Immunogenicity 14339
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
PCSK7
Transcript ID
NM_004716
HLA INFO
C*07:02
TCR INFO
No TCR info found!
Full length protein sequence (785 aa)
MPKGR
1
QKVPH
6
LDAPL
11
GLPTC
16
LWLEL
21
AGLFL
26
LVPWV
31
MGLAG
36
TGGPD
41
GQGTG
46
GPSWA
51
VHLES
56
LEGDG
61
EEETL
66
EQQAD
71
ALAQA
76
AGLVN
81
AGRIG
86
ELQGH
91
YLFVQ
96
PAGHR
101
PALEV
106
EAIRQ
111
QVEAV
116
LAGHE
121
AVRWH
126
SEQRL
131
LRRAK
136
RSVHF
141
NDPKY
146
PQQWH
151
LNNRR
156
SPGRD
161
INVTG
166
VWERN
171
VTGRG
176
VTVVV
181
VDDGV
186
EHTIQ
191
DIAPN
196
YSPEG
201
SYDLN
206
SNDPD
211
PMPHP
216
DVENG
221
NHHGT
226
RCAGE
231
IAAVP
236
NNSFC
241
AVGVA
246
YGSRI
251
AGIRV
256
LDGPL
261
TDSME
266
AVAFN
271
KHYQI
276
NDIYS
281
CSWGP
286
DDDGK
291
TVDGP
296
HQLGK
301
AALQH
306
GVIAG
311
RQGFG
316
SIFVV
321
ASGNG
326
GQHND
331
NCNYD
336
GYANS
341
IYTVT
346
IGAVD
351
EEGRM
356
PFYAE
361
ECASM
366
LAVTF
371
SGGDK
376
MLRSI
381
VTTDW
386
DLQKG
391
TGCTE
396
GHTGT
401
SAAAP
406
LAAGM
411
IALML
416
QVRPC
421
LTWRD
426
VQHII
431
VFTAT
436
RYEDR
441
RAEWV
446
TNEAG
451
FSHSH
456
QHGFG
461
LLNAW
466
RLVNA
471
AKIWT
476
SVPYL
481
ASYVS
486
PVLKE
491
NKAIP
496
QSPRS
501
LEVLW
506
NVSRM
511
DLEMS
516
GLKTL
521
EHVAV
526
TVSIT
531
HPRRG
536
SLELK
541
LFCPS
546
GMMSL
551
IGAPR
556
SMDSD
561
PNGFN
566
DWTFS
571
TVRCW
576
GERAR
581
GTYRL
586
VIRDV
591
GDESF
596
QVGIL
601
RQWQL
606
TLYGS
611
VWSAV
616
DIRDR
621
QRLLE
626
SAMSG
631
KYLHD
636
DFALP
641
CPPGL
646
KIPEE
651
DGYTI
656
TPNTL
661
KTLVL
666
VGCFT
671
VFWTV
676
YYMLE
681
VYLSQ
686
RNVAS
691
NQVCR
696
SGPCH
701
WPHRS
706
RKAKE
711
EGTEL
716
ESVPL
721
CSSKD
726
PDEVE
731
TESRG
736
PPTTS
741
DLLAP
746
DLLEQ
751
GDWSL
756
SQNKS
761
ALDCP
766
HQHLD
771
VPHGK
776
EEQIC
781
Mutation Information
DNA mutation:
None
Peptide Range:
2 ~ 26
Mut AA position:
14 (13 in Wild Type peptide)
Alignment
Wild Type:
"PKGRQKVPHLDAPLGLPTCLWLELA
||||||||||||.||||||||||||
Mutant:
PKGRQKVPHLDALLGLPTCLWLELA"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) PCSK7
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay