Immunogenicity 14444

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ALMS1
Transcript ID
NM_015120
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (4169 aa)
MEPED
1
LPWPG
6
ELEEE
11
EEEEE
16
EEEEE
21
EEEEA
26
AAAAA
31
ANVDD
36
VVVVE
41
EVEEE
46
AGREL
51
DSDSH
56
YGPQH
61
LESID
66
DEEDE
71
EAKAW
76
LQAHP
81
GRILP
86
PLSPP
91
QHRYS
96
EGERT
101
SLEKI
106
VPLTC
111
HVWQQ
116
IVYQG
121
NSRTQ
126
ISDTN
131
VVCLE
136
TTAQR
141
GSGDD
146
QKTES
151
WHCLP
156
QEMDS
161
SQTLD
166
TSQTR
171
FNVRT
176
EDTEV
181
TDFPS
186
LEEGI
191
LTQSE
196
NQVKE
201
PNRDL
206
FCSPL
211
LVIQD
216
SFASP
221
DLPLL
226
TCLTQ
231
DQEFA
236
PDSLF
241
HQSEL
246
SFAPL
251
RGIPD
256
KSEDT
261
EWSSR
266
PSEVS
271
EALFQ
276
ATAEV
281
ASDLA
286
SSRFS
291
VSQHP
296
LIGST
301
AVGSQ
306
CPFLP
311
SEQGN
316
NEETI
321
SSVDE
326
LKIPK
331
DCDRY
336
DDLCS
341
YMSWK
346
TRKDT
351
QWPEN
356
NLADK
361
DQVSV
366
ATSFD
371
ITDEN
376
IATKR
381
SDHFD
386
AARSY
391
GQYWT
396
QEDSS
401
KQAET
406
YLTKG
411
LQGKV
416
ESDVI
421
TLDGL
426
NENAV
431
VCSER
436
VAELQ
441
RKPTR
446
ESEYH
451
SSDLR
456
MLRMS
461
PDTVP
466
KAPKH
471
LKAGD
476
TSKGG
481
IAKVT
486
QSNLK
491
SGITT
496
TPVDS
501
DIGSH
506
LSLSL
511
EDLSQ
516
LAVSS
521
PLETT
526
TGQHT
531
DTLNQ
536
KTLAD
541
THLTE
546
ETLKV
551
TAIPE
556
PADQK
561
TATPT
566
VLSSS
571
HSHRG
576
KPSIF
581
YQQGL
586
PDSHL
591
TEEAL
596
KVSAA
601
PGLAD
606
QTTGM
611
STLTS
616
TSYSH
621
REKPG
626
TFYQQ
631
ELPES
636
NLTEE
641
PLEVS
646
AAPGP
651
VEQKT
656
GIPTV
661
SSTSH
666
SHVED
671
LLFFY
676
RQTLP
681
DGHLT
686
DQALK
691
VSAVS
696
GPADQ
701
KTGTA
706
TVLST
711
PHSHR
716
EKPGI
721
FYQQE
726
FADSH
731
QTEET
736
LTKVS
741
ATPGP
746
ADQKT
751
EIPAV
756
QSSSY
761
SQREK
766
PSILY
771
PQDLA
776
DSHLP
781
EEGLK
786
VSAVA
791
GPADQ
796
KTGLP
801
TVPSS
806
AYSHR
811
EKLLV
816
FYQQA
821
LLDSH
826
LPEEA
831
LKVSA
836
VSGPA
841
DGKTG
846
TPAVT
851
STSSA
856
SSSLG
861
EKPSA
866
FYQQT
871
LPNSH
876
LTEEA
881
LKVSI
886
VPGPG
891
DQKTG
896
IPSAP
901
SSFYS
906
HREKP
911
IIFSQ
916
QTLPD
921
FLFPE
926
EALKV
931
SAVSV
936
LAAQK
941
TGTPT
946
VSSNS
951
HSHSE
956
KSSVF
961
YQQEL
966
PDSDL
971
PRESL
976
KMSAI
981
PGLTD
986
QKTVP
991
TPTVP
996
SGSFS
1001
HREKP
1006
SIFYQ
1011
QEWPD
1016
SYATE
1021
KALKV
1026
STGPG
1031
PADQK
1036
TEIPA
1041
VQSSS
1046
YPQRE
1051
KPSVL
1056
YPQVL
1061
SDSHL
1066
PEESL
1071
KVSAF
1076
PGPAD
1081
QMTDT
1086
PAVPS
1091
TFYSQ
1096
REKPG
1101
IFYQQ
1106
TLPES
1111
HLPKE
1116
ALKIS
1121
VAPGL
1126
ADQKT
1131
GTPTV
1136
TSTSY
1141
SQHRE
1146
KPSIF
1151
HQQAL
1156
PGTHI
1161
PEEAQ
1166
KVSAV
1171
TGPGN
1176
QKTWI
1181
PRVLS
1186
TFYSQ
1191
REKPG
1196
IFYQQ
1201
TLPGS
1206
HIPEE
1211
AQKVS
1216
PVLGP
1221
ADQKT
1226
GTPTP
1231
TSASY
1236
SHTEK
1241
PGIFY
1246
QQVLP
1251
DNHPT
1256
EEALK
1261
ISVAS
1266
EPVDQ
1271
TTGTP
1276
AVTST
1281
SYSQY
1286
REKPS
1291
IFYQQ
1296
SLPSS
1301
HLTEE
1306
AKNVS
1311
AVPGP
1316
ADQKT
1321
VIPIL
1326
PSTFY
1331
SHTEK
1336
PGVFY
1341
QQVLP
1346
HSHPT
1351
EEALK
1356
ISVAS
1361
EPVDQ
1366
TTGTP
1371
TVTST
1376
SYSQH
1381
TEKPS
1386
IFYQQ
1391
SLPGS
1396
HLTEE
1401
AKNVS
1406
AVPGP
1411
GDRKT
1416
GIPTL
1421
PSTFY
1426
SHTEK
1431
PGSFY
1436
QQVLP
1441
HSHLP
1446
EEALE
1451
VSVAP
1456
GPVDQ
1461
TIGTP
1466
TVTSP
1471
SSSFG
1476
EKPIV
1481
IYKQA
1486
FPEGH
1491
LPEES
1496
LKVSV
1501
APGPV
1506
GQTTG
1511
APTIT
1516
SPSYS
1521
QHRAK
1526
SGSFY
1531
QLALL
1536
GSQIP
1541
EEALR
1546
VSSAP
1551
GPADQ
1556
TTGIP
1561
TITST
1566
SYSFG
1571
EKPIV
1576
NYKQA
1581
FPDGH
1586
LPEEA
1591
LKVSI
1596
VSGPT
1601
EKKTD
1606
IPAGP
1611
LGSSA
1616
LGEKP
1621
ITFYR
1626
QALLD
1631
SPLNK
1636
EVVKV
1641
SAAPG
1646
PADQK
1651
TETLP
1656
VHSTS
1661
YSNRG
1666
KPVIF
1671
YQQTL
1676
SDSHL
1681
PEEAL
1686
KVPPV
1691
PGPDA
1696
QKTET
1701
PSVSS
1706
SLYSY
1711
REKPI
1716
VFYQQ
1721
ALPDS
1726
ELTQE
1731
ALKVS
1736
AVPQP
1741
ADQKT
1746
GLSTV
1751
TSSFY
1756
SHTEK
1761
PNISY
1766
QQELP
1771
DSHLT
1776
EEALK
1781
VSNVP
1786
GPADQ
1791
KTGVS
1796
TVTST
1801
SYSHR
1806
EKPIV
1811
SYQRE
1816
LPHFT
1821
EAGLK
1826
ILRVP
1831
GPADQ
1836
KTGIN
1841
ILPSN
1846
SYPQR
1851
EHSVI
1856
SYEQE
1861
LPDLT
1866
EVTLK
1871
AIGVP
1876
GPADQ
1881
KTGIQ
1886
IASSS
1891
SYSNR
1896
EKASI
1901
FHQQE
1906
LPDVT
1911
EEALN
1916
VFVVP
1921
GQGDR
1926
KTEIP
1931
TVPLS
1936
YYSRR
1941
EKPSV
1946
ISQQE
1951
LPDSH
1956
LTEEA
1961
LKVSP
1966
VSIPA
1971
EQKTG
1976
IPIGL
1981
SSSYS
1986
HSHKE
1991
KLKIS
1996
TVHIP
2001
DDQKT
2006
EFPAA
2011
TLSSY
2016
SQIEK
2021
PKIST
2026
VIGPN
2031
DQKTP
2036
SQTAF
2041
HSSYS
2046
QTVKP
2051
NILFQ
2056
QQLPD
2061
RDQSK
2066
GILKI
2071
SAVPE
2076
LTDVN
2081
TGKPV
2086
SLSSS
2091
YFHRE
2096
KSNIF
2101
SPQEL
2106
PGSHV
2111
TEDVL
2116
KVSTI
2121
PGPAG
2126
QKTVL
2131
PTALP
2136
SSFSH
2141
REKPD
2146
IFYQK
2151
DLPDR
2156
HLTED
2161
ALKIS
2166
SALGQ
2171
ADQIT
2176
GLQTV
2181
PSGTY
2186
SHGEN
2191
HKLVS
2196
EHVQR
2201
LIDNL
2206
NSSDS
2211
SVSSN
2216
NVLLN
2221
SQADD
2226
RVVIN
2231
KPESA
2236
GFRDV
2241
GSEEI
2246
QDAEN
2251
SAKTL
2256
KEIRT
2261
LLMEA
2266
ENMAL
2271
KRCNF
2276
PAPLA
2281
RFRDI
2286
SDISF
2291
IQSKK
2296
VVCFK
2301
EPSST
2306
GVSNG
2311
DLLHR
2316
QPFTE
2321
ESPSS
2326
RCIQK
2331
DIGTQ
2336
TNLKC
2341
RRGIE
2346
NWEFI
2351
SSTTV
2356
RSPLQ
2361
EAESK
2366
VSMAL
2371
EETLR
2376
QYQAA
2381
KSVMR
2386
SEPEG
2391
CSGTI
2396
GNKII
2401
IPMMT
2406
VIKSD
2411
SSSDA
2416
SDGNG
2421
SCSWD
2426
SNLPE
2431
SLESV
2436
SDVLL
2441
NFFPY
2446
VSPKT
2451
SITDS
2456
REEEG
2461
VSESE
2466
DGGGS
2471
SVDSL
2476
AAHVK
2481
NLLQC
2486
ESSLN
2491
HAKEI
2496
LRNAE
2501
EEESR
2506
VRAHA
2511
WNMKF
2516
NLAHD
2521
CGYSI
2526
SELNE
2531
DDRRK
2536
VEEIK
2541
AELFG
2546
HGRTT
2551
DLSKG
2556
LQSPR
2561
GMGCK
2566
PEAVC
2571
SHIII
2576
ESHEK
2581
GCFRT
2586
LTSEH
2591
PQLDR
2596
HPCAF
2601
RSAGP
2606
SEMTR
2611
GRQNP
2616
SSCRA
2621
KHVNL
2626
SASLD
2631
QNNSH
2636
FKVWN
2641
SLQLK
2646
SHSPF
2651
QNFIP
2656
DEFKI
2661
SKGLR
2666
MPFDE
2671
KMDPW
2676
LSELV
2681
EPAFV
2686
PPKEV
2691
DFHSS
2696
SQMPS
2701
PEPMK
2706
KFTTS
2711
ITFSS
2716
HRHSK
2721
CISNS
2726
SVVKV
2731
GVTEG
2736
SQCTG
2741
ASVGV
2746
FNSHF
2751
TEEQN
2756
PPRDL
2761
KQKTS
2766
SPSSF
2771
KMHSN
2776
SQDKE
2781
VTILA
2786
EGRRQ
2791
SQKLP
2796
VDFER
2801
SFQEE
2806
KPLER
2811
SDFTG
2816
SHSEP
2821
STRAN
2826
CSNFK
2831
EIQIS
2836
DNHTL
2841
ISMGR
2846
PSSTL
2851
GVNRS
2856
SSRLG
2861
VKEKN
2866
VTITP
2871
DLPSC
2876
IFLEQ
2881
RELFE
2886
QSKAP
2891
RADDH
2896
VRKHH
2901
SPSPQ
2906
HQDYV
2911
APDLP
2916
SCIFL
2921
EQREL
2926
FEQCK
2931
APYVD
2936
HQMRE
2941
NHSPL
2946
PQGQD
2951
SIASD
2956
LPSPI
2961
SLEQC
2966
QSKAP
2971
GVDDQ
2976
MNKHH
2981
FPLPQ
2986
GQDCV
2991
VEKNN
2996
QHKPK
3001
SHISN
3006
INVEA
3011
KFNTV
3016
VSQSA
3021
PNHCT
3026
LAASA
3031
STPPS
3036
NRKAL
3041
SCVHI
3046
TLCPK
3051
TSSKL
3056
DSGTL
3061
DERFH
3066
SLDAA
3071
SKARM
3076
NSEFN
3081
FDLHT
3086
VSSRS
3091
LEPTS
3096
KLLTS
3101
KPVAQ
3106
DQESL
3111
GFLGP
3116
KSSLD
3121
FQVVQ
3126
PSLPD
3131
SNTIT
3136
QDLKT
3141
IPSQN
3146
SQIVT
3151
SRQIQ
3156
VNISD
3161
FEGHS
3166
NPEGT
3171
PVFAD
3176
RLPEK
3181
MKTPL
3186
SAFSE
3191
KLSSD
3196
AVTQI
3201
TTESP
3206
EKTLF
3211
SSEIF
3216
INAED
3221
RGHEI
3226
IEPGN
3231
QKLRK
3236
APVKF
3241
ASSSS
3246
VQQVT
3251
FSRGT
3256
DGQPL
3261
LLPYK
3266
PSGST
3271
KMYYV
3276
PQLRQ
3281
IPPSP
3286
DSKSD
3291
TTVES
3296
SHSGS
3301
NDAIA
3306
PDFPA
3311
QVLGT
3316
RDDDL
3321
SATVN
3326
IKHKE
3331
GIYSK
3336
RVVTK
3341
ASLPV
3346
GEKPL
3351
QNENA
3356
DASVQ
3361
VLITG
3366
DENLS
3371
DKKQQ
3376
EIHST
3381
RAVTE
3386
AAQAK
3391
EKESL
3396
QKDTA
3401
DSSAA
3406
AAAEH
3411
SAQVG
3416
DPEMK
3421
NLPDT
3426
KAITQ
3431
KEEIH
3436
RKKTV
3441
PEEAW
3446
PNNKE
3451
SLQIN
3456
IEESE
3461
CHSEF
3466
ENTTR
3471
SVFRS
3476
AKFYI
3481
HHPVH
3486
LPSDQ
3491
DICHE
3496
SLGKS
3501
VFMRH
3506
SWKDF
3511
FQHHP
3516
DKHRE
3521
HMCLP
3526
LPYQN
3531
MDKTK
3536
TDYTR
3541
IKSLS
3546
INVNL
3551
GNKEV
3556
MDTTK
3561
SQVRD
3566
YPKHN
3571
GQISD
3576
PQRDQ
3581
KVTPE
3586
QTTQH
3591
TVSLN
3596
ELWNK
3601
YRERQ
3606
RQQRQ
3611
PELGD
3616
RKELS
3621
LVDRL
3626
DRLAK
3631
ILQNP
3636
ITHSL
3641
QVSES
3646
THDDS
3651
RGERS
3656
VKEWS
3661
GRQQQ
3666
RNKLQ
3671
KKKRF
3676
KSLEK
3681
SHKNT
3686
GELKK
3691
SKVLS
3696
HHRAG
3701
RSNQI
3706
KIEQI
3711
KFDKY
3716
ILSKQ
3721
PGFNY
3726
ISNTS
3731
SDCRP
3736
SEESE
3741
LLTDT
3746
TTNIL
3751
SGTTS
3756
TVESD
3761
ILTQT
3766
DREVA
3771
LHERS
3776
SSVST
3781
IDTAR
3786
LIQAF
3791
GHERV
3796
CLSPR
3801
RIKLY
3806
SSITN
3811
QQRRY
3816
LEKRS
3821
KHSKK
3826
VLNTG
3831
HPLVT
3836
SEHTR
3841
RRHIQ
3846
VANHV
3851
ISSDS
3856
ISSSA
3861
SSFLS
3866
SNSTF
3871
CNKQN
3876
VHMLN
3881
KGIQA
3886
GNLEI
3891
VNGAK
3896
KHTRD
3901
VGITF
3906
PTPSS
3911
SEAKL
3916
EENSD
3921
VTSWS
3926
EEKRE
3931
EKMLF
3936
TGYPE
3941
DRKLK
3946
KNKKN
3951
SHEGV
3956
SWFVP
3961
VENVE
3966
SRSKK
3971
ENVPN
3976
TCGPG
3981
ISWFE
3986
PITKT
3991
RPWRE
3996
PLREQ
4001
NCQGQ
4006
HLDGR
4011
GYLAG
4016
PGREA
4021
GRDLL
4026
RPFVR
4031
ATLQE
4036
SLQFH
4041
RPDFI
4046
SRSGE
4051
RIKRL
4056
KLIVQ
4061
ERKLQ
4066
SMLQT
4071
ERDAL
4076
FNIDR
4081
ERQGH
4086
QNRMC
4091
PLPKR
4096
VFLAI
4101
QKNKP
4106
ISKKE
4111
MIQRS
4116
KRIYE
4121
QLPEV
4126
QKKRE
4131
EEKRK
4136
SEYKS
4141
YRLRA
4146
QLYKK
4151
RVTNQ
4156
LLGRK
4161
VPWD
4166
Mutation Information
DNA mutation:
None
Peptide Range:
880 ~ 904
Mut AA position:
892 (13 in Wild Type peptide)
Alignment
Wild Type:
"HLTEEALKVSIVPGPGDQKTGIPSA
||||||||||||.||||||||||||
Mutant:
HLTEEALKVSIVFGPGDQKTGIPSA"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay