Immunogenicity 13786
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CHRM2
Transcript ID
uc022ame.1
HLA INFO
C*12:03
TCR INFO
No TCR info found!
Full length protein sequence (466 aa)
MNNST
1
NSSNN
6
SLALT
11
SPYKT
16
FEVVF
21
IVLVA
26
GSLSL
31
VTIIG
36
NILVM
41
VSIKV
46
NRHLQ
51
TVNNY
56
FLFSL
61
ACADL
66
IIGVF
71
SMNLY
76
TLYTV
81
IGYWP
86
LGPVV
91
CDLWL
96
ALDYV
101
VSNAS
106
VMNLL
111
IISFD
116
RYFCV
121
TKPLT
126
YPVKR
131
TTKMA
136
GMMIA
141
AAWVL
146
SFILW
151
APAIL
156
FWQFI
161
VGVRT
166
VEDGE
171
CYIQF
176
FSNAA
181
VTFGT
186
AIAAF
191
YLPVI
196
IMTVL
201
YWHIS
206
RASKS
211
RIKKD
216
KKEPV
221
ANQDP
226
VSPSL
231
VQGRI
236
VKPNN
241
NNMPS
246
SDDGL
251
EHNKI
256
QNGKA
261
PRDPV
266
TENCV
271
QGEEK
276
ESSND
281
STSVS
286
AVASN
291
MRDDE
296
ITQDE
301
NTVST
306
SLGHS
311
KDENS
316
KQTCI
321
RIGTK
326
TPKSD
331
SCTPT
336
NTTVE
341
VVGSS
346
GQNGD
351
EKQNI
356
VARKI
361
VKMTK
366
QPAKK
371
KPPPS
376
REKKV
381
TRTIL
386
AILLA
391
FIITW
396
APYNV
401
MVLIN
406
TFCAP
411
CIPNT
416
VWTIG
421
YWLCY
426
INSTI
431
NPACY
436
ALCNA
441
TFKKT
446
FKHLL
451
MCHYK
456
NIGAT
461
R
466
Mutation Information
DNA mutation:
None
Peptide Range:
289 ~ 313
Mut AA position:
301 (13 in Wild Type peptide)
Alignment
Wild Type:
"VSAVASNMRDDEITQDENTVSTSLG
||||||||||||.||||||||||||
Mutant:
VSAVASNMRDDEKTQDENTVSTSLG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CHRM2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay