Immunogenicity 14505
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MED4
Transcript ID
NM_014166
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (270 aa)
MAASS
1
SGEKE
6
KERLG
11
GGLGV
16
AGGNS
21
TRERL
26
LSALE
31
DLEVL
36
SRELI
41
EMLAI
46
SRNQK
51
LLQAG
56
EENQV
61
LELLI
66
HRDGE
71
FQELM
76
KLALN
81
QGKIH
86
HEMQV
91
LEKEV
96
EKRDS
101
DIQQL
106
QKQLK
111
EAEQI
116
LATAV
121
YQAKE
126
KLKSI
131
EKARK
136
GAISS
141
EEIIK
146
YAHRI
151
SASNA
156
VCAPL
161
TWVPG
166
DPRRP
171
YPTDL
176
EMRSG
181
LLGQM
186
NNPST
191
NGVNG
196
HLPGD
201
ALAAG
206
RLPDV
211
LAPQY
216
PWQSN
221
DMSMN
226
MLPPN
231
HSSDF
236
LLEPP
241
GHNKE
246
NEDDV
251
EIMST
256
DSSSS
261
SSESD
266
Mutation Information
DNA mutation:
None
Peptide Range:
161 ~ 185
Mut AA position:
173 (13 in Wild Type peptide)
Alignment
Wild Type:
"VCAPLTWVPGDPRRPYPTDLEMRSG
||||||||||||.||||||||||||
Mutant:
VCAPLTWVPGDPWRPYPTDLEMRSG"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) MED4
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay