Immunogenicity 14663

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SETD2
Transcript ID
NM_014159
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (2564 aa)
MKQLQ
1
PQPPP
6
KMGDF
11
YDPEH
16
PTPEE
21
EENEA
26
KIENV
31
QKTGF
36
IKGPM
41
FKGVA
46
SSRFL
51
PKGTK
56
TKVNL
61
EEQGR
66
QKVSF
71
SFSLT
76
KKTLQ
81
NRFLT
86
ALGNE
91
KQSDT
96
PNPPA
101
VPLQV
106
DSTPK
111
MKMEI
116
GDTLS
121
TAEES
126
SPPKS
131
RVELG
136
KIHFK
141
KHLLH
146
VTSRP
151
LLATT
156
TAVAS
161
PPTHA
166
APLPA
171
VIAES
176
TTVDS
181
PPSSP
186
PPPPP
191
PAQAT
196
TLSSP
201
APVTE
206
PVALP
211
HTPIT
216
VLMAA
221
PVPLP
226
VDVAV
231
RSLKE
236
PPIII
241
VPESL
246
EADTK
251
QDTIS
256
NSLEE
261
HVTQI
266
LNEQA
271
DISSK
276
KEDSH
281
IGKDE
286
EIPDS
291
SKISL
296
SCKKT
301
GSKKK
306
SSQSE
311
GIFLG
316
SESDE
321
DSVRT
326
SSSQR
331
SHDLK
336
FSASI
341
EKERD
346
FKKSS
351
APLKS
356
EDLGK
361
PSRSK
366
TDRDD
371
KYFSY
376
SKLER
381
DTRYV
386
SSRCR
391
SERER
396
RRSRS
401
HSRSE
406
RGSRT
411
NLSYS
416
RSERS
421
HYYDS
426
DRRYH
431
RSSPY
436
RERTR
441
YSRPY
446
TDNRA
451
RESSD
456
SEEEY
461
KKTYS
466
RRTSS
471
HSSSY
476
RDLRT
481
SSYSK
486
SDRDC
491
KTETS
496
YLEME
501
RRGKY
506
SSKLE
511
RESKR
516
TSENE
521
AIKRC
526
CSPPN
531
ELGFR
536
RGSSY
541
SKHDS
546
SASRY
551
KSTLS
556
KPIPK
561
SDKFK
566
NSFCC
571
TELNE
576
EIKQS
581
HSFSL
586
QTPCS
591
KGSEL
596
RMINK
601
NPERE
606
KAGSP
611
APSNR
616
LNDSP
621
TLKKL
626
DELPI
631
FKSEF
636
ITHDS
641
HDSIK
646
ELDSL
651
SKVKN
656
DQLRS
661
FCPIE
666
LNING
671
SPGAE
676
SDLAT
681
FCTSK
686
TDAVL
691
MTSDD
696
SVTGS
701
ELSPL
706
VKACM
711
LSSNG
716
FQNIS
721
RCKEK
726
DLDDT
731
CMLHK
736
KSESP
741
FRETE
746
PLVSP
751
HQDKL
756
MSMPV
761
MTVDY
766
SKTVV
771
KEPVD
776
TRVSC
781
CKTKD
786
SDIYC
791
TLNDS
796
NPSLC
801
NSEAE
806
NIEPS
811
VMKIS
816
SNSFM
821
NVHLE
826
SKPVI
831
CDSRN
836
LTDHS
841
KFACE
846
EYKQS
851
IGSTS
856
SASVN
861
HFDDL
866
YQPIG
871
SSGIA
876
SSLQS
881
LPPGI
886
KVDSL
891
TLLKC
896
GENTS
901
PVLDA
906
VLKSK
911
KSSEF
916
LKHAG
921
KETIV
926
EVGSD
931
LPDSG
936
KGFAS
941
RENRR
946
NNGLS
951
GKCLQ
956
EAQEE
961
GNSIL
966
PERRG
971
RPEIS
976
LDERG
981
EGGHV
986
HTSDD
991
SEVVF
996
SSCDL
1001
NLTME
1006
DSDGV
1011
TYALK
1016
CDSSG
1021
HAPEI
1026
VSTVH
1031
EDYSG
1036
SSESS
1041
NDESD
1046
SEDTD
1051
SDDSS
1056
IPRNR
1061
LQSVV
1066
VVPKN
1071
STLPM
1076
EETSP
1081
CSSRS
1086
SQSYR
1091
HYSDH
1096
WEDER
1101
LESRR
1106
HLYEE
1111
KFESI
1116
ASKAC
1121
PQTDK
1126
FFLHK
1131
GTEKN
1136
PEISF
1141
TQSSR
1146
KQIDN
1151
RLPEL
1156
SHPQS
1161
DGVDS
1166
TSHTD
1171
VKSDP
1176
LGHPN
1181
SEETV
1186
KAKIP
1191
SRQQE
1196
ELPIY
1201
SSDFE
1206
DVPNK
1211
SWQQT
1216
TFQNR
1221
PDSRL
1226
GKTEL
1231
SFSSS
1236
CEIPH
1241
VDGLH
1246
SSEEL
1251
RNLGW
1256
DFSQE
1261
KPSTT
1266
YQQPD
1271
SSYGA
1276
CGGHK
1281
YQQNA
1286
EQYGG
1291
TRDYW
1296
QGNGY
1301
WDPRS
1306
GRPPG
1311
TGVVY
1316
DRTQG
1321
QVPDS
1326
LTDDR
1331
EEEEN
1336
WDQQD
1341
GSHFS
1346
DQSDK
1351
FLLSL
1356
QKDKG
1361
SVQAP
1366
EISSN
1371
SIKDT
1376
LAVNE
1381
KKDFS
1386
KNLEK
1391
NDIKD
1396
RGPLK
1401
KRRQE
1406
IESDS
1411
ESDGE
1416
LQDRK
1421
KVRVE
1426
VEQGE
1431
TSVPP
1436
GSALV
1441
GPSCV
1446
MDDFR
1451
DPQRW
1456
KECAK
1461
QGKMP
1466
CYFDL
1471
IEENV
1476
YLTER
1481
KKNKS
1486
HRDIK
1491
RMQCE
1496
CTPLS
1501
KDERA
1506
QGEIA
1511
CGEDC
1516
LNRLL
1521
MIECS
1526
SRCPN
1531
GDYCS
1536
NRRFQ
1541
RKQHA
1546
DVEVI
1551
LTEKK
1556
GWGLR
1561
AAKDL
1566
PSNTF
1571
VLEYC
1576
GEVLD
1581
HKEFK
1586
ARVKE
1591
YARNK
1596
NIHYY
1601
FMALK
1606
NDEII
1611
DATQK
1616
GNCSR
1621
FMNHS
1626
CEPNC
1631
ETQKW
1636
TVNGQ
1641
LRVGF
1646
FTTKL
1651
VPSGS
1656
ELTFD
1661
YQFQR
1666
YGKEA
1671
QKCFC
1676
GSANC
1681
RGYLG
1686
GENRV
1691
SIRAA
1696
GGKMK
1701
KERSR
1706
KKDSV
1711
DGELE
1716
ALMEN
1721
GEGLS
1726
DKNQV
1731
LSLSR
1736
LMVRI
1741
ETLEQ
1746
KLTCL
1751
ELIQN
1756
THSQS
1761
CLKSF
1766
LERHG
1771
LSLLW
1776
IWMAE
1781
LGDGR
1786
ESNQK
1791
LQEEI
1796
IKTLE
1801
HLPIP
1806
TKNML
1811
EESKV
1816
LPIIQ
1821
RWSQT
1826
KTAVP
1831
PLSEG
1836
DGYSS
1841
ENTSR
1846
AHTPL
1851
NTPDP
1856
STKLS
1861
TEADT
1866
DTPKK
1871
LMFRR
1876
LKIIS
1881
ENSMD
1886
SAISD
1891
ATSEL
1896
EGKDG
1901
KEDLD
1906
QLENV
1911
PVEEE
1916
EELQS
1921
QQLLP
1926
QQLPE
1931
CKVDS
1936
ETNIE
1941
ASKLP
1946
TSEPE
1951
ADAEI
1956
EPKES
1961
NGTKL
1966
EEPIN
1971
EETPS
1976
QDEEE
1981
GVSDV
1986
ESERS
1991
QEQPD
1996
KTVDI
2001
SDLAT
2006
KLLDS
2011
WKDLK
2016
EVYRI
2021
PKKSQ
2026
TEKEN
2031
TTTER
2036
GRDAV
2041
GFRDQ
2046
TPAPK
2051
TPNRS
2056
RERDP
2061
DKQTQ
2066
NKEKR
2071
KRRSS
2076
LSPPS
2081
SAYER
2086
GTKRP
2091
DDRYD
2096
TPTSK
2101
KKVRI
2106
KDRNK
2111
LSTEE
2116
RRKLF
2121
EQEVA
2126
QREAQ
2131
KQQQQ
2136
MQNLG
2141
MTSPL
2146
PYDSL
2151
GYNAP
2156
HHPFA
2161
GYPPG
2166
YPMQA
2171
YVDPS
2176
NPNAG
2181
KVLLP
2186
TPSMD
2191
PVCSP
2196
APYDH
2201
AQPLV
2206
GHSTE
2211
PLSAP
2216
PPVPV
2221
VPHVA
2226
APVEV
2231
SSSQY
2236
VAQSD
2241
GVVHQ
2246
DSSVA
2251
VLPVP
2256
APGPV
2261
QGQNY
2266
SVWDS
2271
NQQSV
2276
SVQQQ
2281
YSPAQ
2286
SQATI
2291
YYQGQ
2296
TCPTV
2301
YGVTS
2306
PYSQT
2311
TPPIV
2316
QSYAQ
2321
PSLQY
2326
IQGQQ
2331
IFTAH
2336
PQGVV
2341
VQPAA
2346
AVTTI
2351
VAPGQ
2356
PQPLQ
2361
PSEMV
2366
VTNNL
2371
LDLPP
2376
PSPPK
2381
PKTIV
2386
LPPNW
2391
KTARD
2396
PEGKI
2401
YYYHV
2406
ITRQT
2411
QWDPP
2416
TWESP
2421
GDDAS
2426
LEHEA
2431
EMDLG
2436
TPTYD
2441
ENPMK
2446
ASKKP
2451
KTAEA
2456
DTSSE
2461
LAKKS
2466
KEVFR
2471
KEMSQ
2476
FIVQC
2481
LNPYR
2486
KPDCK
2491
VGRIT
2496
TTEDF
2501
KHLAR
2506
KLTHG
2511
VMNKE
2516
LKYCK
2521
NPEDL
2526
ECNEN
2531
VKHKT
2536
KEYIK
2541
KYMQK
2546
FGAVY
2551
KPKED
2556
TELE
2561
Mutation Information
DNA mutation:
None
Peptide Range:
1489 ~ 1513
Mut AA position:
1501 (13 in Wild Type peptide)
Alignment
Wild Type:
"KSHRDIKRMQCECTPLSKDERAQGE
||||||||||||.||||||||||||
Mutant:
KSHRDIKRMQCEYTPLSKDERAQGE"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay