Immunogenicity 14613

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
MTHFD2L
Transcript ID
NM_001144978
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (347 aa)
MTVPV
1
RGFSL
6
LRGRL
11
GRAPA
16
LGRST
21
APSVR
26
APGEP
31
GSAFR
36
GFRSS
41
GVRHE
46
AIIIS
51
GTEMA
56
KHIQK
61
EIQRG
66
VESWV
71
SLGNR
76
RPHLS
81
IILVG
86
DNPAS
91
HTYVR
96
NKIRA
101
ASAVG
106
ICSEL
111
ILKPK
116
DVSQE
121
ELLDV
126
TDQLN
131
MDPRV
136
SGILV
141
QLPLP
146
DHVDE
151
RTICN
156
GIAPE
161
KDVDG
166
FHIIN
171
IGRLC
176
LDQHS
181
LIPAT
186
ASAVW
191
EIIKR
196
TGIQT
201
FGKNV
206
VVAGR
211
SKNVG
216
MPIAM
221
LLHTD
226
GEHER
231
PGGDA
236
TVTIA
241
HRYTP
246
KEQLK
251
IHTQL
256
ADIII
261
VAAGI
266
PKLIT
271
SDMVK
276
EGAAV
281
IDVGI
286
NYVHD
291
PVTGK
296
TKLVG
301
DVDFE
306
AVKKK
311
AGFIT
316
PVPGG
321
VGPMT
326
VAMLL
331
KNTLL
336
AAKKI
341
IY
346
Mutation Information
DNA mutation:
None
Peptide Range:
126 ~ 150
Mut AA position:
138 (13 in Wild Type peptide)
Alignment
Wild Type:
"ELLDVTDQLNMDPRVSGILVQLPLP
||||||||||||.||||||||||||
Mutant:
ELLDVTDQLNMDLRVSGILVQLPLP"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay