Immunogenicity 14160

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
FLNC
Transcript ID
NM_001458
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (2725 aa)
MMNNS
1
GYSDA
6
GLGLG
11
DETDE
16
MPSTE
21
KDLAE
26
DAPWK
31
KIQQN
36
TFTRW
41
CNEHL
46
KCVGK
51
RLTDL
56
QRDLS
61
DGLRL
66
IALLE
71
VLSQK
76
RMYRK
81
FHPRP
86
NFRQM
91
KLENV
96
SVALE
101
FLERE
106
HIKLV
111
SIDSK
116
AIVDG
121
NLKLI
126
LGLIW
131
TLILH
136
YSISM
141
PMWED
146
EDDED
151
ARKQT
156
PKQRL
161
LGWIQ
166
NKVPQ
171
LPITN
176
FNRDW
181
QDGKA
186
LGALV
191
DNCAP
196
GLCPD
201
WEAWD
206
PNQPV
211
ENARE
216
AMQQA
221
DDWLG
226
VPQVI
231
APEEI
236
VDPNV
241
DEHSV
246
MTYLS
251
QFPKA
256
KLKPG
261
APVRS
266
KQLNP
271
KKAIA
276
YGPGI
281
EPQGN
286
TVLQP
291
AHFTV
296
QTVDA
301
GVGEV
306
LVYIE
311
DPEGH
316
TEEAK
321
VVPNN
326
DKDRT
331
YAVSY
336
VPKVA
341
GLHKV
346
TVLFA
351
GQNIE
356
RSPFE
361
VNVGM
366
ALGDA
371
NKVSA
376
RGPGL
381
EPVGN
386
VANKP
391
TYFDI
396
YTAGA
401
GTGDV
406
AVVIV
411
DPQGR
416
RDTVE
421
VALED
426
KGDST
431
FRCTY
436
RPAME
441
GPHTV
446
HVAFA
451
GAPIT
456
RSPFP
461
VHVSE
466
ACNPN
471
ACRAS
476
GRGLQ
481
PKGVR
486
VKEVA
491
DFKVF
496
TKGAG
501
SGELK
506
VTVKG
511
PKGTE
516
EPVKV
521
REAGD
526
GVFEC
531
EYYPV
536
VPGKY
541
VVTIT
546
WGGYA
551
IPRSP
556
FEVQV
561
SPEAG
566
VQKVR
571
AWGPG
576
LETGQ
581
VGKSA
586
DFVVE
591
AIGTE
596
VGTLG
601
FSIEG
606
PSQAK
611
IECDD
616
KGDGS
621
CDVRY
626
WPTEP
631
GEYAV
636
HVICD
641
DEDIR
646
DSPFI
651
AHILP
656
APPDC
661
FPDKV
666
KAFGP
671
GLEPT
676
GCIVD
681
KPAEF
686
TIDAR
691
AAGKG
696
DLKLY
701
AQDAD
706
GCPID
711
IKVIP
716
NGDGT
721
FRCSY
726
VPTKP
731
IKHTI
736
IISWG
741
GVNVP
746
KSPFR
751
VNVGE
756
GSHPE
761
RVKVY
766
GPGVE
771
KTGLK
776
ANEPT
781
YFTVD
786
CSEAG
791
QGDVS
796
IGIKC
801
APGVV
806
GPAEA
811
DIDFD
816
IIKND
821
NDTFT
826
VKYTP
831
PGAGR
836
YTIMV
841
LFANQ
846
EIPAS
851
PFHIK
856
VDPSH
861
DASKV
866
KAEGP
871
GLNRT
876
GVEVG
881
KPTHF
886
TVLTK
891
GAGKA
896
KLDVQ
901
FAGTA
906
KGEVV
911
RDFEI
916
IDNHD
921
YSYTV
926
KYTAV
931
QQGNM
936
AVTVT
941
YGGDP
946
VPKSP
951
FVVNV
956
APPLD
961
LSKIK
966
VQGLN
971
SKVAV
976
GQEQA
981
FSVNT
986
RGAGG
991
QGQLD
996
VRMTS
1001
PSRRP
1006
IPCKL
1011
EPGGG
1016
AEAQA
1021
VRYMP
1026
PEEGP
1031
YKVDI
1036
TYDGH
1041
PVPGS
1046
PFAVE
1051
GVLPP
1056
DPSKV
1061
CAYGP
1066
GLKGG
1071
LVGTP
1076
APFSI
1081
DTKGA
1086
GTGGL
1091
GLTVE
1096
GPCEA
1101
KIECQ
1106
DNGDG
1111
SCAVS
1116
YLPTE
1121
PGEYT
1126
INILF
1131
AEAHI
1136
PGSPF
1141
KATIR
1146
PVFDP
1151
SKVRA
1156
SGPGL
1161
ERGKV
1166
GEAAT
1171
FTVDC
1176
SEAGE
1181
AELTI
1186
EILSD
1191
AGVKA
1196
EVLIH
1201
NNADG
1206
TYHIT
1211
YSPAF
1216
PGTYT
1221
ITIKY
1226
GGHPV
1231
PKFPT
1236
RVHVQ
1241
PAVDT
1246
SGVKV
1251
SGPGV
1256
EPHGV
1261
LREVT
1266
TEFTV
1271
DARSL
1276
TATGG
1281
NHVTA
1286
RVLNP
1291
SGAKT
1296
DTYVT
1301
DNGDG
1306
TYRVQ
1311
YTAYE
1316
EGVHL
1321
VEVLY
1326
DEVAV
1331
PKSPF
1336
RVGVT
1341
EGCDP
1346
TRVRA
1351
FGPGL
1356
EGGLV
1361
NKANR
1366
FTVET
1371
RGAGT
1376
GGLGL
1381
AIEGP
1386
SEAKM
1391
SCKDN
1396
KDGSC
1401
TVEYI
1406
PFTPG
1411
DYDVN
1416
ITFGG
1421
RPIPG
1426
SPFRV
1431
PVKDV
1436
VDPGK
1441
VKCSG
1446
PGLGA
1451
GVRAR
1456
VPQTF
1461
TVDCS
1466
QAGRA
1471
PLQVA
1476
VLGPT
1481
GVAEP
1486
VEVRD
1491
NGDGT
1496
HTVHY
1501
TPATD
1506
GPYTV
1511
AVKYA
1516
DQEVP
1521
RSPFK
1526
IKVLP
1531
AHDAS
1536
KVRAS
1541
GPGLN
1546
ASGIP
1551
ASLPV
1556
EFTID
1561
ARDAG
1566
EGLLT
1571
VQILD
1576
PEGKP
1581
KKANI
1586
RDNGD
1591
GTYTV
1596
SYLPD
1601
MSGRY
1606
TITIK
1611
YGGDE
1616
IPYSP
1621
FRIHA
1626
LPTGD
1631
ASKCL
1636
VTVSI
1641
GGHGL
1646
GACLG
1651
PRIQI
1656
GQETV
1661
ITVDA
1666
KAAGE
1671
GKVTC
1676
TVSTP
1681
DGAEL
1686
DVDVV
1691
ENHDG
1696
TFDIY
1701
YTAPE
1706
PGKYV
1711
ITIRF
1716
GGEHI
1721
PNSPF
1726
HVLAC
1731
DPLPH
1736
EEEPS
1741
EVPQL
1746
RQPYA
1751
PPRPG
1756
ARPTH
1761
WATEE
1766
PVVPV
1771
EPMES
1776
MLRPF
1781
NLVIP
1786
FAVQK
1791
GELTG
1796
EVRMP
1801
SGKTA
1806
RPNIT
1811
DNKDG
1816
TITVR
1821
YAPTE
1826
KGLHQ
1831
MGIKY
1836
DGNHI
1841
PGSPL
1846
QFYVD
1851
AINSR
1856
HVSAY
1861
GPGLS
1866
HGMVN
1871
KPATF
1876
TIVTK
1881
DAGEG
1886
GLSLA
1891
VEGPS
1896
KAEIT
1901
CKDNK
1906
DGTCT
1911
VSYLP
1916
TAPGD
1921
YSIIV
1926
RFDDK
1931
HIPGS
1936
PFTAK
1941
ITGDD
1946
SMRTS
1951
QLNVG
1956
TSTDV
1961
SLKIT
1966
ESDLS
1971
QLTAS
1976
IRAPS
1981
GNEEP
1986
CLLKR
1991
LPNRH
1996
IGISF
2001
TPKEV
2006
GEHVV
2011
SVRKS
2016
GKHVT
2021
NSPFK
2026
ILVGP
2031
SEIGD
2036
ASKVR
2041
VWGKG
2046
LSEGH
2051
TFQVA
2056
EFIVD
2061
TRNAG
2066
YGGLG
2071
LSIEG
2076
PSKVD
2081
INCED
2086
MEDGT
2091
CKVTY
2096
CPTEP
2101
GTYII
2106
NIKFA
2111
DKHVP
2116
GSPFT
2121
VKVTG
2126
EGRMK
2131
ESITR
2136
RRQAP
2141
SIATI
2146
GSTCD
2151
LNLKI
2156
PGNWF
2161
QMVSA
2166
QERLT
2171
RTFTR
2176
SSHTY
2181
TRTER
2186
TEISK
2191
TRGGE
2196
TKREV
2201
RVEES
2206
TQVGG
2211
DPFPA
2216
VFGDF
2221
LGRER
2226
LGSFG
2231
SITRQ
2236
QEGEA
2241
SSQDM
2246
TAQVT
2251
SPSGK
2256
VEAAE
2261
IVEGE
2266
DSAYS
2271
VRFVP
2276
QEMGP
2281
HTVAV
2286
KYRGQ
2291
HVPGS
2296
PFQFT
2301
VGPLG
2306
EGGAH
2311
KVRAG
2316
GTGLE
2321
RGVAG
2326
VPAEF
2331
SIWTR
2336
EAGAG
2341
GLSIA
2346
VEGPS
2351
KAEIA
2356
FEDRK
2361
DGSCG
2366
VSYVV
2371
QEPGD
2376
YEVSI
2381
KFNDE
2386
HIPDS
2391
PFVVP
2396
VASLS
2401
DDARR
2406
LTVTS
2411
LQETG
2416
LKVNQ
2421
PASFA
2426
VQLNG
2431
ARGVI
2436
DARVH
2441
TPSGA
2446
VEECY
2451
VSELD
2456
SDKHT
2461
IRFIP
2466
HENGV
2471
HSIDV
2476
KFNGA
2481
HIPGS
2486
PFKIR
2491
VGEQS
2496
QAGDP
2501
GLVSA
2506
YGPGL
2511
EGGTT
2516
GVSSE
2521
FIVNT
2526
LNAGS
2531
GALSV
2536
TIDGP
2541
SKVQL
2546
DCREC
2551
PEGHV
2556
VTYTP
2561
MAPGN
2566
YLIAI
2571
KYGGP
2576
QHIVG
2581
SPFKA
2586
KVTGP
2591
RLSGG
2596
HSLHE
2601
TSTVL
2606
VETVT
2611
KSSSS
2616
RGSSY
2621
SSIPK
2626
FSSDA
2631
SKVVT
2636
RGPGL
2641
SQAFV
2646
GQKNS
2651
FTVDC
2656
SKAGT
2661
NMMMV
2666
GVHGP
2671
KTPCE
2676
EVYVK
2681
HMGNR
2686
VYNVT
2691
YTVKE
2696
KGDYI
2701
LIVKW
2706
GDESV
2711
PGSPF
2716
KVKVP
2721
Mutation Information
DNA mutation:
None
Peptide Range:
2583 ~ 2607
Mut AA position:
2595 (13 in Wild Type peptide)
Alignment
Wild Type:
"IVGSPFKAKVTGPRLSGGHSLHETS
||||||||||||.||||||||||||
Mutant:
IVGSPFKAKVTGSRLSGGHSLHETS"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay