Immunogenicity 14094
Sample ID
3998
Response
Negative
Tumor Type
Melanoma
Gene Symbol
CHRDL1
Transcript ID
uc011mss.2
HLA INFO
B*15:01
TCR INFO
No TCR info found!
Full length protein sequence (378 aa)
MRKKW
1
KMGGM
6
KYIFS
11
LLFFL
16
LLEGG
21
KTEQV
26
KHSET
31
YCMFQ
36
DKKYR
41
VGERW
46
HPYLE
51
PYGLV
56
YCVNC
61
ICSEN
66
GNVLC
71
SRVRC
76
PNVHC
81
LSPVH
86
IPHLC
91
CPRCP
96
GDGEL
101
SWEHS
106
DGDIF
111
RQPAN
116
REARH
121
SYHRS
126
HYDPP
131
PSRQA
136
GGLSR
141
FPGAR
146
SHRGA
151
LMDSQ
156
QASGT
161
IVQIV
166
INNKH
171
KHGQV
176
CVSNG
181
KTYSH
186
GESWH
191
PNLRA
196
FGIVE
201
CVLCT
206
CNVTK
211
QECKK
216
IHCPN
221
RYPCK
226
YPQKI
231
DGKCC
236
KVCPG
241
KKAKE
246
ELPGQ
251
SFDNK
256
GYFCG
261
EETMP
266
VYESV
271
FMEDG
276
ETTRK
281
IALET
286
ERPPQ
291
VEVHV
296
WTIRK
301
GILQH
306
FHIEK
311
ISKRM
316
FEELP
321
HFKLV
326
TRTTL
331
SQWKI
336
FTEGE
341
AQISQ
346
MCSSR
351
VCRTE
356
LEDLV
361
KVLYL
366
ERSEK
371
GHC
376
Mutation Information
DNA mutation:
None
Peptide Range:
214 ~ 238
Mut AA position:
226 (13 in Wild Type peptide)
Alignment
Wild Type:
"TKQECKKIHCPNRYPCKYPQKIDGK
||||||||||||.||||||||||||
Mutant:
TKQECKKIHCPNQYPCKYPQKIDGK"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) CHRDL1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
COS7
Assay
IFNg ELISPOT assay