Immunogenicity 14484
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
FREM1
Transcript ID
NM_144966
HLA INFO
B*07:01
TCR INFO
No TCR info found!
Full length protein sequence (2179 aa)
MNSLS
1
WGAAN
6
AVLLL
11
LLLAW
16
ASPTF
21
ISINR
26
GVRVM
31
KGHSA
36
FLSGD
41
DLKFA
46
IPKEK
51
DACKV
56
EVVMN
61
EPITQ
66
RVGKL
71
TPQVF
76
DCHFL
81
PNEVK
86
YVHNG
91
CPILD
96
EDTVK
101
LRLYR
106
FTERD
111
TFIET
116
FILWV
121
YLLEP
126
DCNII
131
HMSNN
136
VLEVP
141
EFNGL
146
SQAID
151
KNLLR
156
FDYDR
161
MASLE
166
CTVSL
171
DTART
176
RLPAH
181
GQMVL
186
GEPRP
191
EEPRG
196
DQPHS
201
FFPES
206
QLRAK
211
LKCPG
216
GSCTP
221
GLKKI
226
GSLKV
231
SCEEF
236
LLMGL
241
RYQHL
246
DPPSP
251
NIDYI
256
SIQLD
261
LTDTR
266
SKIVY
271
KSESA
276
WLPVY
281
IRAGI
286
PNQIP
291
KAAFM
296
AVFIL
301
EVDQF
306
ILTSL
311
TTSVL
316
DCEED
321
ETPKP
326
LLVFN
331
ITKAP
336
LQGYV
341
THLLD
346
HTRPI
351
SSFTW
356
KDLSD
361
MQIAY
366
QPPNS
371
SHSER
376
RHDEV
381
ELEVY
386
DFFFE
391
RSAPM
396
TVHIS
401
IRTAD
406
TNAPR
411
VSWNT
416
GLSLL
421
EGQSR
426
AITWE
431
QFQVV
436
DNDDI
441
GAVRL
446
VTVGG
451
LQHGW
456
LTLRG
461
GKGFL
466
FTVAD
471
LQAGV
476
VRYHH
481
DDSDS
486
TKDFV
491
VFRIF
496
DGHHS
501
IRHKF
506
PINVL
511
PKDDS
516
PPFLI
521
TNVVI
526
ELEEG
531
QTILI
536
QGSML
541
RASDV
546
DASDD
551
YIFFN
556
ITKPP
561
QAGEI
566
MKKPG
571
PGLIG
576
YPVHG
581
FLQRD
586
LFNGI
591
IYYRH
596
FGGEI
601
FEDSF
606
QFVLW
611
DSHEP
616
PNLSV
621
PQVAT
626
IHITP
631
VDDQL
636
PKEAP
641
GVSRH
646
LVVKE
651
TEVAY
656
ITKKQ
661
LHFID
666
SESYD
671
RELVY
676
TITTP
681
PFFSF
686
SHRHL
691
DAGKL
696
FMVDS
701
IPKVV
706
KNPTA
711
LELRS
716
FTQHA
721
VNYMK
726
VAYMP
731
PMQDI
736
GPHCR
741
DVQFT
746
FSVSN
751
QHGGT
756
LHGIC
761
FNITI
766
LPVDN
771
QVPEA
776
FTNPL
781
KVTEG
786
GQSII
791
STEHI
796
LISDA
801
DTKLD
806
NIDLS
811
LRELP
816
LHGRV
821
ELNGF
826
PLNSG
831
GTFSW
836
GDLHT
841
LKVRY
846
QHDGT
851
EVLQD
856
DLLLE
861
VTDGT
866
NSAEF
871
VLHVE
876
VFPVN
881
DEPPV
886
LKADL
891
MPVMN
896
CSEGG
901
EVVIT
906
SEYIF
911
ATDVD
916
SDNLK
921
LMFVI
926
AREPQ
931
HGVVR
936
RAGVT
941
VDQFS
946
QRDVI
951
SEAVT
956
YKHTG
961
GEIGL
966
MPCFD
971
TITLV
976
VSDGE
981
AGPFV
986
NGCCY
991
NGPNP
996
SVPLH
1001
ASFPV
1006
YDLNI
1011
TVYPV
1016
DNQPP
1021
SIAIG
1026
PVFVV
1031
DEGCS
1036
TALTV
1041
NHLSA
1046
TDPDT
1051
AADDL
1056
EFVLV
1061
SPPQF
1066
GYLEN
1071
ILPSV
1076
GFEKS
1081
NIGIS
1086
IDSFQ
1091
WKDMN
1096
AFHIN
1101
YVQSR
1106
HLRIE
1111
PTADQ
1116
FTVYV
1121
TDGKH
1126
HSLEI
1131
PFSII
1136
INPTN
1141
DEAPD
1146
FVVQN
1151
ITVCE
1156
GQMKE
1161
LDSSI
1166
ISAVD
1171
LDIPQ
1176
DALLF
1181
SITQK
1186
PRHGL
1191
LIDRG
1196
FSKDF
1201
SENKQ
1206
PANPH
1211
QKHAP
1216
VHSFS
1221
MELLK
1226
TGMRL
1231
TYMHD
1236
DSESL
1241
ADDFT
1246
IQLSD
1251
GKHKI
1256
LKTIS
1261
VEVIP
1266
VNDEK
1271
PMLSK
1276
KAEIA
1281
MNMGE
1286
TRIIS
1291
SAILS
1296
AIDED
1301
SPREK
1306
IYYVF
1311
ERLPQ
1316
NGQLQ
1321
LKIGR
1326
DWVPL
1331
SPGMK
1336
CTQEE
1341
VDLNL
1346
LRYTH
1351
TGAMD
1356
SQNQD
1361
SFTFY
1366
LWDGN
1371
NRSPA
1376
LDCQI
1381
TIKDM
1386
EKGDI
1391
VILTK
1396
PLVVS
1401
KGDRG
1406
FLTTT
1411
TLLAV
1416
DGTDK
1421
PEELL
1426
YVITS
1431
PPRYG
1436
QIEYV
1441
HYPGV
1446
PITNF
1451
SQMDV
1456
VGQTV
1461
CYVHK
1466
SKVTV
1471
SSDRF
1476
RFIIS
1481
NGLRT
1486
EHGVF
1491
EITLE
1496
TVDRA
1501
LPVVT
1506
RNKGL
1511
RLAQG
1516
AVGLL
1521
SPDLL
1526
QLTDP
1531
DTPAE
1536
NLTFL
1541
LVQLP
1546
QHGQL
1551
YLWGT
1556
GLLQH
1561
NFTQQ
1566
DVDSK
1571
NVAYR
1576
HSGGD
1581
SQTDC
1586
FTFMA
1591
TDGTN
1596
QGFIV
1601
NGRVW
1606
EEPVL
1611
FTIQV
1616
DQLDK
1621
TAPRI
1626
TLLHS
1631
PSQVG
1636
LLKNG
1641
CYGIY
1646
ITSRV
1651
LKASD
1656
PDTED
1661
DQIIF
1666
KILQG
1671
PKHGH
1676
LENTT
1681
TGEFI
1686
HEKFS
1691
QKDLN
1696
SKTIL
1701
YIINP
1706
SLEVN
1711
SDTVE
1716
FQIMD
1721
PTGNS
1726
ATPQI
1731
LELKW
1736
SHIEW
1741
SQTEY
1746
EVCEN
1751
VGLLP
1756
LEIIR
1761
RGYSM
1766
DSAFV
1771
GIKVN
1776
QVSAA
1781
VGKDF
1786
TVIPS
1791
KLIQF
1796
DPGMS
1801
TKMWN
1806
IAITY
1811
DGLEE
1816
DDEVF
1821
EVILN
1826
SPVNA
1831
VLGTK
1836
TKAAV
1841
KILDS
1846
KGGQC
1851
HPSYS
1856
SNQSK
1861
HSTWE
1866
KGIWH
1871
LLPPG
1876
SSSST
1881
TSGSF
1886
HLERR
1891
PLPSS
1896
MQLAV
1901
IRGDT
1906
LRGFD
1911
STDLS
1916
QRKLR
1921
TRGNG
1926
KTVRP
1931
SSVYR
1936
NGTDI
1941
IYNYH
1946
GIVSL
1951
KLEDD
1956
SFPTH
1961
KRKAK
1966
VSIIS
1971
QPQKT
1976
IKVAE
1981
LPQAD
1986
KVEST
1991
TDSHF
1996
PRQDQ
2001
LPSFP
2006
KNCTL
2011
ELKGL
2016
FHFEE
2021
GIQKL
2026
YQCNG
2031
IAWKA
2036
WSPQT
2041
KDVED
2046
KSCPA
2051
GWHQH
2056
SGYCH
2061
ILITE
2066
QKGTW
2071
NAAAQ
2076
ACREQ
2081
YLGNL
2086
VTVFS
2091
RQHMR
2096
WLWDI
2101
GGRKS
2106
FWIGL
2111
NDQVH
2116
AGHWE
2121
WIGGE
2126
PVAFT
2131
NGRRG
2136
PSQRS
2141
KLGKS
2146
CVLVQ
2151
RQGKW
2156
QTKDC
2161
RRAKP
2166
HNYVC
2171
SRKL
2176
Mutation Information
DNA mutation:
None
Peptide Range:
1188 ~ 1212
Mut AA position:
1200 (13 in Wild Type peptide)
Alignment
Wild Type:
"TQKPRHGLLIDRGFSKDFSENKQPA
||||||||||||.||||||||||||
Mutant:
TQKPRHGLLIDREFSKDFSENKQPA"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) FREM1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay