Immunogenicity 1403

summary
Sample ID
3971
Response
Negative
Tumor Type
Colon cancer
Gene Symbol
SFXN2
Transcript ID
ENST00000369893
HLA INFO
DQA*01:03 / DQB*02:05
TCR INFO

No TCR info found!

T cell Tumor cell { DQA*01:03 DQB*02:05
sequence
Full length protein sequence (322 aa)
MEADL
1
SGFNI
6
DAPRW
11
DQRTF
16
LGRVK
21
HFLNI
26
TDPRT
31
VFVSE
36
RELDW
41
AKVMV
46
EKSRM
51
GVVPP
56
GTQVE
61
QLLYA
66
KKLYD
71
SAFHP
76
DTGEK
81
MNVIG
86
RMSFQ
91
LPGGM
96
IITGF
101
MLQFY
106
RTMPA
111
VIFWQ
116
WVNQS
121
FNALV
126
NYTNR
131
NAASP
136
TSVRQ
141
MALSY
146
FTATT
151
TAVAT
156
AVGMN
161
MLTKK
166
APPLV
171
GRWVP
176
FAAVA
181
AANCV
186
NIPMM
191
RQQEL
196
IKGIC
201
VKDRN
206
ENEIG
211
HSRRA
216
AAIGI
221
TQVVI
226
SRITM
231
SAPGM
236
ILLPV
241
IMERL
246
EKLHF
251
MQKVK
256
VLHAP
261
LQVML
266
SGCFL
271
IFMVP
276
VACGL
281
FPQKC
286
ELPVS
291
YLEPK
296
LQDTI
301
KAKYG
306
ELEPY
311
VYFNK
316
GL
321
Mutation Information
DNA mutation:
None
Peptide Range:
125 ~ 149
Mut AA position:
137 (13 in Wild Type peptide)
Alignment
Wild Type:
"SFNALVNYTNRNAASPTSVRQMALS
||||||||||||.||||||||||||
Mutant:
SFNALVNYTNRNTASPTSVRQMALS"
reference

Science, 2015

Immunogenicity of somatic mutations in human gastrointestinal cancers

Gene Name (from Reference) SFXN2

clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

TILs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay