Immunogenicity 13887

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
GRHL2
Transcript ID
uc010mbu.3
HLA INFO
A*24:02
TCR INFO

No TCR info found!

T cell Tumor cell A*24:02
sequence
Full length protein sequence (625 aa)
MSQES
1
DNNKR
6
LVALV
11
PMPSD
16
PPFNT
21
RRAYT
26
SEDEA
31
WKSYL
36
ENPLT
41
AATKA
46
MMSIN
51
GDEDS
56
AAALG
61
LLYDY
66
YKVPR
71
DKRLL
76
SVSKA
81
SDSQE
86
DQEKR
91
NCLGT
96
SEAQS
101
NLSGG
106
ENRVQ
111
VLKTV
116
PVNLS
121
LNQDH
126
LENSK
131
REQYS
136
ISFPE
141
SSAII
146
PVSGI
151
TVVKA
156
EDFTP
161
VFMAP
166
PVHYP
171
RGDGE
176
EQRVV
181
IFEQT
186
QYDVP
191
SLATH
196
SAYLK
201
DDQRS
206
TPDST
211
YSESF
216
KDAAT
221
EKFRS
226
ASVGA
231
EEYMY
236
DQTSS
241
GTFQY
246
TLEAT
251
KSLRQ
256
KQGEG
261
PMTYL
266
NKGQF
271
YAITL
276
SETGD
281
NKCFR
286
HPISK
291
VRSVV
296
MVVFS
301
EDKNR
306
DEQLK
311
YWKYW
316
HSRQH
321
TAKQR
326
VLDIA
331
DYKES
336
FNTIG
341
NIEEI
346
AYNAV
351
SFTWD
356
VNEEA
361
KIFIT
366
VNCLS
371
TDFSS
376
QKGVK
381
GLPLM
386
IQIDT
391
YSYNN
396
RSNKP
401
IHRAY
406
CQIKV
411
FCDKG
416
AERKI
421
RDEER
426
KQNRK
431
KGKGQ
436
ASQTQ
441
CNSSS
446
DGKLA
451
AIPLQ
456
KKSDI
461
TYFKT
466
MPDLH
471
SQPVL
476
FIPDV
481
HFANL
486
QRTGQ
491
VYYNT
496
DDERE
501
GGSVL
506
VKRMF
511
RPMEE
516
EFGPV
521
PSKQM
526
KEEGT
531
KRVLL
536
YVRKE
541
TDDVF
546
DALML
551
KSPTV
556
KGLME
561
AISEK
566
YGLPV
571
EKIAK
576
LYKKS
581
KKGIL
586
VNMDD
591
NIIEH
596
YSNED
601
TFILN
606
MESMV
611
EGFKV
616
TLMEI
621
Mutation Information
DNA mutation:
None
Peptide Range:
395 ~ 419
Mut AA position:
407 (13 in Wild Type peptide)
Alignment
Wild Type:
"TYSYNNRSNKPIHRAYCQIKVFCDK
||||||||||||.||||||||||||
Mutant:
TYSYNNRSNKPIYRAYCQIKVFCDK"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay