
1431
GEHKV
1436
TVKVV
1441
AANDL
1446
KWQTA
1451
GMFRP
1456
FVEVT
1461
MVGPH
1466
QSDKK
1471
RKFTT
1476
KSKSN
1481
NWAPK
1486
YNETF
1491
HFLLG
1496
NEEGP
1501
ESYEL
1506
QICVK
1511
DYCFA
1516
REDRV
1521
LGLAV
1526
MPLRD
1531
VTAKG
1536
SCACW
1541
CPLGR
1546
KIHMD
1551
ETGLT
1556
ILRIL
1561
SQRSN
1566
DEVAR
1571
EFVKL
1576
KSESR
1581
STEEG
1586
S
1591
Mutation Information
DNA mutation:
None
Peptide Range:
1063 ~ 1087
Mut AA position:
1075 (13 in Wild Type peptide)
Alignment
Wild Type:
"AWFEQFVLQWLDENEDVSLEFLRGA
||||||||||||.||||||||||||
Mutant:
AWFEQFVLQWLDDNEDVSLEFLRGA"
Science, 2015
Immunogenicity of somatic mutations in human gastrointestinal cancersGene Name (from Reference) UNC13B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
TILs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay