Immunogenicity 14555
Sample ID
3903
Response
Negative
Tumor Type
Melanoma
Gene Symbol
RUVBL1
Transcript ID
NM_003707
HLA INFO
B*38:01
TCR INFO
No TCR info found!
Full length protein sequence (456 aa)
MKIEE
1
VKSTT
6
KTQRI
11
ASHSH
16
VKGLG
21
LDESG
26
LAKQA
31
ASGLV
36
GQENA
41
REACG
46
VIVEL
51
IKSKK
56
MAGRA
61
VLLAG
66
PPGTG
71
KTALA
76
LAIAQ
81
ELGSK
86
VPFCP
91
MVGSE
96
VYSTE
101
IKKTE
106
VLMEN
111
FRRAI
116
GLRIK
121
ETKEV
126
YEGEV
131
TELTP
136
CETEN
141
PMGGY
146
GKTIS
151
HVIIG
156
LKTAK
161
GTKQL
166
KLDPS
171
IFESL
176
QKERV
181
EAGDV
186
IYIEA
191
NSGAV
196
KRQGR
201
CDTYA
206
TEFDL
211
EAEEY
216
VPLPK
221
GDVHK
226
KKEII
231
QDVTL
236
HDLDV
241
ANARP
246
QGGQD
251
ILSMM
256
GQLMK
261
PKKTE
266
ITDKL
271
RGEIN
276
KVVNK
281
YIDQG
286
IAELV
291
PGVLF
296
VDEVH
301
MLDIE
306
CFTYL
311
HRALE
316
SSIAP
321
IVIFA
326
SNRGN
331
CVIRG
336
TEDIT
341
SPHGI
346
PLDLL
351
DRVMI
356
IRTML
361
YTPQE
366
MKQII
371
KIRAQ
376
TEGIN
381
ISEEA
386
LNHLG
391
EIGTK
396
TTLRY
401
SVQLL
406
TPANL
411
LAKIN
416
GKDSI
421
EKEHV
426
EEISE
431
LFYDA
436
KSSAK
441
ILADQ
446
QDKYM
451
K
456
Mutation Information
DNA mutation:
None
Peptide Range:
409 ~ 433
Mut AA position:
421 (13 in Wild Type peptide)
Alignment
Wild Type:
"LLTPANLLAKINGKDSIEKEHVEEI
||||||||||||.||||||||||||
Mutant:
LLTPANLLAKINEKDSIEKEHVEEI"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) RUVBL1
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay