Immunogenicity 13907
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DEPTOR
Transcript ID
uc003yow.4
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (409 aa)
MEEGG
1
STGSA
6
GSDSS
11
TSGSG
16
GAQQR
21
ELERM
26
AEVLV
31
TGEQL
36
RLRLH
41
EEKVI
46
KDRRH
51
HLKTY
56
PNCFV
61
AKELI
66
DWLIE
71
HKEAS
76
DRETA
81
IKLMQ
86
KLADR
91
GIIHH
96
VCDEH
101
KEFKD
106
VKLFY
111
RFRKD
116
DGTFP
121
LDNEV
126
KAFMR
131
GQRLY
136
EKLMS
141
PENTL
146
LQPRE
151
EEGVK
156
YERTF
161
MASEF
166
LDWLV
171
QEGEA
176
TTRKE
181
AEQLC
186
HRLME
191
HGIIQ
196
HVSNK
201
HPFVD
206
SNLLY
211
QFRMN
216
FRRRR
221
RLMEL
226
LNEKS
231
PSSQE
236
THDSP
241
FCLRK
246
QSHDN
251
RKSTS
256
FMSVS
261
PSKEI
266
KIVSA
271
VRRSS
276
MSSCG
281
SSGYF
286
SSSPT
291
LSSSP
296
PVLCN
301
PKSVL
306
KRPVT
311
SEELL
316
TPGAP
321
YARKT
326
FTIVG
331
DAVGW
336
GFVVR
341
GSKPC
346
HIQAV
351
DPSGP
356
AAAAG
361
MKVCQ
366
FVVSV
371
NGLNV
376
LHVDY
381
RTVSN
386
LILTG
391
PRTIV
396
MEVME
401
ELEC
406
Mutation Information
DNA mutation:
None
Peptide Range:
87 ~ 111
Mut AA position:
99 (13 in Wild Type peptide)
Alignment
Wild Type:
"KLMQKLADRGIIHHVCDEHKEFKDV
||||||||||||.||||||||||||
Mutant:
KLMQKLADRGIIYHVCDEHKEFKDV"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DEPDC6
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay