Immunogenicity 14240
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DHX38
Transcript ID
NM_014003
HLA INFO
A*24:02
TCR INFO
No TCR info found!
Full length protein sequence (1227 aa)
MGDTS
1
EDASI
6
HRLEG
11
TDLDC
16
QVGGL
21
ICKSK
26
SAASE
31
QHVFK
36
APAPR
41
PSLLG
46
LDLLA
51
SLKRR
56
EREEK
61
DDGED
66
KKKSK
71
VSSYK
76
DWEES
81
KDDQK
86
DAEEE
91
GGDQA
96
GQNIR
101
KDRHY
106
RSARV
111
ETPSH
116
PGGVS
121
EEFWE
126
RSRQR
131
ERERR
136
EHGVY
141
ASSKE
146
EKDWK
151
KEKSR
156
DRDYD
161
RKRDR
166
DERDR
171
SRHSS
176
RSERD
181
GGSER
186
SSRRN
191
EPESP
196
RHRPK
201
DAATP
206
SRSTW
211
EEEDS
216
GYGSS
221
RRSQW
226
ESPSP
231
TPSYR
236
DSERS
241
HRLST
246
RDRDR
251
SVRGK
256
YSDDT
261
PLPTP
266
SYKYN
271
EWADD
276
RRHLG
281
STPRL
286
SRGRG
291
RREEG
296
EEGIS
301
FDTEE
306
ERQQW
311
EDDQR
316
QADRD
321
WYMMD
326
EGYDE
331
FHNPL
336
AYSSE
341
DYVRR
346
REQHL
351
HKQKQ
356
KRISA
361
QRRQI
366
NEDNE
371
RWETN
376
RMLTS
381
GVVHR
386
LEVDE
391
DFEED
396
NAAKV
401
HLMVH
406
NLVPP
411
FLDGR
416
IVFTK
421
QPEPV
426
IPVKD
431
ATSDL
436
AIIAR
441
KGSQT
446
VRKHR
451
EQKER
456
KKAQH
461
KHWEL
466
AGTKL
471
GDIMG
476
VKKEE
481
EPDKA
486
VTEDG
491
KVDYR
496
TEQKF
501
ADHMK
506
RKSEA
511
SSEFA
516
KKKSI
521
LEQRQ
526
YLPIF
531
AVQQE
536
LLTII
541
RDNSI
546
VIVVG
551
ETGSG
556
KTTQL
561
TQYLH
566
EDGYT
571
DYGMI
576
GCTQP
581
RRVAA
586
MSVAK
591
RVSEE
596
MGGNL
601
GEEVG
606
YAIRF
611
EDCTS
616
ENTLI
621
KYMTD
626
GILLR
631
ESLRE
636
ADLDH
641
YSAII
646
MDEAH
651
ERSLN
656
TDVLF
661
GLLRE
666
VVARR
671
SDLKL
676
IVTSA
681
TMDAE
686
KFAAF
691
FGNVP
696
IFHIP
701
GRTFP
706
VDILF
711
SKTPQ
716
EDYVE
721
AAVKQ
726
SLQVH
731
LSGAP
736
GDILI
741
FMPGQ
746
EDIEV
751
TSDQI
756
VEHLE
761
ELENA
766
PALAV
771
LPIYS
776
QLPSD
781
LQAKI
786
FQKAP
791
DGVRK
796
CIVAT
801
NIAET
806
SLTVD
811
GIMFV
816
IDSGY
821
CKLKV
826
FNPRI
831
GMDAL
836
QIYPI
841
SQANA
846
NQRSG
851
RAGRT
856
GPGQC
861
FRLYT
866
QSAYK
871
NELLT
876
TTVPE
881
IQRTN
886
LANVV
891
LLLKS
896
LGVQD
901
LLQFH
906
FMDPP
911
PEDNM
916
LNSMY
921
QLWIL
926
GALDN
931
TGGLT
936
STGRL
941
MVEFP
946
LDPAL
951
SKMLI
956
VSCDM
961
GCSSE
966
ILLIV
971
SMLSV
976
PAIFY
981
RPKGR
986
EEESD
991
QIREK
996
FAVPE
1001
SDHLT
1006
YLNVY
1011
LQWKN
1016
NNYST
1021
IWCND
1026
HFIHA
1031
KAMRK
1036
VREVR
1041
AQLKD
1046
IMVQQ
1051
RMSLA
1056
SCGTD
1061
WDIVR
1066
KCICA
1071
AYFHQ
1076
AAKLK
1081
GIGEY
1086
VNIRT
1091
GMPCH
1096
LHPTS
1101
SLFGM
1106
GYTPD
1111
YIVYH
1116
ELVMT
1121
TKEYM
1126
QCVTA
1131
VDGEW
1136
LAELG
1141
PMFYS
1146
VKQAG
1151
KSRQE
1156
NRRRA
1161
KEEAS
1166
AMEEE
1171
MALAE
1176
EQLRA
1181
RRQEQ
1186
EKRSP
1191
LGSVR
1196
STKIY
1201
TPGRK
1206
EQGEP
1211
MTPRR
1216
TPARF
1221
GL
1226
Mutation Information
DNA mutation:
None
Peptide Range:
293 ~ 317
Mut AA position:
305 (13 in Wild Type peptide)
Alignment
Wild Type:
"GRGRREEGEEGISFDTEEERQQWED
||||||||||||.||||||||||||
Mutant:
GRGRREEGEEGILFDTEEERQQWED"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DHX38
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay