Immunogenicity 14628
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
ITCH
Transcript ID
NM_001257137
HLA INFO
A*03:01
TCR INFO
No TCR info found!
Full length protein sequence (903 aa)
MSDSG
1
SQLGS
6
MGSLT
11
MKSQL
16
QITVI
21
SAKLK
26
ENKKN
31
WFGPS
36
PYVEV
41
TVDGQ
46
SKKTE
51
KCNNT
56
NSPKW
61
KQPLT
66
VIVTP
71
VSKLH
76
FRVWS
81
HQTLK
86
SDVLL
91
GTAAL
96
DIYET
101
LKSNN
106
MKLEE
111
VVVTL
116
QLGGD
121
KEPTE
126
TIGDL
131
SICLD
136
GLQLE
141
SEVVT
146
NGETT
151
CSENG
156
VSLCL
161
PRLEC
166
NSAIS
171
AHCNL
176
CLPGL
181
SDSPI
186
SASRV
191
AGFTG
196
ASQND
201
DGSRS
206
KDETR
211
VSTNG
216
SDDPE
221
DAGAG
226
ENRRV
231
SGNNS
236
PSLSN
241
GGFKP
246
SRPPR
251
PSRPP
256
PPTPR
261
RPASV
266
NGSPS
271
ATSES
276
DGSST
281
GSLPP
286
TNTNT
291
NTSEG
296
ATSGL
301
IIPLT
306
ISGGS
311
GPRPL
316
NPVTQ
321
APLPP
326
GWEQR
331
VDQHG
336
RVYYV
341
DHVEK
346
RTTWD
351
RPEPL
356
PPGWE
361
RRVDN
366
MGRIY
371
YVDHF
376
TRTTT
381
WQRPT
386
LESVR
391
NYEQW
396
QLQRS
401
QLQGA
406
MQQFN
411
QRFIY
416
GNQDL
421
FATSQ
426
SKEFD
431
PLGPL
436
PPGWE
441
KRTDS
446
NGRVY
451
FVNHN
456
TRITQ
461
WEDPR
466
SQGQL
471
NEKPL
476
PEGWE
481
MRFTV
486
DGIPY
491
FVDHN
496
RRTTT
501
YIDPR
506
TGKSA
511
LDNGP
516
QIAYV
521
RDFKA
526
KVQYF
531
RFWCQ
536
QLAMP
541
QHIKI
546
TVTRK
551
TLFED
556
SFQQI
561
MSFSP
566
QDLRR
571
RLWVI
576
FPGEE
581
GLDYG
586
GVARE
591
WFFLL
596
SHEVL
601
NPMYC
606
LFEYA
611
GKDNY
616
CLQIN
621
PASYI
626
NPDHL
631
KYFRF
636
IGRFI
641
AMALF
646
HGKFI
651
DTGFS
656
LPFYK
661
RILNK
666
PVGLK
671
DLESI
676
DPEFY
681
NSLIW
686
VKENN
691
IEECD
696
LEMYF
701
SVDKE
706
ILGEI
711
KSHDL
716
KPNGG
721
NILVT
726
EENKE
731
EYIRM
736
VAEWR
741
LSRGV
746
EEQTQ
751
AFFEG
756
FNEIL
761
PQQYL
766
QYFDA
771
KELEV
776
LLCGM
781
QEIDL
786
NDWQR
791
HAIYR
796
HYART
801
SKQIM
806
WFWQF
811
VKEID
816
NEKRM
821
RLLQF
826
VTGTC
831
RLPVG
836
GFADL
841
MGSNG
846
PQKFC
851
IEKVG
856
KENWL
861
PRSHT
866
CFNRL
871
DLPPY
876
KSYEQ
881
LKEKL
886
LFAIE
891
ETEGF
896
GQE
901
Mutation Information
DNA mutation:
None
Peptide Range:
819 ~ 843
Mut AA position:
831 (13 in Wild Type peptide)
Alignment
Wild Type:
"IDNEKRMRLLQFVTGTCRLPVGGFA
||||||||||||.||||||||||||
Mutant:
IDNEKRMRLLQFITGTCRLPVGGFA"
Nat Med, 2016
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patientsGene Name (from Reference) ITCH
Checkpoint
Blockade
None
ACT
None
Vaccination
None
Curative
Effect
None
minimal_peptide
None
Antigen
Type
TMG RNA
T-cell
Source
PBMCs
APC
Type
autologous DCs
Assay
IFNg ELISPOT assay