Immunogenicity 14462
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
C2CD3
Transcript ID
NM_015531
HLA INFO
A*01:01
TCR INFO
No TCR info found!
Full length protein sequence (1963 aa)
MKQRK
1
GQGSG
6
GSRGR
11
KKRGL
16
SDISP
21
STSLP
26
PLVEG
31
QLRCF
36
LKLTV
41
NRVIW
46
KIAKP
51
PTCVL
56
VRVRW
61
WGETS
66
DGTLF
71
CPRDA
76
LQTEP
81
KAVRT
86
TTRYA
91
IRCGP
96
KQFTS
101
YLTDM
106
AVLVL
111
EVITK
116
LDGLP
121
IGRVQ
126
INGLA
131
QLSPT
136
HQING
141
FFTIV
146
SSTSK
151
KLGEL
156
QVSLA
161
LEPLS
166
ETYDS
171
YHPLP
176
TTDMT
181
ENVLL
186
SKQGF
191
RENTE
196
PSSTQ
201
FQVPS
206
RPRDI
211
HTIKI
216
DGKEL
221
AANSS
226
RSTTP
231
RGKDH
236
VCFAE
241
NPDTI
246
KDSSF
251
GLQHS
256
LNSGQ
261
SLESV
266
TLKGR
271
APRKQ
276
MSLLN
281
SSEFQ
286
PQIRT
291
VAKSH
296
SDSCI
301
LSSNN
306
LPTKD
311
LLSAL
316
LEQGN
321
KLRNA
326
MVISA
331
MKSSP
336
ETSML
341
LDQVH
346
PPINE
351
DSLRA
356
STQIR
361
AFSRN
366
RFKDH
371
IEDHL
376
LPSTE
381
NTFWR
386
HDTKA
391
DTRAI
396
QLLLG
401
SAELS
406
QGNFW
411
DGLGS
416
PPDSP
421
SPGSD
426
VYCIS
431
ELNDP
436
QYDQS
441
LLENL
446
FYTAP
451
KSDTS
456
ISDFL
461
SEEDD
466
IVPSK
471
KISQS
476
TALAR
481
SSKVL
486
ESSDH
491
KLKKR
496
SAGKR
501
NRNLV
506
EQQML
511
SETPE
516
DAQTM
521
TLSVD
526
RLALL
531
GRTHS
536
VRIII
541
ETMGV
546
PPDSP
551
QMTPG
556
KKSYA
561
GPPPK
566
VTTAK
571
KRTFF
576
VEYHF
581
PVGFS
586
ESGLG
591
KTALI
596
TEVVR
601
LASSK
606
ITDGK
611
VKFQQ
616
RFVFP
621
VQFGG
626
PMIEH
631
WWNSN
636
LTFQI
641
YVKKT
646
PQKKP
651
EVIGS
656
VSLSL
661
RAVIQ
666
SELLS
671
FSDQL
676
PVQQE
681
NGQSP
686
FGPLK
691
VTMEL
696
ITDNK
701
DFTGI
706
NTKLS
711
GNTHY
716
TPLCA
721
PTSPN
726
KALPE
731
LNQDM
736
TCTKN
741
PQNLN
746
QIHEE
751
TAKKA
756
QNLVL
761
PNRKS
766
PSPVA
771
PHPST
776
FVATP
781
ASHNL
786
VNQTN
791
GTTKE
796
SALLL
801
HVLLM
806
VPDGK
811
DFISG
816
ESEKQ
821
SPCNV
826
YLNCK
831
LFSTE
836
EVTRS
841
VIAWG
846
TTQPV
851
FNFSQ
856
VIPVS
861
LSSKY
866
LERLK
871
NNVMV
876
IETWN
881
KVRSP
886
GQDKL
891
LGLVK
896
LPLHQ
901
FYMSF
906
KDAKI
911
SRLLL
916
DAQYP
921
VVAVD
926
SYMPV
931
IDVFS
936
GHQNG
941
SLRVF
946
LAMGS
951
SNQIM
956
ALQRL
961
KNEEG
966
TLPPF
971
SPRPA
976
HFLDQ
981
PTAAS
986
VAMAE
991
DRGNG
996
LMEHC
1001
FEIHI
1006
EMVKG
1011
LAPLQ
1016
ATVWG
1021
EADCY
1026
VQYYF
1031
PVQHS
1036
QSSVL
1041
KGPEF
1046
LENGI
1051
TLKPF
1056
RTATT
1061
LCVPD
1066
PIFNS
1071
EHHHS
1076
LLLPA
1081
EVPVQ
1086
RLLLS
1091
AFSAQ
1096
GLVPG
1101
GGVQF
1106
EIWCR
1111
YYYPN
1116
VRDQK
1121
VAKGT
1126
LPLSR
1131
ICAMV
1136
TTQHR
1141
EDVGI
1146
QTFNL
1151
PLTPR
1156
IENRK
1161
ELRNQ
1166
SSGLL
1171
DVGLR
1176
YRRSP
1181
RTAEG
1186
VLAAR
1191
TVSIS
1196
VQIIR
1201
ACGLQ
1206
AAAKA
1211
LAERE
1216
PALQF
1221
SATVG
1226
VNASV
1231
TTHLS
1236
FLPQG
1241
EQRRT
1246
HPVAC
1251
SFCPE
1256
FSHHV
1261
EFTCN
1266
LVTQH
1271
CSGEA
1276
CFLAE
1281
LLEFA
1286
EVIFA
1291
VYHEN
1296
TKSAS
1301
DIISI
1306
ESCKE
1311
YLLGV
1316
VKVPT
1321
KELLI
1326
KRSGI
1331
TGWYP
1336
IILPE
1341
DGGLP
1346
HGLEL
1351
MQKIV
1356
GGLEL
1361
SISFT
1366
HRGDR
1371
ERVLE
1376
AAEHL
1381
GWSFE
1386
NSLKD
1391
FVRMD
1396
EGEPA
1401
TVTIS
1406
TPRLW
1411
LPIHC
1416
VLLAG
1421
HNHIH
1426
KNTYC
1431
YLRYK
1436
FYDHE
1441
AFWTP
1446
LKKPK
1451
ESVNK
1456
KQIMV
1461
TFKAS
1466
KRAEV
1471
TRGPS
1476
LLWYF
1481
REERL
1486
EIQVW
1491
RAYGN
1496
DSVER
1501
PHQTD
1506
SWIGS
1511
AYVDL
1516
ARLGE
1521
RSART
1526
LTVSG
1531
VYPLF
1536
GRNAS
1541
NLSGA
1546
ALRVH
1551
VVLSS
1556
LSSHL
1561
EPTHE
1566
LDSMD
1571
CSSHS
1576
ESEQL
1581
PRRND
1586
EVQLS
1591
PPEVI
1596
SCHQK
1601
SPAST
1606
QVPCS
1611
STTAE
1616
VRLTQ
1621
EGPAD
1626
LDGTF
1631
AVSIL
1636
VERAM
1641
HLSLK
1646
GSPLT
1651
ERKVS
1656
IPSCC
1661
VSFAT
1666
ADESS
1671
PVYTQ
1676
VVENT
1681
DSPIW
1686
NFQQQ
1691
SRLSK
1696
ELLLD
1701
PQQTL
1706
VFKVW
1711
HKGDE
1716
ERVIG
1721
FASVD
1726
LSPLL
1731
SGFQF
1736
VCGWY
1741
NITDF
1746
SGECQ
1751
GQIKV
1756
AVSPL
1761
ESLIH
1766
FKEER
1771
QARRG
1776
VETSK
1781
SLIPI
1786
YSPFS
1791
FPASD
1796
TYAAF
1801
SSHMA
1806
RQTLD
1811
QLAHA
1816
SSKEL
1821
DFSSP
1826
GRSDT
1831
TRSQA
1836
SRHEE
1841
HVQNI
1846
RRFHE
1851
SLHLQ
1856
GEAPL
1861
PCDDK
1866
LTTSP
1871
LSSQT
1876
SILTS
1881
LRKNL
1886
SELDQ
1891
IQRYF
1896
RQKLT
1901
KPFLP
1906
LSPQT
1911
QTAIS
1916
QHQES
1921
CRDHL
1926
GPGAS
1931
SLDPG
1936
SQCIL
1941
EKSSN
1946
LVLQV
1951
SSLIT
1956
GSY
1961
Mutation Information
DNA mutation:
None
Peptide Range:
474 ~ 498
Mut AA position:
486 (13 in Wild Type peptide)
Alignment
Wild Type:
"SKKISQSTALARSSKVLESSDHKLK
||||||||||||.||||||||||||
Mutant:
SKKISQSTALARLSKVLESSDHKLK"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) C2CD3
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay