Immunogenicity 14354
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
DCLRE1A
Transcript ID
NM_001271816
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1040 aa)
MLEDI
1
SEEDI
6
WEYKS
11
KRKPK
16
RVDPN
21
NGSKN
26
ILKSV
31
EKATD
36
GKYQS
41
KRSRN
46
RKRAA
51
EAKEV
56
KDHEV
61
PLGNA
66
GCQTS
71
VASSQ
76
NSSCG
81
DGIQQ
86
TQDKE
91
TTPGK
96
LCRTQ
101
KSQHV
106
SPKIR
111
PVYDG
116
YCPNC
121
QMPFS
126
SLIGQ
131
TPRWH
136
VFECL
141
DSPPR
146
SETEC
151
PDGLL
156
CTSTI
161
PFHYK
166
RYTHF
171
LLAQS
176
RAGDH
181
PFSSP
186
SPASG
191
GSFSE
196
TKSGV
201
LCSLE
206
ERWSS
211
YQNQT
216
DNSVS
221
NDPLL
226
MTQYF
231
KKSPS
236
LTEAS
241
EKIST
246
HIQTS
251
QQALQ
256
FTDFV
261
ENDKL
266
VGVAL
271
RLANN
276
SEHIN
281
LPLPE
286
NDFSD
291
CEISY
296
SPLQS
301
DEDTH
306
DIDEK
311
PDDSQ
316
EQLFF
321
TESSK
326
DGSLE
331
EDDDS
336
CGFFK
341
KRHGP
346
LLKDQ
351
DESCP
356
KVNSF
361
LTRDK
366
YDEGL
371
YRFNS
376
LNDLS
381
QPISQ
386
NNEST
391
LPYDL
396
ACTGG
401
DFVLF
406
PPALA
411
GKLAA
416
SVHQA
421
TKAKP
426
DEPEF
431
HSAQS
436
NKQKQ
441
VIEES
446
SVYNQ
451
VSLPL
456
VKSLM
461
LKPFE
466
SQVEG
471
YLSSQ
476
PTQNT
481
IRKLS
486
SENLN
491
AKNNT
496
NSACF
501
CRKAL
506
EGVPV
511
GKATI
516
LNTEN
521
LSSTP
526
APKYL
531
KILPS
536
GLKYN
541
ARHPS
546
TKVMK
551
QMDIG
556
VYFGL
561
PPKRK
566
EEKLL
571
GESAL
576
EGINL
581
NPVPS
586
PNQKR
591
SSQCK
596
RKAEK
601
SLSDL
606
EFDAS
611
TLHES
616
QLSVE
621
LSSER
626
SQRQK
631
KRCRK
636
SNSLQ
641
EGACQ
646
KRSDH
651
LINTE
656
SEAVN
661
LSKVK
666
VFTKS
671
AHGGL
676
QRGNK
681
KIPES
686
SNVGG
691
SRKKT
696
CPFYK
701
KIPGT
706
GFTVD
711
AFQYG
716
VVEGC
721
TAYFL
726
THFHS
731
DHYAG
736
LSKHF
741
TFPVY
746
CSEIT
751
GNLLK
756
NKLHV
761
QEQYI
766
HPLPL
771
DTECI
776
VNGVK
781
VVLLD
786
ANHCP
791
GAVMI
796
LFYLP
801
NGTVI
806
LHTGD
811
FRADP
816
SMERS
821
LLADQ
826
KVHML
831
YLDTT
836
YCSPE
841
YTFPS
846
QQEVI
851
RFAIN
856
TAFEA
861
VTLNP
866
HALVV
871
CGTYS
876
IGKEK
881
VFLAI
886
ADVLG
891
SKVGM
896
SQEKY
901
KTLQC
906
LNIPE
911
INSLI
916
TTDMC
921
SSLVH
926
LLPMM
931
QINFK
936
GLQSH
941
LKKCG
946
GKYNQ
951
ILAFR
956
PTGWT
961
HSNKF
966
TRIAD
971
VIPQT
976
KGNIS
981
IYGIP
986
YSEHS
991
SYLEM
996
KRFVQ
1001
WLKPQ
1006
KIIPT
1011
VNVGT
1016
WKSRS
1021
TMEKY
1026
FREWK
1031
LEAGY
1036
Mutation Information
DNA mutation:
None
Peptide Range:
997 ~ 1021
Mut AA position:
1009 (13 in Wild Type peptide)
Alignment
Wild Type:
"YLEMKRFVQWLKPQKIIPTVNVGTW
||||||||||||.||||||||||||
Mutant:
YLEMKRFVQWLKHQKIIPTVNVGTW"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) DCLRE1A
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay