Immunogenicity 142
Sample ID
4196
Response
Negative
Tumor Type
Colorectal cancer
Gene Symbol
FAM135B
Transcript ID
uc003yuy.3
HLA INFO
A*24:01
TCR INFO
No TCR info found!
Full length protein sequence (1410 aa)
MSEIQ
1
GTVEF
6
SVELH
11
KFYNV
16
DLFQR
21
GYYQI
26
RVTLK
31
VSSRI
36
PHRLS
41
ASIAG
46
QTESS
51
SLHSA
56
CVHDS
61
TVHSR
66
VFQIL
71
YRNEE
76
VPIND
81
AVVFR
86
VHLLL
91
GGERM
96
EDALS
101
EVDFQ
106
LKVDL
111
HFTDS
116
EQQLR
121
DVAGA
126
PMVSS
131
RTLGL
136
HFHPR
141
NGLHH
146
QVPVM
151
FDYFH
156
LSVIS
161
VTVHA
166
ALVAL
171
QQPLI
176
SFTRP
181
GRGSW
186
LGKGG
191
PDTGQ
196
EQSII
201
SLENL
206
VFGAG
211
YCKPT
216
SSEGS
221
FYITS
226
ENCMQ
231
HAHKW
236
HRDLC
241
LLLLH
246
AYRGL
251
RLHFL
256
VIMRD
261
IPELP
266
HTELE
271
ALAVE
276
ETLSQ
281
LCSEL
286
QMLNN
291
PEKIA
296
EQISK
301
DLAWL
306
TSHMM
311
TLWTQ
316
FLDTV
321
TLHSQ
326
VTTYL
331
TQEHH
336
TLRVR
341
RFSEA
346
FFYME
351
HQKLA
356
VLTFQ
361
ENLIQ
366
THSQL
371
SLDIR
376
NSEYL
381
TSMPP
386
LPAEC
391
LDIDG
396
DWNTL
401
PVIFE
406
DRYVD
411
CPATG
416
HNLSV
421
YPNFD
426
VPVTS
431
PTIMN
436
LKDKE
441
DNCMV
446
NSNLS
451
FREDL
456
VLSTI
461
KPSQM
466
DSDEE
471
VIRCP
476
EPGEN
481
VATQN
486
HMDMC
491
SESQV
496
YISIG
501
EFQNK
506
AGVPE
511
DECWT
516
GQTSD
521
AGTYP
526
VADVD
531
TSRRS
536
PGPED
541
GQAPV
546
LTYID
551
VKSSN
556
KNPSR
561
AEPLV
566
AFNAQ
571
HESRS
576
SRDKY
581
GLDRT
586
GLSKV
591
VVGGS
596
HQNAI
601
SSDKT
606
TLHEL
611
STLGK
616
GIDQE
621
GKMVL
626
LSLKL
631
TPSEP
636
CDPLS
641
STLRE
646
PLDIR
651
SSLKD
656
SHTEE
661
QEELS
666
VLSGV
671
IKRSS
676
SIISD
681
SGIES
686
EPSSV
691
AWSEA
696
RSRAL
701
ELPSD
706
REVLH
711
PFVRR
716
HALHR
721
NSLEG
726
GHTES
731
NTSLP
736
SGIQA
741
SLTSI
746
SSLPF
751
EEDER
756
EVALT
761
KLTKS
766
VSAPH
771
ISSPE
776
EAAED
781
ADTKQ
786
QDGGF
791
AEPSD
796
MHSKS
801
QGSPG
806
SCSQL
811
CGDSG
816
TDAGA
821
DHPLV
826
EIVLD
831
ADNQQ
836
GPGYI
841
DIPKG
846
KGKQF
851
DAQGH
856
CLPDG
861
RTENT
866
PGVET
871
KGLNL
876
KIPRV
881
IALEN
886
PRTRS
891
LHRAL
896
EETPK
901
GMPKD
906
LNVGQ
911
QALSN
916
SGISE
921
VEGLS
926
QHQVP
931
ELSCT
936
SAADA
941
INRNS
946
TGQQS
951
QSGSP
956
CIMDD
961
TAFNR
966
GVNAF
971
PEAKH
976
KAGTV
981
CPTVT
986
HSVHS
991
QVLKN
996
QELKA
1001
GTSIM
1006
GSHLT
1011
SAETF
1016
TLDSL
1021
KAVEV
1026
VNLSV
1031
SCTAT
1036
CLPFS
1041
SVPKE
1046
TPARA
1051
GFSSK
1056
QTLFP
1061
ITHQP
1066
LGSFG
1071
VVSTH
1076
SSTLD
1081
EEVSE
1086
RMFSV
1091
FSSFY
1096
QAKEK
1101
FKKEL
1106
KIEGF
1111
LYSDL
1116
TVLAS
1121
DIPYF
1126
PPEEE
1131
EENLE
1136
DGIHL
1141
VVCVH
1146
GLDGN
1151
SADLR
1156
LVKTF
1161
IELGL
1166
PGGKL
1171
DFLMS
1176
EKNQM
1181
DTFAD
1186
FDTMT
1191
DRLLD
1196
EIIQH
1201
IQLYN
1206
LSISR
1211
ISFIG
1216
HSLGN
1221
IIIRS
1226
VLTRP
1231
RFRYY
1236
LNKLH
1241
TFLSL
1246
SGPHL
1251
GTLYN
1256
NSTLV
1261
STGLW
1266
LMQKL
1271
KKSGS
1276
LLQLT
1281
FRDNA
1286
DLRKC
1291
FLYQL
1296
SQKTG
1301
LQYFK
1306
NVVLV
1311
ASPQD
1316
RYVPF
1321
HSARI
1326
EMCKT
1331
ALKDR
1336
HTGPV
1341
YAEMI
1346
NNLLG
1351
PLVEA
1356
KDCTL
1361
IRHNV
1366
FHALP
1371
NTANT
1376
LIGRA
1381
AHIAV
1386
LDSEL
1391
FLEKF
1396
FLVAG
1401
LNYFK
1406
Mutation Information
DNA mutation:
c.C1310A
Peptide Range:
425 ~ 449
Mut AA position:
437 (13 in Wild Type peptide)
Alignment
Wild Type:
"VYPNFDVPVTSPTIMNLKDKEDNCM
||||||||||||.||||||||||||
Mutant:
VYPNFDVPVTSPKIMNLKDKEDNCM"
Cancer Immunol Res, 2019
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal CancerGene Name (from Reference) FAM135B
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
VYPNFDVPVTSPKIMNLKDKEDNCM
Antigen
Type
TMG
T-cell
Source
TILs
APC
Type
DSs
Assay
ELISPOT