Immunogenicity 14347
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SEC31A
Transcript ID
NM_016211
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (1181 aa)
MKLKE
1
VDRTA
6
MQAWS
11
PAQNH
16
PIYLA
21
TGTSA
26
QQLDA
31
TFSTN
36
ASLEI
41
FELDL
46
SDPSL
51
DMKSC
56
ATFSS
61
SHRYH
66
KLIWG
71
PYKMD
76
SKGDV
81
SGVLI
86
AGGEN
91
GNIIL
96
YDPSK
101
IIAGD
106
KEVVI
111
AQNDK
116
HTGPV
121
RALDV
126
NIFQT
131
NLVAS
136
GANES
141
EIYIW
146
DLNNF
151
ATPMT
156
PGAKT
161
QPPED
166
ISCIA
171
WNRQV
176
QHILA
181
SASPS
186
GRATV
191
WDLRK
196
NEPII
201
KVSDH
206
SNRMH
211
CSGLA
216
WHPDV
221
ATQMV
226
LASED
231
DRLPV
236
IQMWD
241
LRFAS
246
SPLRV
251
LENHA
256
RGILA
261
IAWSM
266
ADPEL
271
LLSCG
276
KDAKI
281
LCSNP
286
NTGEV
291
LYELP
296
TNTQW
301
CFDIQ
306
WCPRN
311
PAVLS
316
AASFD
321
GRISV
326
YSIMG
331
GSTDG
336
LRQKQ
341
VDKLS
346
SSFGN
351
LDPFG
356
TGQPL
361
PPLQI
366
PQQTA
371
QHSIV
376
LPLKK
381
PPKWI
386
RRPVG
391
ASFSF
396
GGKLV
401
TFENV
406
RMPSH
411
QGAEQ
416
QQQQH
421
HVFIS
426
QVVTE
431
KEFLS
436
RSDQL
441
QQAVQ
446
SQGFI
451
NYCQK
456
KIDAS
461
QTEFE
466
KNVWS
471
FLKVN
476
FEDDS
481
RGKYL
486
ELLGY
491
RKEDL
496
GKKHI
501
KEEKE
506
ESEFL
511
PSSGG
516
TFNIS
521
VSGDI
526
DGLIT
531
QALLT
536
GNFES
541
AVDLC
546
LHDNR
551
MADAI
556
ILAIA
561
GGQEL
566
LARTQ
571
KKYFA
576
KSQSK
581
ITRLI
586
TAVVM
591
KNWKE
596
IVESC
601
DLKNW
606
REALA
611
AVLTY
616
AKPDE
621
FSALC
626
DLLGT
631
RLENE
636
GDSLL
641
QTQAC
646
LCYIC
651
AGNVE
656
KLVAC
661
WTKAQ
666
DGSHP
671
LSLQD
676
LIEKV
681
VILRK
686
AVQLT
691
QAMDT
696
STVGV
701
LLAAK
706
MSQYA
711
NLLAA
716
QGSIA
721
AALAF
726
LPDNT
731
NQPNI
736
MQLRD
741
RLCRA
746
QGEPV
751
AGHES
756
PKIPY
761
EKQQL
766
PKGRP
771
GPVAG
776
HHQMP
781
RVQTQ
786
QYYPH
791
GENPP
796
PPGFI
801
MHGNV
806
NPNAA
811
GQLPT
816
SPGHM
821
HTQVP
826
PYPQP
831
QPYQP
836
AQPYP
841
FGTGG
846
SAMYR
851
PQQPV
856
APPTS
861
NAYPN
866
TPYIS
871
SASSY
876
TGQSQ
881
LYAAQ
886
HQASS
891
PTSSP
896
ATSFP
901
PPPSS
906
GASFQ
911
HGGPG
916
APPSS
921
SAYAL
926
PPGTT
931
GTLPA
936
ASELP
941
ASQRT
946
GPQNG
951
WNDPP
956
ALNRV
961
PKKKK
966
MPENF
971
MPPVP
976
ITSPI
981
MNPLG
986
DPQSQ
991
MLQQQ
996
PSAPV
1001
PLSSQ
1006
SSFPQ
1011
PHLPG
1016
GQPFH
1021
GVQQP
1026
LGQTG
1031
MPPSF
1036
SKPNI
1041
EGAPG
1046
APIGN
1051
TFQHV
1056
QSLPT
1061
KKITK
1066
KPIPD
1071
EHLIL
1076
KTTFE
1081
DLIQR
1086
CLSSA
1091
TDPQT
1096
KRKLD
1101
DASKR
1106
LEFLY
1111
DKLRE
1116
QTLSP
1121
TITSG
1126
LHNIA
1131
RSIET
1136
RNYSE
1141
GLTMH
1146
THIVS
1151
TSNFS
1156
ETSAF
1161
MPVLK
1166
VVLTQ
1171
ANKLG
1176
V
1181
Mutation Information
DNA mutation:
None
Peptide Range:
423 ~ 447
Mut AA position:
435 (13 in Wild Type peptide)
Alignment
Wild Type:
"QQHHVFISQVVTEKEFLSRSDQLQQ
||||||||||||.||||||||||||
Mutant:
QQHHVFISQVVTKKEFLSRSDQLQQ"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) SEC31A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay