Immunogenicity 14114
Sample ID
3926
Response
Negative
Tumor Type
Melanoma
Gene Symbol
L1CAM
Transcript ID
uc031tks.1
HLA INFO
B*08:01
TCR INFO
No TCR info found!
Full length protein sequence (1257 aa)
MVVAL
1
RYVWP
6
LLLCS
11
PCLLI
16
QIPEE
21
YEGHH
26
VMEPP
31
VITEQ
36
SPRRL
41
VVFPT
46
DDISL
51
KCEAS
56
GKPEV
61
QFRWT
66
RDGVH
71
FKPKE
76
ELGVT
81
VYQSP
86
HSGSF
91
TITGN
96
NSNFA
101
QRFQG
106
IYRCF
111
ASNKL
116
GTAMS
121
HEIRL
126
MAEGA
131
PKWPK
136
ETVKP
141
VEVEE
146
GESVV
151
LPCNP
156
PPSAE
161
PLRIY
166
WMNSK
171
ILHIK
176
QDERV
181
TMGQN
186
GNLYF
191
ANVLT
196
SDNHS
201
DYICH
206
AHFPG
211
TRTII
216
QKEPI
221
DLRVK
226
ATNSM
231
IDRKP
236
RLLFP
241
TNSSS
246
HLVAL
251
QGQPL
256
VLECI
261
AEGFP
266
TPTIK
271
WLRPS
276
GPMPA
281
DRVTY
286
QNHNK
291
TLQLL
296
KVGEE
301
DDGEY
306
RCLAE
311
NSLGS
316
ARHAY
321
YVTVE
326
AAPYW
331
LHKPQ
336
SHLYG
341
PGETA
346
RLDCQ
351
VQGRP
356
QPEVT
361
WRING
366
IPVEE
371
LAKDQ
376
KYRIQ
381
RGALI
386
LSNVQ
391
PSDTM
396
VTQCE
401
ARNRH
406
GLLLA
411
NAYIY
416
VVQLP
421
AKILT
426
ADNQT
431
YMAVQ
436
GSTAY
441
LLCKA
446
FGAPV
451
PSVQW
456
LDEDG
461
TTVLQ
466
DERFF
471
PYANG
476
TLGIR
481
DLQAN
486
DTGRY
491
FCLAA
496
NDQNN
501
VTIMA
506
NLKVK
511
DATQI
516
TQGPR
521
STIEK
526
KGSRV
531
TFTCQ
536
ASFDP
541
SLQPS
546
ITWRG
551
DGRDL
556
QELGD
561
SDKYF
566
IEDGR
571
LVIHS
576
LDYSD
581
QGNYS
586
CVAST
591
ELDVV
596
ESRAQ
601
LLVVG
606
SPGPV
611
PRLVL
616
SDLHL
621
LTQSQ
626
VRVSW
631
SPAED
636
HNAPI
641
EKYDI
646
EFEDK
651
EMAPE
656
KWYSL
661
GKVPG
666
NQTST
671
TLKLS
676
PYVHY
681
TFRVT
686
AINKY
691
GPGEP
696
SPVSE
701
TVVTP
706
EAAPE
711
KNPVD
716
VKGEG
721
NETTN
726
MVITW
731
KPLRW
736
MDWNA
741
PQVQY
746
RVQWR
751
PQGTR
756
GPWQE
761
QIVSD
766
PFLVV
771
SNTST
776
FVPYE
781
IKVQA
786
VNSQG
791
KGPEP
796
QVTIG
801
YSGED
806
YPQAI
811
PELEG
816
IEILN
821
SSAVL
826
VKWRP
831
VDLAQ
836
VKGHL
841
RGYNV
846
TYWRE
851
GSQRK
856
HSKRH
861
IHKDH
866
VVVPA
871
NTTSV
876
ILSGL
881
RPYSS
886
YHLEV
891
QAFNG
896
RGSGP
901
ASEFT
906
FSTPE
911
GVPGH
916
PEALH
921
LECQS
926
NTSLL
931
LRWQP
936
PLSHN
941
GVLTG
946
YVLSY
951
HPLDE
956
GGKGQ
961
LSFNL
966
RDPEL
971
RTHNL
976
TDLSP
981
HLRYR
986
FQLQA
991
TTKEG
996
PGEAI
1001
VREGG
1006
TMALS
1011
GISDF
1016
GNISA
1021
TAGEN
1026
YSVVS
1031
WVPKE
1036
GQCNF
1041
RFHIL
1046
FKALG
1051
EEKGG
1056
ASLSP
1061
QYVSY
1066
NQSSY
1071
TQWDL
1076
QPDTD
1081
YEIHL
1086
FKERM
1091
FRHQM
1096
AVKTN
1101
GTGRV
1106
RLPPA
1111
GFATE
1116
GWFIG
1121
FVSAI
1126
ILLLL
1131
VLLIL
1136
CFIKR
1141
SKGGK
1146
YSVKD
1151
KEDTQ
1156
VDSEA
1161
RPMKD
1166
ETFGE
1171
YRSLE
1176
SDNEE
1181
KAFGS
1186
SQPSL
1191
NGDIK
1196
PLGSD
1201
DSLAD
1206
YGGSV
1211
DVQFN
1216
EDGSF
1221
IGQYS
1226
GKKEK
1231
EAAGG
1236
NDSSG
1241
ATSPI
1246
NPAVA
1251
LE
1256
Mutation Information
DNA mutation:
None
Peptide Range:
360 ~ 384
Mut AA position:
372 (13 in Wild Type peptide)
Alignment
Wild Type:
"PQPEVTWRINGIPVEELAKDQKYRI
||||||||||||.||||||||||||
Mutant:
PQPEVTWRINGISVEELAKDQKYRI"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) L1CAM
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay