Immunogenicity 14687

summary
Sample ID
3784
Response
Negative
Tumor Type
Melanoma
Gene Symbol
SZT2
Transcript ID
NM_015284
HLA INFO
B*07:01
TCR INFO

No TCR info found!

T cell Tumor cell B*07:01
sequence
Full length protein sequence (3375 aa)
MASER
1
PEPEV
6
EEAGQ
11
VFLLM
16
KKDYR
21
ISRNV
26
RLAWF
31
LSHLH
36
QTVQA
41
TPQEM
46
LLQSE
51
QELEV
56
LSVLP
61
PGWQP
66
DEPVV
71
PRPFL
76
LVPST
81
RVTFL
86
AWQYR
91
FVIEL
96
DLSPS
101
TGIVD
106
DSTGE
111
ILFDE
116
VFHAL
121
SRCLG
126
GLLRP
131
FRVPG
136
SCIDF
141
QPEIY
146
VTIQA
151
YSSII
156
GLQSH
161
QVLVQ
166
GCLLD
171
PSQRE
176
VFLQQ
181
IYEQL
186
CLFED
191
KVATM
196
LQQQY
201
DPQSQ
206
AEDQS
211
PDSGD
216
LLGRK
221
VGVSM
226
VTADL
231
GLVSM
236
IRQGI
241
LALQL
246
LPSNS
251
SAGII
256
VITDG
261
VTSVP
266
DVAVC
271
ETLLN
276
QLRSG
281
TVACS
286
FVQVG
291
GVYSY
296
DCSFG
301
HVPNV
306
ELMKF
311
IAMAT
316
FGSYL
321
STCPE
326
PEPGN
331
LGLTV
336
YHRAF
341
LLYSF
346
LRSGE
351
ALNPE
356
YYCGS
361
QHRLF
366
NEHLV
371
SASSN
376
PALAL
381
RRKKH
386
TEKEV
391
PADLV
396
STVSV
401
RLREG
406
YSVRE
411
VTLAK
416
GGSQL
421
EVKLV
426
LLWKH
431
NMRIE
436
YVAMA
441
PWPLE
446
PEGPR
451
VTRVE
456
VTMEG
461
GYDIL
466
HDVSC
471
ALRQP
476
IRSLY
481
RTHVI
486
RRFWN
491
TLQSI
496
NQTDQ
501
MLAHL
506
QSFSS
511
VPEHF
516
TLPDS
521
TKSGV
526
PLFYI
531
PPGST
536
TPVLS
541
LQPSG
546
SDSSH
551
AQFAA
556
YWKPV
561
LSMDA
566
NSWQR
571
WLHMH
576
RLVLI
581
LEHDT
586
PIPKH
591
LHTPG
596
SNGRY
601
STIQC
606
RISHS
611
SLTSL
616
LRDWS
621
SFVLV
626
EGYSY
631
VKLLS
636
SAPDQ
641
PPNSF
646
YMVRI
651
ISKAP
656
CMVLR
661
LGFPI
666
GTPAP
671
ARHKI
676
VSGLR
681
EEILR
686
LRFPH
691
RVQSK
696
EPTPK
701
VKRKG
706
LGGAG
711
GGSSP
716
SKSPP
721
VLGPQ
726
QALSD
731
RPCLV
736
VLHKP
741
LDKLL
746
IRYEK
751
LPLDY
756
RAPFL
761
LTLEP
766
PGPLP
771
LVSGR
776
SASSS
781
LASLS
786
RYLYH
791
QRWLW
796
SVPSG
801
LAPAL
806
PLSAI
811
AQLLS
816
ILTEV
821
RLSEG
826
FHFAC
831
SGEGI
836
INMVL
841
ELPIQ
846
NEPPG
851
QAAAE
856
EKHTC
861
VVQYI
866
LFPPH
871
STSTK
876
DSFST
881
DDDND
886
VEVEA
891
LEGDS
896
ELNLV
901
TEVWV
906
EPQYG
911
RVGPG
916
PGIWK
921
HLQDL
926
TYSEI
931
PQALH
936
PRDAA
941
CIGSM
946
LSFEY
951
LIQLC
956
QSKEW
961
GPLPP
966
EPRVS
971
DGLDQ
976
GGDTC
981
VHEIP
986
FHFDL
991
MGLLP
996
QCQQL
1001
QMFFL
1006
LLARG
1011
AEGPL
1016
LGVHG
1021
IPKEQ
1026
AVGST
1031
QATGD
1036
SAFTS
1041
LSVGL
1046
PETLK
1051
PLISA
1056
QPPQW
1061
RCYAR
1066
LVNPQ
1071
HVFLT
1076
FLPAT
1081
FSDVQ
1086
RLAAC
1091
GLEGP
1096
PQEET
1101
KPKFG
1106
DWSGA
1111
PSLKD
1116
LGGTG
1121
IKATK
1126
SHVPV
1131
LSVTL
1136
ASDNA
1141
QNQGE
1146
LSPPF
1151
RRDLQ
1156
AYAGR
1161
QASQT
1166
ESADG
1171
PRTRC
1176
PVYIY
1181
SCSLE
1186
ALREQ
1191
MVGMQ
1196
PPQAP
1201
RDLIF
1206
RTQFL
1211
DHPSP
1216
SSAWM
1221
EPRYK
1226
EAANH
1231
CALLQ
1236
EHAQR
1241
CYVRG
1246
LFRSL
1251
QQAQS
1256
VTSQD
1261
LLTAV
1266
DACEE
1271
LLQEI
1276
DITPF
1281
LLALC
1286
GHTWG
1291
LPHAP
1296
PSPGP
1301
LSPGP
1306
FSSSM
1311
EEGAE
1316
PRERA
1321
ILASE
1326
SSIET
1331
EDLSE
1336
PEFQS
1341
TRVPG
1346
IPDPG
1351
PEISL
1356
TDVCQ
1361
LRGEA
1366
HGALH
1371
SVIQE
1376
KFLEI
1381
SRLHF
1386
RTVPS
1391
NPHYF
1396
FYCPP
1401
SSRRE
1406
DEGPR
1411
DTVDR
1416
KISDL
1421
EFSEA
1426
ELMGE
1431
EGDTS
1436
ACCVV
1441
TESDP
1446
ELEVE
1451
YRESR
1456
ESDLG
1461
PAGLD
1466
SASLS
1471
DVDTV
1476
NPDED
1481
SFSIL
1486
GGDSP
1491
TGPES
1496
FLHDL
1501
PPLFL
1506
HLTCS
1511
VRLRG
1516
QHSSV
1521
PVCSL
1526
PTCLG
1531
QVLSS
1536
LEGPP
1541
VGGRV
1546
PLRDL
1551
SVTLD
1556
VFMLT
1561
LPLEV
1566
ELPTA
1571
SDPQH
1576
HRSTS
1581
ESSAS
1586
FPRSP
1591
GQPSS
1596
LRSDD
1601
GLGPP
1606
LPPPE
1611
EERHP
1616
GLSNL
1621
ATPHR
1626
LAIET
1631
TMNEI
1636
RWLLE
1641
DEMVG
1646
ALRRG
1651
GIPQS
1656
PALHR
1661
AAAHI
1666
HSSPG
1671
RSTCL
1676
RQTLP
1681
LSFVF
1686
GPERS
1691
LTQFK
1696
EEFRR
1701
LHLPG
1706
HVLLE
1711
DPDSG
1716
FFFVA
1721
AGQQP
1726
GGSHG
1731
EPSSA
1736
AWAWH
1741
SHEDR
1746
AEGIE
1751
GETLT
1756
ASPQA
1761
PGSPE
1766
DSEGV
1771
PLISL
1776
PRVPQ
1781
GGSQP
1786
GPSRG
1791
LSLMS
1796
SQGSV
1801
DSDHL
1806
GYDGG
1811
SSGSD
1816
SEGPN
1821
DTLGE
1826
KAPFT
1831
LRTPP
1836
GPAPP
1841
QPSLS
1846
GLPGP
1851
CLPDF
1856
WLIVR
1861
VLQDR
1866
VEVYA
1871
HARSL
1876
IREDG
1881
GPGTE
1886
CRHLQ
1891
QLLVR
1896
RVGEI
1901
CREVN
1906
QRLLL
1911
QDLHD
1916
SHVCN
1921
SLLVA
1926
ESEED
1931
LWRSE
1936
TPFHS
1941
RQRAP
1946
LPSDD
1951
YAADE
1956
SCAPR
1961
GYLAA
1966
TMQFV
1971
PGHFS
1976
CDVVW
1981
GTVIR
1986
VHSRL
1991
KMGPS
1996
MGVSR
2001
AIQAL
2006
RSVLN
2011
AFSVV
2016
NRKNM
2021
FVYQE
2026
RATKA
2031
VYYLR
2036
LLETS
2041
CSDRP
2046
WKGDA
2051
LPPSL
2056
ALSRS
2061
QEPIY
2066
SEEAS
2071
GPRSP
2076
LDMVS
2081
SRSSD
2086
AARPV
2091
GQVDR
2096
HIQLL
2101
VHGVG
2106
QAGPE
2111
ITDEL
2116
VRVLC
2121
RRLDE
2126
ATLDV
2131
ITVML
2136
VRNCK
2141
LTPAD
2146
VEFIQ
2151
PPGSL
2156
PSEVL
2161
HLALP
2166
TSCRP
2171
WLPAL
2176
AWYLR
2181
QNLLI
2186
FLHSP
2191
KYTDS
2196
NSRNH
2201
FQHPL
2206
PPQGG
2211
LPDLD
2216
IYLYN
2221
KPGGQ
2226
GTGGK
2231
GVACI
2236
TLAFV
2241
DEGGA
2246
PLSLA
2251
LWPPS
2256
SPGPP
2261
DPLRE
2266
EEFEQ
2271
LTQVI
2276
RCPVV
2281
VDSSS
2286
AQNGA
2291
PRLRL
2296
DVWEK
2301
GNISI
2306
VQLEE
2311
KLRGA
2316
ARQAL
2321
ADAII
2326
ELQLL
2331
PASLC
2336
TEDTP
2341
TGSLR
2346
NGSLE
2351
TKSSA
2356
GRAST
2361
FPPAP
2366
VPGEP
2371
VTPPS
2376
KAGRR
2381
SFWDM
2386
LSKTE
2391
CGDLG
2396
SPKTT
2401
DDIVL
2406
DRPED
2411
TRGRR
2416
RHKTE
2421
SVRTP
2426
GGAER
2431
APGSD
2436
SGAQR
2441
QKRRT
2446
TQLEE
2451
GEVGT
2456
LHPVF
2461
ARVAQ
2466
RWMEF
2471
MVQIG
2476
CASVS
2481
RSSAH
2486
MVSRF
2491
LLPSI
2496
LSEFT
2501
ALVTS
2506
MAGDT
2511
SVRIF
2516
EQHLG
2521
SEPEI
2526
FGPCS
2531
PGQLG
2536
PSPRP
2541
AAERH
2546
LLLLG
2551
RNFLQ
2556
WRRPT
2561
QQAAK
2566
AMQRF
2571
EPGGD
2576
GSSGR
2581
NAPRQ
2586
RLLLL
2591
EVVDK
2596
KLQLL
2601
TYNWA
2606
PDLGA
2611
ALGRA
2616
LVRLV
2621
QWQNA
2626
RAHLI
2631
FCLLS
2636
QKLGL
2641
FHHYG
2646
QLDFP
2651
VRDEK
2656
EPNPF
2661
LLPTM
2666
EVETL
2671
IRSAS
2676
PPLSR
2681
EQGRL
2686
SGSSR
2691
GGGPL
2696
PLDTF
2701
PFDEA
2706
LRDIT
2711
AARPS
2716
SVLGP
2721
VPRPP
2726
DPVTY
2731
HGQQF
2736
LEIKM
2741
AERRE
2746
LERQM
2751
KMENL
2756
FVTWQ
2761
QRSTP
2766
ATMPI
2771
SAGEL
2776
ETLKQ
2781
SSRLV
2786
HYCAT
2791
AMLFD
2796
PAAWL
2801
HGPPE
2806
TSGPP
2811
DGQRR
2816
HRPES
2821
GSGSR
2826
EAPTS
2831
CESLD
2836
VSPPG
2841
AREEP
2846
WLKEL
2851
SLAFL
2856
QQYVQ
2861
YLQSI
2866
GFVLV
2871
PLRPP
2876
SPARS
2881
TSRPR
2886
AMAIL
2891
GTEGR
2896
GSFSC
2901
PKTKT
2906
DGSPK
2911
STSSP
2916
VTTYH
2921
LQRAL
2926
PGGII
2931
LMELA
2936
FQGCY
2941
FCVKQ
2946
FALEC
2951
SRIPM
2956
GQAVN
2961
SQLSM
2966
LFTEE
2971
CDKVR
2976
DLMHV
2981
HSFSY
2986
DFHLR
2991
LVHQH
2996
VLGAH
3001
LVLRH
3006
GYHLT
3011
TFLRH
3016
FLAHH
3021
PDGPH
3026
FGRNH
3031
IYQGT
3036
LELPT
3041
PLIAA
3046
HQLYN
3051
YVADH
3056
ASSYH
3061
MKPLR
3066
MARPG
3071
GPEHN
3076
EYALV
3081
SAWHS
3086
SGSYL
3091
DSEGL
3096
RHQDD
3101
FDVSL
3106
LVCHC
3111
AAPFE
3116
EQGEA
3121
ERHVL
3126
RLQFF
3131
VVLTS
3136
QRELF
3141
PRLTA
3146
DMRRF
3151
RKPPR
3156
LPPEP
3161
EAPGS
3166
SAGSP
3171
GEASG
3176
LILAP
3181
GPAPL
3186
FPPLA
3191
AEVGM
3196
ARARL
3201
AQLVR
3206
LAGGH
3211
CRRDT
3216
LWKRL
3221
FLLEP
3226
PGPDR
3231
LRLGG
3236
RLALA
3241
ELEEL
3246
LEAVH
3251
AKSIG
3256
DIDPQ
3261
LDCFL
3266
SMTVS
3271
WYQSL
3276
IKVLL
3281
SRFPQ
3286
SCRHF
3291
QSPDL
3296
GTQYL
3301
VVLNQ
3306
KFTDC
3311
FVLVF
3316
LDSHL
3321
GKTSL
3326
TVVFR
3331
EPFPV
3336
QPQDS
3341
ESPPA
3346
QLVST
3351
YHHLE
3356
SVINT
3361
ACFTL
3366
WTRLL
3371
Mutation Information
DNA mutation:
None
Peptide Range:
1564 ~ 1588
Mut AA position:
1576 (13 in Wild Type peptide)
Alignment
Wild Type:
"LTLPLEVELPTASDPQHHRSTSESS
||||||||||||.||||||||||||
Mutant:
LTLPLEVELPTALDPQHHRSTSESS"
reference
clinic trial
Checkpoint Blockade

None

ACT

None

Vaccination

None

Curative Effect

None

experiment
minimal_peptide

None

Antigen Type

TMG RNA

T-cell Source

PBMCs

APC Type

autologous DCs

Assay

IFNg ELISPOT assay