Immunogenicity 1396

Sample ID
3942
Response
Negative
Tumor Type
Rectal cancer
Gene Symbol
SORBS2
Transcript ID
ENST00000319454

HLA INFO
DRB*07:01
TCR INFO

No TCR info found!

T cell Tumor cell DRB*07:01
Full length protein sequence (636 aa)
MNTGR
1
DSQSP
6
DSAKG
11
FRSVR
16
PNLQD
21
KRSPT
26
QSQIT
31
VNGNS
36
GGAVS
41
PMSYY
46
QRPFS
51
PSAYS
56
LPASL
61
NSSIV
66
MQHGT
71
SLDST
76
DTYPQ
81
HAQSL
86
DGTTS
91
SSIPL
96
YRSSE
101
EEKRV
106
TVIKA
111
PHYPG
116
IGPVD
121
ESGIP
126
TAIRT
131
TVDRP
136
KDWYK
141
TMFKQ
146
IHMVH
151
KPDDD
156
TDMYN
161
TPYTY
166
NAGLY
171
NPPYS
176
AQSHP
181
AAKTQ
186
TYRPL
191
SKSHS
196
DNSPN
201
AFKDA
206
SSPVP
211
PPHVP
216
PPVPP
221
LRPRD
226
RSSTE
231
KHDWD
236
PPDRK
241
VDTRK
246
FRSEP
251
RSIFE
256
YEPGK
261
SSILQ
266
HERPP
271
PLPTT
276
PTPVP
281
REPGR
286
KPLSS
291
SRLGE
296
VTGSP
301
SPPPR
306
SGAPT
311
PSSRA
316
PALSP
321
TRPPK
326
KPLDY
331
VQDHS
336
SGVFN
341
EASLY
346
QSSID
351
RSLER
356
PMSSA
361
SMASD
366
FRKRR
371
KSEPA
376
VGPPR
381
GLGDQ
386
SASRT
391
SPGRV
396
DLPGS
401
STTLT
406
KSFTS
411
SSPSS
416
PSRAK
421
DRESP
426
RSYSS
431
TLTDM
436
GRSAP
441
RERRG
446
TPEKE
451
KLPAK
456
AVYDF
461
KAQTS
466
KELSF
471
KKGDT
476
VYILR
481
KIDQN
486
WYEGE
491
HHGRV
496
GIFPI
501
SYVEK
506
LTPPE
511
KAQPA
516
RPPPP
521
AQPGE
526
IGEAI
531
AKYNF
536
NADTN
541
VELSL
546
RKGDR
551
VILLK
556
RVDQN
561
WYEGK
566
IPGTN
571
RQGIF
576
PVSYV
581
EVVKK
586
NTKGA
591
EDYPD
596
PPIPH
601
SYSSD
606
RIHSL
611
SSNKP
616
QRPVF
621
THENI
626
QGGGE
631
P
636
Mutation Information
DNA mutation:
None
Peptide Range:
623 ~ 636
Mut AA position:
635 (13 in Wild Type peptide)
Alignment
Wild Type:
"PVFTHENIQGGGEP
||||||||||||.|
Mutant:
PVFTHENIQGGGVP"

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) ENSG00000154556

Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay