Immunogenicity 14174
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
TTLL5
Transcript ID
NM_015072
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1281 aa)
MPIVM
1
ARDLE
6
ETASS
11
SEDEE
16
VISQE
21
DHPCI
26
MWTGG
31
CRRIP
36
VLVFH
41
ADAIL
46
TKDNN
51
IRVIG
56
ERYHL
61
SYKIV
66
RTDSR
71
LVRSI
76
LTAHG
81
FHEVH
86
PSSTD
91
YNLMW
96
TGSHL
101
KPFLL
106
RTLSE
111
AQKVN
116
HFPRS
121
YELTR
126
KDRLY
131
KNIIR
136
MQHTH
141
GFKAF
146
HILPQ
151
TFLLP
156
AEYAE
161
FCNSY
166
SKDRG
171
PWIVK
176
PVASS
181
RGRGV
186
YLINN
191
PNQIS
196
LEENI
201
LVSRY
206
INNPL
211
LIDDF
216
KFDVR
221
LYVLV
226
TSYDP
231
LVIYL
236
YEEGL
241
ARFAT
246
VRYDQ
251
GAKNI
256
RNQFM
261
HLTNY
266
SVNKK
271
SGDYV
276
SCDDP
281
EVEDY
286
GNKWS
291
MSAML
296
RYLKQ
301
EGRDT
306
TALMA
311
HVEDL
316
IIKTI
321
ISAEL
326
AIATA
331
CKTFV
336
PHRSS
341
CFELY
346
GFDVL
351
IDSTL
356
KPWLL
361
EVNLS
366
PSLAC
371
DAPLD
376
LKIKA
381
SMISD
386
MFTVV
391
GFVCQ
396
DPAQR
401
ASTRP
406
IYPTF
411
ESSRR
416
NPFQK
421
PQRCR
426
PLSAS
431
DAEMK
436
NLVGS
441
AREKG
446
PGKLG
451
GSVLG
456
LSMEE
461
IKVLR
466
RVKEE
471
NDRRG
476
GFIRI
481
FPTSE
486
TWEIY
491
GSYLE
496
HKTSM
501
NYMLA
506
TRLFQ
511
DRMTA
516
DGAPE
521
LKIES
526
LNSKA
531
KLHAA
536
LYERK
541
LLSLE
546
VRKRR
551
RRSSR
556
LRAMR
561
PKYPV
566
ITQPA
571
EMNVK
576
TETES
581
EEEEE
586
VALDN
591
EDEEQ
596
EASQE
601
ESAGF
606
LRENQ
611
AKYTP
616
SLTAL
621
VENTP
626
KENSM
631
KVREW
636
NNKGG
641
HCCKL
646
ETQEL
651
EPKFN
656
LMQIL
661
QDNGN
666
LSKMQ
671
ARIAF
676
SAYLQ
681
HVQIR
686
LMKDS
691
GGQTF
696
SASWA
701
AKEDE
706
QMELV
711
VRFLK
716
RASNN
721
LQHSL
726
RMVLP
731
SRRLA
736
LLERR
741
RILAH
746
QLGDF
751
IIVYN
756
KETEQ
761
MAEKK
766
SKKKV
771
EEEEE
776
DGVNM
781
ENFQE
786
FIRQA
791
SEAEL
796
EEVLT
801
FYTQK
806
NKSAS
811
VFLGT
816
HSKIS
821
KNNNN
826
YSDSG
831
AKGDH
836
PETIM
841
EEVKI
846
KPPKQ
851
QQTTE
856
IHSDK
861
LSRFT
866
TSAEK
871
EAKLV
876
YSNSS
881
SGPTA
886
TLQKI
891
PNTHL
896
SSVTT
901
SDLSP
906
GPCHH
911
SSLSQ
916
IPSAI
921
PSMPH
926
QPTIL
931
LNTVS
936
ASASP
941
CLHPG
946
AQNIP
951
SPTGL
956
PRCRS
961
GSHTI
966
GPFSS
971
FQSAA
976
HIYSQ
981
KLSRP
986
SSAKA
991
GSCYL
996
NKHHS
1001
GIAKT
1006
QKEGE
1011
DASLY
1016
SKRYN
1021
QSMVT
1026
AELQR
1031
LAEKQ
1036
AARQY
1041
SPSSH
1046
INLLT
1051
QQVTN
1056
LNLAT
1061
GIINR
1066
SSASA
1071
PPTLR
1076
PIISP
1081
SGPTW
1086
STQSD
1091
PQAPE
1096
NHSSS
1101
PGSRS
1106
LQTGG
1111
FAWEG
1116
EVENN
1121
VYSQA
1126
TGVVP
1131
QHKYH
1136
PTAGS
1141
YQLQF
1146
ALQQL
1151
EQQKL
1156
QSRQL
1161
LDQSR
1166
ARHQA
1171
IFGSQ
1176
TLPNS
1181
NLWTM
1186
NNGAG
1191
CRISS
1196
ATASG
1201
QKPTT
1206
LPQKV
1211
VPPPS
1216
SCASL
1221
VPKPP
1226
PNHEQ
1231
VLRRA
1236
TSQKA
1241
SKGSS
1246
AEGQL
1251
NGLQS
1256
SLNPA
1261
AFVPI
1266
TSSTD
1271
PAHTK
1276
I
1281
Mutation Information
DNA mutation:
None
Peptide Range:
267 ~ 291
Mut AA position:
279 (13 in Wild Type peptide)
Alignment
Wild Type:
"LTNYSVNKKSGDYVSCDDPEVEDYG
||||||||||||.||||||||||||
Mutant:
LTNYSVNKKSGDFVSCDDPEVEDYG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) TTLL5
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay