Immunogenicity 13854
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
NEFL
Transcript ID
uc003xee.4
HLA INFO
A*02:01
TCR INFO
No TCR info found!
Full length protein sequence (543 aa)
MSSFS
1
YEPYY
6
STSYK
11
RRYVE
16
TPRVH
21
ISSVR
26
SGYST
31
ARSAY
36
SSYSA
41
PVSSS
46
LSVRR
51
SYSSS
56
SGSLM
61
PSLEN
66
LDLSQ
71
VAAIS
76
NDLKS
81
IRTQE
86
KAQLQ
91
DLNDR
96
FASFI
101
ERVHE
106
LEQQN
111
KVLEA
116
ELLVL
121
RQKHS
126
EPSRF
131
RALYE
136
QEIRD
141
LRLAA
146
EDATN
151
EKQAL
156
QGERE
161
GLEET
166
LRNLQ
171
ARYEE
176
EVLSR
181
EDAEG
186
RLMEA
191
RKGAD
196
EAALA
201
RAELE
206
KRIDS
211
LMDEI
216
SFLKK
221
VHEEE
226
IAELQ
231
AQIQY
236
AQISV
241
EMDVT
246
KPDLS
251
AALKD
256
IRAQY
261
EKLAA
266
KNMQN
271
AEEWF
276
KSRFT
281
VLTES
286
AAKNT
291
DAVRA
296
AKDEV
301
SESRR
306
LLKAK
311
TLEIE
316
ACRGM
321
NEALE
326
KQLQE
331
LEDKQ
336
NADIS
341
AMQDT
346
INKLE
351
NELRT
356
TKSEM
361
ARYLK
366
EYQDL
371
LNVKM
376
ALDIE
381
IAAYR
386
KLLEG
391
EETRL
396
SFTSV
401
GSITS
406
GYSQS
411
SQVFG
416
RSAYG
421
GLQTS
426
SYLMS
431
TRSFP
436
SYYTS
441
HVQEE
446
QIEVE
451
ETIEA
456
AKAEE
461
AKDEP
466
PSEGE
471
AEEEE
476
KDKEE
481
AEEEE
486
AAEEE
491
EAAKE
496
ESEEA
501
KEEEE
506
GGEGE
511
EGEET
516
KEAEE
521
EEKKV
526
EGAGE
531
EQAAK
536
KKD
541
Mutation Information
DNA mutation:
None
Peptide Range:
51 ~ 75
Mut AA position:
63 (13 in Wild Type peptide)
Alignment
Wild Type:
"LSVRRSYSSSSGSLMPSLENLDLSQ
||||||||||||.||||||||||||
Mutant:
LSVRRSYSSSSGLLMPSLENLDLSQ"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) NEFL
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay