Immunogenicity 13979

summary
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PAPPA
Transcript ID
uc004bjn.3
HLA INFO
C*05:01
TCR INFO

No TCR info found!

T cell Tumor cell C*05:01
sequence
Full length protein sequence (1627 aa)
MRLWS
1
WVLHL
6
GLLSA
11
ALGCG
16
LAERP
21
RRARR
26
DPRAG
31
RPPRP
36
AAGPA
41
TCATR
46
AARGR
51
RASPP
56
PPPPP
61
GGAWE
66
AVRVP
71
RRRQQ
76
REARG
81
ATEEP
86
SPPSR
91
ALYFS
96
GRGEQ
101
LRLRA
106
DLELP
111
RDAFT
116
LQVWL
121
RAEGG
126
QRSPA
131
VITGL
136
YDKCS
141
YISRD
146
RGWVV
151
GIHTI
156
SDQDN
161
KDPRY
166
FFSLK
171
TDRAR
176
QVTTI
181
NAHRS
186
YLPGQ
191
WVYLA
196
ATYDG
201
QFMKL
206
YVNGA
211
QVATS
216
GEQVG
221
GIFSP
226
LTQKC
231
KVLML
236
GGSAL
241
NHNYR
246
GYIEH
251
FSLWK
256
VARTQ
261
REILS
266
DMETH
271
GAHTA
276
LPQLL
281
LQENW
286
DNVKH
291
AWSPM
296
KDGSS
301
PKVEF
306
SNAHG
311
FLLDT
316
SLEPP
321
LCGQT
326
LCDNT
331
EVIAS
336
YNQLS
341
SFRQP
346
KVVRY
351
RVVNL
356
YEDDH
361
KNPTV
366
TREQV
371
DFQHH
376
QLAEA
381
FKQYN
386
ISWEL
391
DVLEV
396
SNSSL
401
RRRLI
406
LANCD
411
ISKIG
416
DENCD
421
PECNH
426
TLTGH
431
DGGDC
436
RHLRH
441
PAFVK
446
KQHNG
451
VCDMD
456
CNYER
461
FNFDG
466
GECCD
471
PEITN
476
VTQTC
481
FDPDS
486
PHRAY
491
LDVNE
496
LKNIL
501
KLDGS
506
THLNI
511
FFAKS
516
SEEEL
521
AGVAT
526
WPWDK
531
EALMH
536
LGGIV
541
LNPSF
546
YGMPG
551
HTHTM
556
IHEIG
561
HSLGL
566
YHVFR
571
GISEI
576
QSCSD
581
PCMET
586
EPSFE
591
TGDLC
596
NDTNP
601
APKHK
606
SCGDP
611
GPGND
616
TCGFH
621
SFFNT
626
PYNNF
631
MSYAD
636
DDCTD
641
SFTPN
646
QVARM
651
HCYLD
656
LVYQG
661
WQPSR
666
KPAPV
671
ALAPQ
676
VLGHT
681
TDSVT
686
LEWFP
691
PIDGH
696
FFERE
701
LGSAC
706
HLCLE
711
GRILV
716
QYASN
721
ASSPM
726
PCSPS
731
GHWSP
736
REAEG
741
HPDVE
746
QPCKS
751
SVRTW
756
SPNSA
761
VNPHT
766
VPPAC
771
PEPQG
776
CYLEL
781
EFLYP
786
LVPES
791
LTIWV
796
TFVST
801
DWDSS
806
GAVND
811
IKLLA
816
VSGKN
821
ISLGP
826
QNVFC
831
DVPLT
836
IRLWD
841
VGEEV
846
YGIQI
851
YTLDE
856
HLEID
861
AAMLT
866
STADT
871
PLCLQ
876
CKPLK
881
YKVVR
886
DPPLQ
891
MDVAS
896
ILHLN
901
RKFVD
906
MDLNL
911
GSVYQ
916
YWVIT
921
ISGTE
926
ESEPS
931
PAVTY
936
IHGSG
941
YCGDG
946
IIQKD
951
QGEQC
956
DDMNK
961
INGDG
966
CSLFC
971
RQEVS
976
FNCID
981
EPSRC
986
YFHDG
991
DGVCE
996
EFEQK
1001
TSIKD
1006
CGVYT
1011
PQGFL
1016
DQWAS
1021
NASVS
1026
HQDQQ
1031
CPGWV
1036
IIGQP
1041
AASQV
1046
CRTKV
1051
IDLSE
1056
GISQH
1061
AWYPC
1066
TISYP
1071
YSQLA
1076
QTTFW
1081
LRAYF
1086
SQPMV
1091
AAAVI
1096
VHLVT
1101
DGTYY
1106
GDQKQ
1111
ETISV
1116
QLLDT
1121
KDQSH
1126
DLGLH
1131
VLSCR
1136
NNPLI
1141
IPVVH
1146
DLSQP
1151
FYHSQ
1156
AVRVS
1161
FSSPL
1166
VAISG
1171
VALRS
1176
FDNFD
1181
PVTLS
1186
SCQRG
1191
ETYSP
1196
AEQSC
1201
VHFAC
1206
EKTDC
1211
PELAV
1216
ENASL
1221
NCSSS
1226
DRYHG
1231
AQCTV
1236
SCRTG
1241
YVLQI
1246
RRDDE
1251
LIKSQ
1256
TGPSV
1261
TVTCT
1266
EGKWN
1271
KQVAC
1276
EPVDC
1281
SIPDH
1286
HQVYA
1291
ASFSC
1296
PEGTT
1301
FGSQC
1306
SFQCR
1311
HPAQL
1316
KGNNS
1321
LLTCM
1326
EDGLW
1331
SFPEA
1336
LCELM
1341
CLAPP
1346
PVPNA
1351
DLQTA
1356
RCREN
1361
KHKVG
1366
SFCKY
1371
KCKPG
1376
YHVPG
1381
SSRKS
1386
KKRAF
1391
KTQCT
1396
QDGSW
1401
QEGAC
1406
VPVTC
1411
DPPPP
1416
KFHGL
1421
YQCTN
1426
GFQFN
1431
SECRI
1436
KCEDS
1441
DASQG
1446
LGSNV
1451
IHCRK
1456
DGTWN
1461
GSFHV
1466
CQEMQ
1471
GQCSV
1476
PNELN
1481
SNLKL
1486
QCPDG
1491
YAIGS
1496
ECATS
1501
CLDHN
1506
SESII
1511
LPMNV
1516
TVRDI
1521
PHWLN
1526
PTRVE
1531
RVVCT
1536
AGLKW
1541
YPHPA
1546
LIHCV
1551
KGCEP
1556
FMGDN
1561
YCDAI
1566
NNRAF
1571
CNYDG
1576
GDCCT
1581
STVKT
1586
KKVTP
1591
FPMSC
1596
DLQGD
1601
CACRD
1606
PQAQE
1611
HSRKD
1616
LRGYS
1621
HG
1626
Mutation Information
DNA mutation:
None
Peptide Range:
139 ~ 163
Mut AA position:
151 (13 in Wild Type peptide)
Alignment
Wild Type:
"GLYDKCSYISRDRGWVVGIHTISDQ
||||||||||||.||||||||||||
Mutant:
GLYDKCSYISRDQGWVVGIHTISDQ"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

COS7

Assay

IFNg ELISPOT assay