Immunogenicity 14270
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DHX16
Transcript ID
NM_003587
HLA INFO
B*07:01
TCR INFO
No TCR info found!
Full length protein sequence (1041 aa)
MATPA
1
GLERW
6
VQDEL
11
HSVLG
16
LSERH
21
VAQFL
26
IGTAQ
31
RCTSA
36
EEFVQ
41
RLRDT
46
DTLDL
51
SGPAR
56
DFALR
61
LWNKV
66
PRKAV
71
VEKPA
76
RAAER
81
EARAL
86
LEKNR
91
SYRLL
96
EDSEE
101
SSEET
106
VSRAG
111
SSLQK
116
KRKKR
121
KHLRK
126
KREEE
131
EEEEA
136
SEKGK
141
KKTGG
146
SKQQT
151
EKPES
156
EDEWE
161
RTERE
166
RLQDL
171
EERDA
176
FAERV
181
RQRDK
186
DRTRN
191
VLERS
196
DKKAY
201
EEAQK
206
RLKMA
211
EEDRK
216
AMVPE
221
LRKKS
226
RREYL
231
AKRER
236
EKLED
241
LEAEL
246
ADEEF
251
LFGDV
256
ELSRH
261
ERQEL
266
KYKRR
271
VRDLA
276
REYRA
281
AGEQE
286
KLEAT
291
NRYHM
296
PKETR
301
GQPAR
306
AVDLV
311
EEESG
316
APGEE
321
QRRWE
326
EARLG
331
AASLK
336
FGARD
341
AASQE
346
PKYQL
351
VLEEE
356
ETIEF
361
VRATQ
366
LQGDE
371
EPSAP
376
PTSTQ
381
AQQKE
386
SIQAV
391
RRSLP
396
VFPFR
401
EELLA
406
AIANH
411
QVLII
416
EGETG
421
SGKTT
426
QIPQY
431
LFEEG
436
YTNKG
441
MKIAC
446
TQPRR
451
VAAMS
456
VAARV
461
AREMG
466
VKLGN
471
EVGYS
476
IRFED
481
CTSER
486
TVLRY
491
MTDGM
496
LLREF
501
LSEPD
506
LASYS
511
VVMVD
516
EAHER
521
TLHTD
526
ILFGL
531
IKDVA
536
RFRPE
541
LKVLV
546
ASATM
551
DTARF
556
STFFD
561
DAPVF
566
RIPGR
571
RFPVD
576
IFYTK
581
APEAD
586
YLEAC
591
VVSVL
596
QIHVT
601
QPPGD
606
ILVFL
611
TGQEE
616
IEAAC
621
EMLQD
626
RCRRL
631
GSKIR
636
ELLVL
641
PIYAN
646
LPSDM
651
QARIF
656
QPTPP
661
GARKV
666
VVATN
671
IAETS
676
LTIEG
681
IIYVL
686
DPGFC
691
KQKSY
696
NPRTG
701
MESLT
706
VTPCS
711
KASAN
716
QRAGR
721
AGRVA
726
AGKCF
731
RLYTA
736
WAYQH
741
ELEET
746
TVPEI
751
QRTSL
756
GNVVL
761
LLKSL
766
GIHDL
771
MHFDF
776
LDPPP
781
YETLL
786
LALEQ
791
LYALG
796
ALNHL
801
GELTT
806
SGRKM
811
AELPV
816
DPMLS
821
KMILA
826
SEKYS
831
CSEEI
836
LTVAA
841
MLSVN
846
NSIFY
851
RPKDK
856
VVHAD
861
NARVN
866
FFLPG
871
GDHLV
876
LLNVY
881
TQWAE
886
SGYSS
891
QWCYE
896
NFVQF
901
RSMRR
906
ARDVR
911
EQLEG
916
LLERV
921
EVGLS
926
SCQGD
931
YIRVR
936
KAITA
941
GYFYH
946
TARLT
951
RSGYR
956
TVKQQ
961
QTVFI
966
HPNSS
971
LFEQQ
976
PRWLL
981
YHELV
986
LTTKE
991
FMRQV
996
LEIES
1001
SWLLE
1006
VAPHY
1011
YKAKE
1016
LEDPH
1021
AKKMP
1026
KKIGK
1031
TREEL
1036
G
1041
Mutation Information
DNA mutation:
None
Peptide Range:
561 ~ 585
Mut AA position:
573 (13 in Wild Type peptide)
Alignment
Wild Type:
"STFFDDAPVFRIPGRRFPVDIFYTK
||||||||||||.||||||||||||
Mutant:
STFFDDAPVFRISGRRFPVDIFYTK"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DHX16
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay