Immunogenicity 14175
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SLIT2
Transcript ID
NM_004787
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (1529 aa)
MRGVG
1
WQMLS
6
LSLGL
11
VLAIL
16
NKVAP
21
QACPA
26
QCSCS
31
GSTVD
36
CHGLA
41
LRSVP
46
RNIPR
51
NTERL
56
DLNGN
61
NITRI
66
TKTDF
71
AGLRH
76
LRVLQ
81
LMENK
86
ISTIE
91
RGAFQ
96
DLKEL
101
ERLRL
106
NRNHL
111
QLFPE
116
LLFLG
121
TAKLY
126
RLDLS
131
ENQIQ
136
AIPRK
141
AFRGA
146
VDIKN
151
LQLDY
156
NQISC
161
IEDGA
166
FRALR
171
DLEVL
176
TLNNN
181
NITRL
186
SVASF
191
NHMPK
196
LRTFR
201
LHSNN
206
LYCDC
211
HLAWL
216
SDWLR
221
QRPRV
226
GLYTQ
231
CMGPS
236
HLRGH
241
NVAEV
246
QKREF
251
VCSGH
256
QSFMA
261
PSCSV
266
LHCPA
271
ACTCS
276
NNIVD
281
CRGKG
286
LTEIP
291
TNLPE
296
TITEI
301
RLEQN
306
TIKVI
311
PPGAF
316
SPYKK
321
LRRID
326
LSNNQ
331
ISELA
336
PDAFQ
341
GLRSL
346
NSLVL
351
YGNKI
356
TELPK
361
SLFEG
366
LFSLQ
371
LLLLN
376
ANKIN
381
CLRVD
386
AFQDL
391
HNLNL
396
LSLYD
401
NKLQT
406
IAKGT
411
FSPLR
416
AIQTM
421
HLAQN
426
PFICD
431
CHLKW
436
LADYL
441
HTNPI
446
ETSGA
451
RCTSP
456
RRLAN
461
KRIGQ
466
IKSKK
471
FRCSA
476
KEQYF
481
IPGTE
486
DYRSK
491
LSGDC
496
FADLA
501
CPEKC
506
RCEGT
511
TVDCS
516
NQKLN
521
KIPEH
526
IPQYT
531
AELRL
536
NNNEF
541
TVLEA
546
TGIFK
551
KLPQL
556
RKINF
561
SNNKI
566
TDIEE
571
GAFEG
576
ASGVN
581
EILLT
586
SNRLE
591
NVQHK
596
MFKGL
601
ESLKT
606
LMLRS
611
NRITC
616
VGNDS
621
FIGLS
626
SVRLL
631
SLYDN
636
QITTV
641
APGAF
646
DTLHS
651
LSTLN
656
LLANP
661
FNCNC
666
YLAWL
671
GEWLR
676
KKRIV
681
TGNPR
686
CQKPY
691
FLKEI
696
PIQDV
701
AIQDF
706
TCDDG
711
NDDNS
716
CSPLS
721
RCPTE
726
CTCLD
731
TVVRC
736
SNKGL
741
KVLPK
746
GIPRD
751
VTELY
756
LDGNQ
761
FTLVP
766
KELSN
771
YKHLT
776
LIDLS
781
NNRIS
786
TLSNQ
791
SFSNM
796
TQLLT
801
LILSY
806
NRLRC
811
IPPRT
816
FDGLK
821
SLRLL
826
SLHGN
831
DISVV
836
PEGAF
841
NDLSA
846
LSHLA
851
IGANP
856
LYCDC
861
NMQWL
866
SDWVK
871
SEYKE
876
PGIAR
881
CAGPG
886
EMADK
891
LLLTT
896
PSKKF
901
TCQGP
906
VDVNI
911
LAKCN
916
PCLSN
921
PCKND
926
GTCNS
931
DPVDF
936
YRCTC
941
PYGFK
946
GQDCD
951
VPIHA
956
CISNP
961
CKHGG
966
TCHLK
971
EGEED
976
GFWCI
981
CADGF
986
EGENC
991
EVNVD
996
DCEDN
1001
DCENN
1006
STCVD
1011
GINNY
1016
TCLCP
1021
PEYTG
1026
ELCEE
1031
KLDFC
1036
AQDLN
1041
PCQHD
1046
SKCIL
1051
TPKGF
1056
KCDCT
1061
PGYVG
1066
EHCDI
1071
DFDDC
1076
QDNKC
1081
KNGAH
1086
CTDAV
1091
NGYTC
1096
ICPEG
1101
YSGLF
1106
CEFSP
1111
PMVLP
1116
RTSPC
1121
DNFDC
1126
QNGAQ
1131
CIVRI
1136
NEPIC
1141
QCLPG
1146
YQGEK
1151
CEKLV
1156
SVNFI
1161
NKESY
1166
LQIPS
1171
AKVRP
1176
QTNIT
1181
LQIAT
1186
DEDSG
1191
ILLYK
1196
GDKDH
1201
IAVEL
1206
YRGRV
1211
RASYD
1216
TGSHP
1221
ASAIY
1226
SVETI
1231
NDGNF
1236
HIVEL
1241
LALDQ
1246
SLSLS
1251
VDGGN
1256
PKIIT
1261
NLSKQ
1266
STLNF
1271
DSPLY
1276
VGGMP
1281
GKSNV
1286
ASLRQ
1291
APGQN
1296
GTSFH
1301
GCIRN
1306
LYINS
1311
ELQDF
1316
QKVPM
1321
QTGIL
1326
PGCEP
1331
CHKKV
1336
CAHGT
1341
CQPSS
1346
QAGFT
1351
CECQE
1356
GWMGP
1361
LCDQR
1366
TNDPC
1371
LGNKC
1376
VHGTC
1381
LPINA
1386
FSYSC
1391
KCLEG
1396
HGGVL
1401
CDEEE
1406
DLFNP
1411
CQAIK
1416
CKHGK
1421
CRLSG
1426
LGQPY
1431
CECSS
1436
GYTGD
1441
SCDRE
1446
ISCRG
1451
ERIRD
1456
YYQKQ
1461
QGYAA
1466
CQTTK
1471
KVSRL
1476
ECRGG
1481
CAGGQ
1486
CCGPL
1491
RSKRR
1496
KYSFE
1501
CTDGS
1506
SFVDE
1511
VEKVV
1516
KCGCT
1521
RCVS
1526
Mutation Information
DNA mutation:
None
Peptide Range:
703 ~ 727
Mut AA position:
715 (13 in Wild Type peptide)
Alignment
Wild Type:
"QDVAIQDFTCDDGNDDNSCSPLSRC
||||||||||||.||||||||||||
Mutant:
QDVAIQDFTCDDENDDNSCSPLSRC"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) SLIT2
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay