Immunogenicity 14316

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ITPR3
Transcript ID
NM_002224
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (2671 aa)
MSEMS
1
SFLHI
6
GDIVS
11
LYAEG
16
SVNGF
21
ISTLG
26
LVDDR
31
CVVEP
36
AAGDL
41
DNPPK
46
KFRDC
51
LFKVC
56
PMNRY
61
SAQKQ
66
YWKAK
71
QTKQD
76
KEKIA
81
DVVLL
86
QKLQH
91
AAQME
96
QKQND
101
TENKK
106
VHGDV
111
VKYGS
116
VIQLL
121
HMKSN
126
KYLTV
131
NKRLP
136
ALLEK
141
NAMRV
146
TLDAT
151
GNEGS
156
WLFIQ
161
PFWKL
166
RSNGD
171
NVVVG
176
DKVIL
181
NPVNA
186
GQPLH
191
ASNYE
196
LSDNA
201
GCKEV
206
NSVNC
211
NTSWK
216
INLFM
221
QFRDH
226
LEEVL
231
KGGDV
236
VRLFH
241
AEQEK
246
FLTCD
251
EYKGK
256
LQVFL
261
RTTLR
266
QSATS
271
ATSSN
276
ALWEV
281
EVVHH
286
DPCRG
291
GAGHW
296
NGLYR
301
FKHLA
306
TGNYL
311
AAEEN
316
PSYKG
321
DASDP
326
KAAGM
331
GAQGR
336
TGRRN
341
AGEKI
346
KYCLV
351
AVPHG
356
NDIAS
361
LFELD
366
PTTLQ
371
KTDSF
376
VPRNS
381
YVRLR
386
HLCTN
391
TWIQS
396
TNVPI
401
DIEEE
406
RPIRL
411
MLGTC
416
PTKED
421
KEAFA
426
IVSVP
431
VSEIR
436
DLDFA
441
NDASS
446
MLASA
451
VEKLN
456
EGFIS
461
QNDRR
466
FVIQL
471
LEDLV
476
FFVSD
481
VPNNG
486
QNVLD
491
IMVTK
496
PNRER
501
QKLMR
506
EQNIL
511
KQVFG
516
ILKAP
521
FREKG
526
GEGPL
531
VRLEE
536
LSDQK
541
NAPYQ
546
HMFRL
551
CYRVL
556
RHSQE
561
DYRKN
566
QEHIA
571
KQFGM
576
MQSQI
581
GYDIL
586
AEDTI
591
TALLH
596
NNRKL
601
LEKHI
606
TKTEV
611
ETFVS
616
LVRKN
621
REPRF
626
LDYLS
631
DLCVS
636
NHIAI
641
PVTQE
646
LICKC
651
VLDPK
656
NSDIL
661
IRTEL
666
RPVKE
671
MAQSH
676
EYLSI
681
EYSEE
686
EVWLT
691
WTDKN
696
NEHHE
701
KSVRQ
706
LAQEA
711
RAGNA
716
HDENV
721
LSYYR
726
YQLKL
731
FARMC
736
LDRQY
741
LAIDE
746
ISQQL
751
GVDLI
756
FLCMA
761
DEMLP
766
FDLRA
771
SFCHL
776
MLHVH
781
VDRDP
786
QELVT
791
PVKFA
796
RLWTE
801
IPTAI
806
TIKDY
811
DSNLN
816
ASRDD
821
KKNKF
826
ANTME
831
FVEDY
836
LNNVV
841
SEAVP
846
FANEE
851
KNKLT
856
FEVVS
861
LAHNL
866
IYFGF
871
YSFSE
876
LLRLT
881
RTLLG
886
IIDCV
891
QGPPA
896
MLQAY
901
EDPGG
906
KNVRR
911
SIQGV
916
GHMMS
921
TMVLS
926
RKQSV
931
FSAPS
936
LSAGA
941
SAAEP
946
LDRSK
951
FEENE
956
DIVVM
961
ETKLK
966
ILEIL
971
QFILN
976
VRLDY
981
RISYL
986
LSVFK
991
KEFVE
996
VFPMQ
1001
DSGAD
1006
GTAPA
1011
FDSTT
1016
ANMNL
1021
DRIGE
1026
QAEAM
1031
FGVGK
1036
TSSML
1041
EVDDE
1046
GGRMF
1051
LRVLI
1056
HLTMH
1061
DYAPL
1066
VSGAL
1071
QLLFK
1076
HFSQR
1081
QEAMH
1086
TFKQV
1091
QLLIS
1096
AQDVE
1101
NYKVI
1106
KSELD
1111
RLRTM
1116
VEKSE
1121
LWVDK
1126
KGSGK
1131
GEEVE
1136
AGAAK
1141
DKKER
1146
PTDEE
1151
GFLHP
1156
PGEKS
1161
SENYQ
1166
IVKGI
1171
LERLN
1176
KMCGV
1181
GEQMR
1186
KKQQR
1191
LLKNM
1196
DAHKV
1201
MLDLL
1206
QIPYD
1211
KGDAK
1216
MMEIL
1221
RYTHQ
1226
FLQKF
1231
CAGNP
1236
GNQAL
1241
LHKHL
1246
HLFLT
1251
PGLLE
1256
AETMQ
1261
HIFLN
1266
NYQLC
1271
SEISE
1276
PVLQH
1281
FVHLL
1286
ATHGR
1291
HVQYL
1296
DFLHT
1301
VIKAE
1306
GKYVK
1311
KCQDM
1316
IMTEL
1321
TNAGD
1326
DVVVF
1331
YNDKA
1336
SLAHL
1341
LDMMK
1346
AARDG
1351
VEDHS
1356
PLMYH
1361
ISLVD
1366
LLAAC
1371
AEGKN
1376
VYTEI
1381
KCTSL
1386
LPLED
1391
VVSVV
1396
THEDC
1401
ITEVK
1406
MAYVN
1411
FVNHC
1416
YVDTE
1421
VEMKE
1426
IYTSN
1431
HIWTL
1436
FENFT
1441
LDMAR
1446
VCSKR
1451
EKRVA
1456
DPTLE
1461
KYVLS
1466
VVLDT
1471
INAFF
1476
SSPFS
1481
ENSTS
1486
LQTHQ
1491
TIVVQ
1496
LLQST
1501
TRLLE
1506
CPWLQ
1511
QQHKG
1516
SVEAC
1521
IRTLA
1526
MVAKG
1531
RAILL
1536
PMDLD
1541
AHISS
1546
MLSSG
1551
ASCAA
1556
AAQRN
1561
ASSYK
1566
ATTRA
1571
FPRVT
1576
PTANQ
1581
WDYKN
1586
IIEKL
1591
QDIIT
1596
ALEER
1601
LKPLV
1606
QAELS
1611
VLVDV
1616
LHWPE
1621
LLFLE
1626
GSEAY
1631
QRCES
1636
GGFLS
1641
KLIQH
1646
TKDLM
1651
ESEEK
1656
LCIKV
1661
LRTLQ
1666
QMLLK
1671
KTKYG
1676
DRGNQ
1681
LRKML
1686
LQNYL
1691
QNRKS
1696
TSRGD
1701
LPDPI
1706
GTGLD
1711
PDWSA
1716
IAATQ
1721
CRLDK
1726
EGATK
1731
LVCDL
1736
ITSTK
1741
NEKIF
1746
QESIG
1751
LAIHL
1756
LDGGN
1761
TEIQK
1766
SFHNL
1771
MMSDK
1776
KSERF
1781
FKVLH
1786
DRMKR
1791
AQQET
1796
KSTVA
1801
VNMND
1806
LGSQP
1811
HEDRE
1816
PVDPT
1821
TKGRV
1826
ASFSI
1831
PGSSS
1836
RYSLG
1841
PSLRR
1846
GHEVS
1851
ERVQS
1856
SEMGT
1861
SVLIM
1866
QPILR
1871
FLQLL
1876
CENHN
1881
RDLQN
1886
FLRCQ
1891
NNKTN
1896
YNLVC
1901
ETLQF
1906
LDIMC
1911
GSTTG
1916
GLGLL
1921
GLYIN
1926
EDNVG
1931
LVIQT
1936
LETLT
1941
EYCQG
1946
PCHEN
1951
QTCIV
1956
THESN
1961
GIDII
1966
TALIL
1971
NDISP
1976
LCKYR
1981
MDLVL
1986
QLKDN
1991
ASKLL
1996
LALME
2001
SRHDS
2006
ENAER
2011
ILISL
2016
RPQEL
2021
VDVIK
2026
KAYLQ
2031
EEERE
2036
NSEVS
2041
PREVG
2046
HNIYI
2051
LALQL
2056
SRHNK
2061
QLQHL
2066
LKPVK
2071
RIQEE
2076
EAEGI
2081
SSMLS
2086
LNNKQ
2091
LSQML
2096
KSSAP
2101
AQEEE
2106
EDPLA
2111
YYENH
2116
TSQIE
2121
IVRQD
2126
RSMEQ
2131
IVFPV
2136
PGICQ
2141
FLTEE
2146
TKHRL
2151
FTTTE
2156
QDEQG
2161
SKVSD
2166
FFDQS
2171
SFLHN
2176
EMEWQ
2181
RKLRS
2186
MPLIY
2191
WFSRR
2196
MTLWG
2201
SISFN
2206
LAVFI
2211
NIIIA
2216
FFYPY
2221
MEGAS
2226
TGVLD
2231
SPLIS
2236
LLFWI
2241
LICFS
2246
IAALF
2251
TKRYS
2256
IRPLI
2261
VALIL
2266
RSIYY
2271
LGIGP
2276
TLNIL
2281
GALNL
2286
TNKIV
2291
FVVSF
2296
VGNRG
2301
TFIRG
2306
YKAMV
2311
MDMEF
2316
LYHVG
2321
YILTS
2326
VLGLF
2331
AHELF
2336
YSILL
2341
FDLIY
2346
REETL
2351
FNVIK
2356
SVTRN
2361
GRSIL
2366
LTALL
2371
ALILV
2376
YLFSI
2381
VGFLF
2386
LKDDF
2391
ILEVD
2396
RLPNN
2401
HSTAS
2406
PLGMP
2411
HGAAA
2416
FVDTC
2421
SGDKM
2426
DCVSG
2431
LSVPE
2436
VLEED
2441
RELDS
2446
TERAC
2451
DTLLM
2456
CIVTV
2461
MNHGL
2466
RNGGG
2471
VGDIL
2476
RKPSK
2481
DESLF
2486
PARVV
2491
YDLLF
2496
FFIVI
2501
IIVLN
2506
LIFGV
2511
IIDTF
2516
ADLRS
2521
EKQKK
2526
EEILK
2531
TTCFI
2536
CGLER
2541
DKFDN
2546
KTVSF
2551
EEHIK
2556
LEHNM
2561
WNYLY
2566
FIVLV
2571
RVKNK
2576
TDYTG
2581
PESYV
2586
AQMIK
2591
NKNLD
2596
WFPRM
2601
RAMSL
2606
VSNEG
2611
EGEQN
2616
EIRIL
2621
QDKLN
2626
STMKL
2631
VSHLT
2636
AQLNE
2641
LKEQM
2646
TEQRK
2651
RRQRL
2656
GFVDV
2661
QNCIS
2666
R
2671
Mutation Information
DNA mutation:
None
Peptide Range:
278 ~ 302
Mut AA position:
290 (13 in Wild Type peptide)
Alignment
Wild Type:
"SSNALWEVEVVHHDPCRGGAGHWNG
||||||||||||.||||||||||||
Mutant:
SSNALWEVEVVHNDPCRGGAGHWNG"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay