Immunogenicity 1394

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
MIA3
Transcript ID
ENST00000340535
HLA INFO
A*01:01
TCR INFO

No TCR info found!

T cell Tumor cell A*01:01
sequence
Full length protein sequence (785 aa)
MDSVP
1
ATVPS
6
IAATP
11
GDPEL
16
VGPLS
21
VLYAA
26
FIAKL
31
LELVA
36
TLPDD
41
VQPGP
46
DFYGL
51
PWKPV
56
FITAF
61
LGIAS
66
FAIFL
71
WRTVL
76
VVKDR
81
VYQVT
86
EQQIS
91
EKLKT
96
IMKEN
101
TELVQ
106
KLSNY
111
EQKIK
116
ESKKH
121
VQETR
126
KQNMI
131
LSDEA
136
IKYKD
141
KIKTL
146
EKNQE
151
ILDDT
156
AKNLR
161
VMLES
166
EREQN
171
VKNQD
176
LISEN
181
KKSIE
186
KLKDV
191
ISMNA
196
SEFSE
201
VQIAL
206
NEAKL
211
SEEKV
216
KSECH
221
RVQEE
226
NARLK
231
KKKEQ
236
LQQEI
241
EDWSK
246
LHAEL
251
SEQIK
256
SFEKS
261
QKDLE
266
VALTH
271
KDDNI
276
NALTN
281
CITQL
286
NLLEC
291
ESESE
296
GQNKG
301
GNDSD
306
ELANG
311
EVGGD
316
RNEKM
321
KNQIK
326
QMMDV
331
SRTQT
336
AISVV
341
EEDLK
346
LLQLK
351
LRASV
356
STKCN
361
LEDQV
366
KKLED
371
DRNSL
376
QAAKA
381
GLEDE
386
CKTLR
391
QKVEI
396
LNELY
401
QQKEM
406
ALQKK
411
LSQEE
416
YERQE
421
REHRL
426
SAADE
431
KAVSA
436
AEEVK
441
TYKRR
446
IEEME
451
DELQK
456
TERSF
461
KNQIA
466
THEKK
471
AHENW
476
LKARA
481
AERAI
486
AEEKR
491
EAANL
496
RHKLL
501
ELTQK
506
MAMLQ
511
EEPVI
516
VKPMP
521
GKPNT
526
QNPPR
531
RGPLS
536
QNGSF
541
GPSPV
546
SGGEC
551
SPPLT
556
VEPPV
561
RPLSA
566
TLNRR
571
DMPRS
576
EFGSV
581
DGPLP
586
HPRWS
591
AEASG
596
KPSPS
601
DPGSG
606
TATMM
611
NSSSR
616
GSSPT
621
RVLDE
626
GKVNM
631
APKGP
636
PPFPG
641
VPLMS
646
TPMGG
651
PVPPP
656
IRYGP
661
PPQLC
666
GPFGP
671
RPLPP
676
PFGPG
681
MRPPL
686
GLREF
691
APGVP
696
PGRRD
701
LPLHP
706
RGFLP
711
GHAPF
716
RPLGS
721
LGPRE
726
YFIPG
731
TRLPP
736
PTHGP
741
QEYPP
746
PPAVR
751
DLLPS
756
GSRDE
761
PPPAS
766
QSTSQ
771
DCSQA
776
LKQSP
781
Mutation Information
DNA mutation:
None
Peptide Range:
104 ~ 128
Mut AA position:
116 (13 in Wild Type peptide)
Alignment
Wild Type:
"ENTELVQKLSNYEQKIKESKKHVQE
||||||||||||.||||||||||||
Mutant:
ENTELVQKLSNYDQKIKESKKHVQE"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) MIA3

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay