Immunogenicity 13963
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TDRD7
Transcript ID
uc004axj.3
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (1098 aa)
MLEGD
1
LVSKM
6
LRAVL
11
QSHKN
16
GVALP
21
RLQGE
26
YRSLT
31
GDWIP
36
FKQLG
41
FPTLE
46
AYLRS
51
VPAVV
56
RIETS
61
RSGEI
66
TCYAM
71
ACTET
76
ARIAQ
81
LVARQ
86
RSSKR
91
KTGRQ
96
VNCQM
101
RVKKT
106
MPFFL
111
EGKPK
116
ATLRQ
121
PGFAS
126
NFSVG
131
KKPNP
136
APLRD
141
KGNSV
146
GVKPD
151
AEMSP
156
YMLHT
161
TLGNE
166
AFKDI
171
PVQRH
176
VTMST
181
NNRFS
186
PKASL
191
QPPLQ
196
MHLSR
201
TSTKE
206
MSDNL
211
NQTVE
216
KPNVK
221
PPASY
226
TYKMD
231
EVQNR
236
IKEIL
241
NKHNN
246
GIWIS
251
KLPHF
256
YKELY
261
KEDLN
266
QGILQ
271
QFEHW
276
PHICT
281
VEKPC
286
SGGQD
291
LLLYP
296
AKRKQ
301
LLRSE
306
LDTEK
311
VPLSP
316
LPGPK
321
QTPPL
326
KGCPT
331
VMAGD
336
FKEKV
341
ADLLV
346
KYTSG
351
LWASA
356
LPKAF
361
EEMYK
366
VKFPE
371
DALKN
376
LASLS
381
DVCSI
386
DYISG
391
NPQKA
396
ILYAK
401
LPLPT
406
DKIQK
411
DAGQA
416
HGDND
421
IKAMV
426
EQEYL
431
QVEES
436
IAESA
441
NTFME
446
DITVP
451
PLMIP
456
TEASP
461
SVLVV
466
ELSNT
471
NEVVI
476
RYVGK
481
DYSAA
486
QELME
491
DEMKE
496
YYSKN
501
PKITP
506
VQAVN
511
VGQLL
516
AVNAE
521
EDAWL
526
RAQVI
531
STEEN
536
KIKVC
541
YVDYG
546
FSENV
551
EKSKA
556
YKLNP
561
KFCSL
566
SFQAT
571
KCKLA
576
GLEVL
581
SDDPD
586
LVKVV
591
ESLTC
596
GKIFA
601
VEILD
606
KADIP
611
LVVLY
616
DTSGE
621
DDINI
626
NATCL
631
KAICD
636
KSLEV
641
HLQVD
646
AMYTN
651
VKVTN
656
ICSDG
661
TLYCQ
666
VPCKG
671
LNKLS
676
DLLRK
681
IEDYF
686
HCKHM
691
TSECF
696
VSLPF
701
CGKIC
706
LFHCK
711
GKWLR
716
VEITN
721
VHSSR
726
ALDVQ
731
FLDSG
736
TVTSV
741
KVSEL
746
REIPP
751
RFLQE
756
MIAIP
761
PQAIK
766
CCLAD
771
LPQSI
776
GMWTP
781
DAVLW
786
LRDSV
791
LNCSD
796
CSIKV
801
TKVDE
806
TRGIA
811
HVYLF
816
TPKNF
821
PDPHR
826
SINRQ
831
ITNAD
836
LWKHQ
841
KDVFL
846
SAISS
851
GADSP
856
NSKNG
861
NMPMS
866
GNTGE
871
NFRKN
876
LTDVI
881
KKSMV
886
DHTSA
891
FSTEE
896
LPPPV
901
HLSKP
906
GEHMD
911
VYVPV
916
ACHPG
921
YFVIQ
926
PWQEI
931
HKLEV
936
LMEEM
941
ILYYS
946
VSEER
951
HIAVE
956
KDQVY
961
AAKVE
966
NKWHR
971
VLLKG
976
ILTNG
981
LVSVY
986
ELDYG
991
KHELV
996
NIRKV
1001
QPLVD
1006
MFRKL
1011
PFQAV
1016
TAQLA
1021
GVKCN
1026
QWSEE
1031
ASMVF
1036
RNHVE
1041
KKPLV
1046
ALVQT
1051
VIENA
1056
NPWDR
1061
KVVVY
1066
LVDTS
1071
LPDTD
1076
TWIHD
1081
FMSEY
1086
LIELS
1091
KVN
1096
Mutation Information
DNA mutation:
None
Peptide Range:
47 ~ 71
Mut AA position:
59 (13 in Wild Type peptide)
Alignment
Wild Type:
"PTLEAYLRSVPAVVRIETSRSGEIT
||||||||||||.||||||||||||
Mutant:
PTLEAYLRSVPAGVRIETSRSGEIT"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) TDRD7
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay