Immunogenicity 14457
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
BRAT1
Transcript ID
NM_152743
HLA INFO
C*07:02
TCR INFO
No TCR info found!
Full length protein sequence (821 aa)
MDPEC
1
AQLLP
6
ALCAV
11
LVDPR
16
QPVAD
21
DTCLE
26
KLLDW
31
FKTVT
36
EGESS
41
VVLLQ
46
EHPCL
51
VELLS
56
HVLKV
61
QDLSS
66
GVLSF
71
SLRLA
76
GTFAA
81
QENCF
86
QYLQQ
91
GELLP
96
GLFGE
101
PGPLG
106
RATWA
111
VPTVR
116
SGWIQ
121
GLRSL
126
AQHPS
131
ALRFL
136
ADHGA
141
VDTIF
146
SLQGD
151
SSLFV
156
ASAAS
161
QLLVH
166
VLALS
171
MRGGA
176
EGQPC
181
LPGGD
186
WPACA
191
QKIMD
196
HVEES
201
LCSAA
206
TPKVT
211
QALNV
216
LTTTF
221
GRCQS
226
PWTEA
231
LWVRL
236
SPRVA
241
CLLER
246
DPIPA
251
AHSFV
256
DLLLC
261
VARSP
266
VFSSS
271
DGSLW
276
ETVAR
281
ALSCL
286
GPTHM
291
GPLAL
296
GILKL
301
EHCPQ
306
ALRTQ
311
AFQVL
316
LQPLA
321
CVLKA
326
TVQAP
331
GPPGL
336
LDGTA
341
DDATT
346
VDTLL
351
ASKSS
356
CAGLL
361
CRTLA
366
HLEEL
371
QPLPQ
376
RPSPW
381
PQASL
386
LGATV
391
TVLRL
396
CDGSA
401
APASS
406
VGGHL
411
CGTLA
416
GCVRV
421
QRAAL
426
DFLGT
431
LSQGT
436
GPQEL
441
VTQAL
446
AVLLE
451
CLESP
456
GSSPT
461
VLKKA
466
FQATL
471
RWLLS
476
SPKTP
481
GCSDL
486
GPLIP
491
QFLRE
496
LFPVL
501
QKRLC
506
HPCWE
511
VRDSA
516
LEFLT
521
QLSRH
526
WGGQA
531
DFRCA
536
LLASE
541
VPQLA
546
LQLLQ
551
DPESY
556
VRASA
561
VTAMG
566
QLSSQ
571
GLHAP
576
TSPEH
581
AEARQ
586
SLFLE
591
LLHIL
596
SVDSE
601
GFPRR
606
AVMQV
611
FTEWL
616
RDGHA
621
DAAQD
626
TEQFV
631
ATVLQ
636
AASRD
641
LDWEV
646
RAQGL
651
ELALV
656
FLGQT
661
LGPPR
666
THCPY
671
AVALP
676
EVAPA
681
QPLTE
686
ALRAL
691
CHVGL
696
FDFAF
701
CALFD
706
CDRPV
711
AQKSC
716
DLLLF
721
LRDKI
726
ASYSS
731
LREAR
736
GSPNT
741
ASAEA
746
TLPRW
751
RAGEQ
756
AQPPG
761
DQEPE
766
AVLAM
771
LRSLD
776
LEGLR
781
STLAE
786
SSDHV
791
EKSPQ
796
SLLQD
801
MLATG
806
GFLQG
811
DEADC
816
Y
821
Mutation Information
DNA mutation:
None
Peptide Range:
406 ~ 430
Mut AA position:
418 (13 in Wild Type peptide)
Alignment
Wild Type:
"APASSVGGHLCGTLAGCVRVQRAAL
||||||||||||.||||||||||||
Mutant:
APASSVGGHLCGILAGCVRVQRAAL"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) BRAT1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay