Immunogenicity 14190

summary
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
EPB41L2
Transcript ID
NM_001135554
HLA INFO
C*02:02
TCR INFO

No TCR info found!

T cell Tumor cell C*02:02
sequence
Full length protein sequence (673 aa)
MTTEV
1
GSVSE
6
VKKDS
11
SQLGT
16
DATKE
21
KPKEV
26
AENQQ
31
NQSSD
36
PEEEK
41
GSQPP
46
PAAES
51
QSSLR
56
RQKRE
61
KETSE
66
SRGIS
71
RFIPP
76
WLKKQ
81
KSYTL
86
VVAKD
91
GGDKK
96
EPTQA
101
VVEEQ
106
VLDKE
111
EPLPE
116
EQRQA
121
KGDAE
126
EMAQK
131
KQEIK
136
VEVKE
141
EKPSV
146
SKEEK
151
PSVSK
156
VEMQP
161
TELVS
166
KEREE
171
KVKET
176
QEDKL
181
EGGAA
186
KRETK
191
EVQTN
196
ELKAE
201
KASQK
206
VTKKT
211
KTVQC
216
KVTLL
221
DGTEY
226
SCDLE
231
KHAKG
236
QVLFD
241
KVCEH
246
LNLLE
251
KDYFG
256
LLFQE
261
SPEQK
266
NWLDP
271
AKEIK
276
RQLRN
281
LPWLF
286
TFNVK
291
FYPPD
296
PSQLT
301
EDITR
306
YFLCL
311
QLRQD
316
IASGR
321
LPCSF
326
VTHAL
331
LGSYT
336
LQAEL
341
GDYDP
346
EEHGS
351
IDLSE
356
FQFAP
361
TQTKE
366
LEEKV
371
AELHK
376
THRGL
381
SPAQA
386
DSQFL
391
ENAKR
396
LSMYG
401
VDLHH
406
AKDSE
411
GVDIK
416
LGVCA
421
NGLLI
426
YKDRL
431
RINRF
436
AWPKI
441
LKISY
446
KRSNF
451
YIKVR
456
PAELE
461
QFEST
466
IGFKL
471
PNHRA
476
AKRLW
481
KVCVE
486
HHTFY
491
RLVSP
496
EQPPK
501
AKFLT
506
LGSKF
511
RYSGR
516
TQAQT
521
RQAST
526
LIDRP
531
APHFE
536
RTSSK
541
RVSRS
546
LDGAP
551
IGVMD
556
QSLMK
561
DFPGA
566
AGEIS
571
AYGPG
576
LVSIA
581
VVQDG
586
DGRRE
591
VRSPT
596
KAPHL
601
QLIEG
606
KTVKG
611
GISET
616
RIEKR
621
IVITG
626
DGDID
631
HDQAL
636
AQAIR
641
EAREQ
646
HPDMS
651
VTRVV
656
VHKET
661
ELAEE
666
GED
671
Mutation Information
DNA mutation:
None
Peptide Range:
504 ~ 528
Mut AA position:
516 (13 in Wild Type peptide)
Alignment
Wild Type:
"PKAKFLTLGSKFRYSGRTQAQTRQA
||||||||||||.||||||||||||
Mutant:
PKAKFLTLGSKFCYSGRTQAQTRQA"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay